Harnessing radical mediated reactions of thioacids for organic synthesis

Alby Benny, Mark D. Nolan and Eoin M. Scanlan

Chem. Commun., 2025, 61, 5883
DOI: 10.1039/D5CC00123D

A thiol–ene mediated approach for peptide bioconjugation using ‘green’ solvents under continuous flow

Inés Rabadán González, Joshua T. McLean, Nikita Ostrovitsa, Sheila Fitzgerald, Andrea Mezzetta, Lorenzo Guazzelli, Donal F. O'Shea and Eoin M. Scanlan

Org. Biomol. Chem., 2024, 22, 2203
DOI: 10.1039/D4OB00122B

Copper(i)-catalyzed click chemistry in deep eutectic solvent for the syntheses of β-d-glucopyranosyltriazoles

Subrat Sethi, Narayan Ch. Jana, Surajit Panda, Suraj Kumar Maharana and Bidraha Bagh

RSC Adv., 2023, 13, 10424
DOI: 10.1039/D3RA01844J

Ionic liquids and deep eutectic solvents for the stabilization of biopharmaceuticals: A review

Nathalia Vieira Porphirio Veríssimo, Cassamo Usemane Mussagy, Heitor Buzetti Simões Bento, Jorge Fernando Brandão Pereira and Valéria de Carvalho Santos-Ebinuma

Biotechnology Advances, 2024, 71, 108316
DOI: 10.1016/j.biotechadv.2024.108316

The effects of experimental conditions on extraction of polyphenols from African Nutmeg peels using NADESs-UAE: a multifactorial modelling technique

Udodinma Jude Okeke, Matteo Micucci, Dasha Mihaylova and Achile Cappiello

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-88233-8

Photo‐and Electrochemical Modification of Amino Acids, Peptides and Proteins through Cysteine: Recent Advances and Future Perspectives

Fang Xiang, Fan Hu, Yue Weng and Meng Gao

Eur J Org Chem, 2024, 27
DOI: 10.1002/ejoc.202400772

Molecular insights into azeotrope separation in the methyl tert-butyl ether production process using ChCl-based deep eutectic solvents

Yasen Dai, Xiaojun Chu, Yuyang Jiao, Yanan Li, Falong Shan, Shuai Zhao, Guoxuan Li, Zhigang Lei, Peizhe Cui, Zhaoyou Zhu and Yinglong Wang

Chemical Engineering Science, 2022, 264, 118179
DOI: 10.1016/j.ces.2022.118179

Betaine-Based Deep Eutectic Solvent as a New Media for Laccase-Catalyzed Template-Guided Polymerization/Copolymerization of Aniline and 3-Aminobenzoic Acid

Irina Vasil’eva, Olga Morozova, Galina Shumakovich and Alexander Yaropolov

IJMS, 2022, 23, 11409
DOI: 10.3390/ijms231911409

Enzymatic Valorization of Lignocellulosic Biomass—The Influence of Deep Eutectic Solvents and Ionic Liquids on the Activity of Cellulolytic Enzymes

Agata Wawoczny, Marta Przypis and Danuta Gillner

Sustainability, 2023, 15, 16726
DOI: 10.3390/su152416726

L-proline-based deep eutectic solvents as green and enantioselective organocatalyst/media for aldol reaction

Stephany Zárate-Roldán, María J. Trujillo-Rodríguez, M. Concepción Gimeno and Raquel P. Herrera

Journal of Molecular Liquids, 2024, 396, 123971
DOI: 10.1016/j.molliq.2024.123971

Nanomole‐scale photochemical thiol‐ene chemistry for high‐throughput late‐stage diversification of peptide macrocycles

Mark D. Nolan, Mischa Schüttel, Eoin M. Scanlan and Alexander L. Nielsen

Peptide Science, 2024, 116
DOI: 10.1002/pep2.24310

Synthesis of Carboranyl Alkyl Sulfide via Radical Thiol–Ene “Click” Reaction

Dinghai Wang, Zhiyong He, Chang Liu, Yuting Wu, Zhongkuan Tang, Siqi Liu, Baolin Yu, Jingwen Luo and Bindong Li

Org. Lett., 2025, 27, 4000
DOI: 10.1021/acs.orglett.5c00959

From Hemp Waste to Bioactive Nanofiber Composites: Deep Eutectic Solvents and Electrospinning in Upcycling Endeavors

Cláudia Mouro, Ana P. Gomes and Isabel C. Gouveia

Gels, 2023, 10, 1
DOI: 10.3390/gels10010001

Natural Deep Eutectic Solvents as Rust Removal Agents from Lithic and Cellulosic Substrates

Francesco Gabriele, Cinzia Casieri and Nicoletta Spreti

Molecules, 2024, 29, 624
DOI: 10.3390/molecules29030624

Regulating defected zirconium metal–organic frameworks in ionic liquid for sewage treatment

Jun-Jie Duan, Xin Xin, Shi-Jie Guo, Shuang-Long Wang, Hao Chen, Jun-Ling Li, Song Qin and Guo-Hong Tao

Journal of Molecular Structure, 2023, 1286, 135607
DOI: 10.1016/j.molstruc.2023.135607

NADES-Assisted Extraction of Polyphenols from Coriander Seeds: A Systematic Optimization Study

Federica Ianni, Samir Scandar, Luciano Mangiapelo, Francesca Blasi, Maria Carla Marcotullio and Lina Cossignani

Antioxidants, 2023, 12, 2048
DOI: 10.3390/antiox12122048

Rethinking the Esterquats: Synthesis, Stability, Ecotoxicity and Applications of Esterquats Incorporating Analogs of Betaine or Choline as the Cation in Their Structure

Marcin Wysocki, Witold Stachowiak, Mikołaj Smolibowski, Adriana Olejniczak, Michał Niemczak and Julia L. Shamshina

IJMS, 2024, 25, 5761
DOI: 10.3390/ijms25115761

Efficient Synthesis of Furfuryl Alcohol from Corncob in a Deep Eutectic Solvent System

Lizhen Qin, Junhua Di and Yucai He

Processes, 2022, 10, 1873
DOI: 10.3390/pr10091873

Recent advances and new trends in the use of deep eutectic solvents in organic synthesis and other applications

Hossein Tavakol and Parvaneh Shafieyoon

Journal of Molecular Liquids, 2025, 428, 127510
DOI: 10.1016/j.molliq.2025.127510

A Mild, Efficient and Sustainable Tetrahydropyranylation of Alcohols Promoted by Acidic Natural Deep Eutectic Solvents

Davide Arnodo, Eugenio De Nardo, Simone Ghinato, Salvatore Baldino, Marco Blangetti and Cristina Prandi

ChemSusChem, 2023, 16
DOI: 10.1002/cssc.202202066

Serine-Modified Au@Cu2O Core–Shell Nanoparticles for Catalysis-Mediated Colorimetric Detection of Small Molecules

Pei-Yu Wang, Wen-Jyng Wang and Wei-Peng Li

ACS Appl. Nano Mater., 2023, 6, 15651
DOI: 10.1021/acsanm.3c02468

Adsorptive Membranes Incorporating Ionic Liquids (ILs), Deep Eutectic Solvents (DESs) or Graphene Oxide (GO) for Metal Salts Extraction from Aqueous Feed

Liyan Qalyoubi, Ioannis Zuburtikudis, Hadil Abu Khalifeh and Enas Nashef

Membranes, 2023, 13, 874
DOI: 10.3390/membranes13110874

Deciphering the structure of deep eutectic solvents: A computational study from the solute's viewpoint

Chiara Sepali, Sulejman Skoko, Luca Guglielmero, Tommaso Giovannini, Andrea Mezzetta, Felicia D'Andrea, Christian Silvio Pomelli, Lorenzo Guazzelli and Chiara Cappelli

Journal of Molecular Liquids, 2024, 399, 124326
DOI: 10.1016/j.molliq.2024.124326

Efficient and green strategy based on pulsed electric field coupled with deep eutectic solvents for recovering flavonoids and preparing flavonoid aglycones from noni-processing wastes

Jian Li, Wen Chen, Debao Niu, Rui Wang, Fei-Yue Xu, Bo-Ru Chen, Jia-Wei Lin, Zhong-Sheng Tang and Xin-An Zeng

Journal of Cleaner Production, 2022, 368, 133019
DOI: 10.1016/j.jclepro.2022.133019

Natural Deep Eutectic Solvents as a Novel Bio-Based Matrix for Ready-to-Use Natural Antioxidants-Enriched Ingredients: Extraction and Formulation Optimization

Leslie Boudesocque-Delaye, Iron Mike Ardeza, Alexis Verger, Roxane Grard, Isabelle Théry-Koné, Xavier Perse and Emilie Munnier

Cosmetics, 2024, 11, 17
DOI: 10.3390/cosmetics11010017

Synergistic two-step modification of polybenzimidazole (PBI) nanofiltration membranes for improved molecular separation in acidic and organic environments

Srinath Ravi, Sung Ju Shin, Saikat Sinha Ray and Young-Nam Kwon

Journal of Industrial and Engineering Chemistry, 2025
DOI: 10.1016/j.jiec.2025.07.048

Preparation of Ammonium Persulfate/Glycerol based Novel Deep Eutectic Solvent under controlled conditions; Characterizations, Physical properties

Shafiq Uz Zaman, Muhammad Shozab Mehdi, Muhammad Umar, Sikander Rafiq, Saif-ur-Rehman, Muhammad Khaliq U Zaman, Muhammad Danish Javed, Muhammad Ahsan Waseem and Nishwana Tahir

Journal of Molecular Structure, 2023, 1283, 135265
DOI: 10.1016/j.molstruc.2023.135265

Challenging DESs and ILs in the valorization of food waste: a case study

Angelica Mero, Nicholas R. Moody, Elena Husanu, Andrea Mezzetta, Felicia D’Andrea, Christian Silvio Pomelli, Nathalie Bernaert, Francesca Paradisi and Lorenzo Guazzelli

Front. Chem., 2023, 11
DOI: 10.3389/fchem.2023.1270221

Switchable Deep Eutectic Solvents for Lignin Dissolution and Regeneration

Debao Li, Letian Qi, Mengru Yang, Yujie Gu, Yu Xue, Jiachuan Chen, Ming He and Guihua Yang

Polymers, 2023, 15, 4233
DOI: 10.3390/polym15214233

Unlocking the Potential of Deep Eutectic Solvents and Ligand‐to‐Metal Charge Transfer Processes: A Reusable Iron‐and‐UV‐Based System for Sustainable C−C Bond Formation

Nerea González‐Gallardo, Alejandro Cores, Xavier Marset, Néstor Guijarro, Gabriela Guillena and Diego J. Ramón

ChemSusChem, 2024, 17
DOI: 10.1002/cssc.202400911

Phase equilibrium and kinetic studies of choline chloride-based deep eutectic solvents in water system for the inhibition of methane gas hydrate formation

Aliyu Adebayo Sulaimon, Ali Qasim, Mohamad Athif, Asiah Nusaibah Masri, Pearl Isabellah Murungi and Aneel Jordan Atthi Tasan Singh

Journal of Ionic Liquids, 2025, 5, 100127
DOI: 10.1016/j.jil.2024.100127

Dissolution of Metals (Cu, Fe, Pb, and Zn) from Different Metal-Bearing Species (Sulfides, Oxides, and Sulfates) Using Three Deep Eutectic Solvents Based on Choline Chloride

Carlos F. Aragón-Tobar, Diana Endara and Ernesto de la Torre

Molecules, 2024, 29, 290
DOI: 10.3390/molecules29020290

Visible‐Light‐Mediated Amide Synthesis in Deep Eutectic Solvents

Debora Procopio, Xavier Marset, Gabriela Guillena, Maria Luisa Di Gioia and Diego J. Ramón

Adv Synth Catal, 2024, 366, 870
DOI: 10.1002/adsc.202300725

Traceless Thioacid-Mediated Radical Cyclization of 1,6-Dienes

Dylan M. Lynch, Mark D. Nolan, Conor Williams, Leendert Van Dalsen, Susannah H. Calvert, Fabrice Dénès, Cristina Trujillo and Eoin M. Scanlan

J. Org. Chem., 2023, 88, 10020
DOI: 10.1021/acs.joc.3c00824

A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest

Cátia Ferreira and Mafalda Sarraguça

Pharmaceuticals, 2024, 17, 124
DOI: 10.3390/ph17010124

Green hydrophobic deep eutectic solvents as low-viscosity and efficient lubricants

Yuting Li, Cheng Cao, Meng Cai, Hao Li, Xiaoqiang Fan, Yu Gao, Zhibin Lu and Minhao Zhu

Tribology International, 2023, 185, 108531
DOI: 10.1016/j.triboint.2023.108531

CO2 Capture Using Deep Eutectic Solvents Integrated with Microalgal Fixation

Eliza Gabriela Brettfeld, Daria Gabriela Popa, Tănase Dobre, Corina Ioana Moga, Diana Constantinescu-Aruxandei and Florin Oancea

Clean Technol., 2023, 6, 32
DOI: 10.3390/cleantechnol6010003

Temperature Effects on Physiochemical Characteristics of Sugar-Based Natural Deep Eutectic Solvents

Mohammad Tarikuzzaman, Viral Sagar, Mark James Wong, Joan G. Lynam and Hilda Elizabeth Reynel-Avila

Advances in Materials Science and Engineering, 2024, 2024, 1
DOI: 10.1155/2024/6641317

Application of Choline Chloride-Based Deep Eutectic Solvents in the Synthesis of Hydrazones

Valentina Bušić, Sunčica Roca and Dajana Gašo-Sokač

Separations, 2023, 10, 551
DOI: 10.3390/separations10110551