Sesamin improved growth and overall health in young animals by enhancing gut–liver axis function

Chen Chen, Min Qi, Zhiran Xu, Jincheng Wen, Wenjie Tang, Hui Diao, Zhangcheng Li, Yunyun Chu, Fu Feng and Zhiru Tang

Food Funct., 2025, 16, 4415
DOI: 10.1039/D4FO05933F

Wheat peptides inhibit the activation of MAPK and NF-κB inflammatory pathways and maintain epithelial barrier integrity in NSAID-induced intestinal epithelial injury

Zhiyuan Feng, Ying Wei, Zhuoran Zhang, Mingliang Li, Ruizeng Gu, Lu Lu, Wenying Liu and Huimin Qin

Food Funct., 2024, 15, 823
DOI: 10.1039/D3FO03954D

Dietary 5-demethylnobiletin attenuated dextran sulfate sodium-induced colitis in mice by inhibiting immune response and regulating gut microbiota

Peichun Xie, Bin Chen, Jiaxin Ran, Minmin Zhan, Hengjun Du, Fengyi Hong, Muwen Lu, Yong Cao, Hang Xiao and Mingyue Song

Food Funct., 2023, 14, 6248
DOI: 10.1039/D3FO01095C

Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism

Juan Ma, Yin Wan, Lingmin Song, Luchen Wang, Huimei Wang, Yingzhi Li and Danfei Huang

Part Fibre Toxicol, 2023, 20
DOI: 10.1186/s12989-023-00560-8

Anti-inflammatory and gut microbiota regulatory effects of walnut protein derived peptide LPF in vivo

Tongxin Zhi, Dan Hong, Zijie Zhang, Siting Li, Junxia Xia, Chong Wang, Yongling Wu, Yingmin Jia and Aijin Ma

Food Research International, 2022, 152, 110875
DOI: 10.1016/j.foodres.2021.110875

Sesamin Alleviates Allergen-Induced Diarrhea by Restoring Gut Microbiota Composition and Intestinal Barrier Function

Yu Li, Fan Wu, Yongli Wang, Bo Li, Pranesha Prabhakaran, Wenbo Zhou, Yu Han, Dongxiao Sun-Waterhouse, Dapeng Li and Feng Li

J. Agric. Food Chem., 2025, 73, 1965
DOI: 10.1021/acs.jafc.4c10158

Effects of Centella asiatica-isolated pectic polysaccharide on dextran sulfate sodium-induced colitis

Hyun Young Shin, Won Bi Jeong, Mi Yeun Joung, Kwang-Soon Shin and Kwang-Won Yu

International Journal of Biological Macromolecules, 2025, 285, 138237
DOI: 10.1016/j.ijbiomac.2024.138237

Morin alleviates DSS-induced ulcerative colitis in mice via inhibition of inflammation and modulation of intestinal microbiota

Li Qiu, Chengqiu Yan, Yue Yang, Kunjian Liu, Yu Yin, Yiwen Zhang, Yuting Lei, Xiangwen Jia and Guofeng Li

International Immunopharmacology, 2024, 140, 112846
DOI: 10.1016/j.intimp.2024.112846

Glycerol monolaurate ameliorates DSS-induced acute colitis by inhibiting infiltration of Th17, neutrophils, macrophages and altering the gut microbiota

Ke-Jie He, Jia-Hui Dong, Xiao-Mei Ouyang, Ya-Ni Huo, Xiao-Shen Cheng, Ying Lin, Yue Li, Guoyu Gong, Jingjing Liu, Jian-Lin Ren and Bayasi Guleng

Front. Nutr., 2022, 9
DOI: 10.3389/fnut.2022.911315

Phytochemicals and Regulation of NF-kB in Inflammatory Bowel Diseases: An Overview of In Vitro and In Vivo Effects

Lucas Fornari Laurindo, Ana Rita de Oliveira dos Santos, Antonelly Cassio Alves de Carvalho, Marcelo Dib Bechara, Elen Landgraf Guiguer, Ricardo de Alvares Goulart, Renata Vargas Sinatora, Adriano Cressoni Araújo and Sandra Maria Barbalho

Metabolites, 2023, 13, 96
DOI: 10.3390/metabo13010096

4-hydroxysesamin protects rat with right ventricular failure due to pulmonary hypertension by inhibiting JNK/p38 MAPK signaling

Lingnan Zhang and Xinshun Gu

Aging, 2024
DOI: 10.18632/aging.205808

Cod (Gadus) skin collagen peptide powder reduces inflammation, restores mucosal barrier function, and inhibits fibrosis in dextran sodium sulfate-induced colitis in mice

Xiangyu Guo, Xiangdan Li, Yanru Dong, Wei Xie, Toufeng Jin, Dongyuan Xu and Lan Liu

Journal of Ethnopharmacology, 2023, 316, 116728
DOI: 10.1016/j.jep.2023.116728

Sesamin inhibits RANKL‐induced osteoclastogenesis and attenuates LPS‐induced osteolysis via suppression of ERK and NF‐κB signalling pathways

Xiaolong Yu, Jiawei Hu, Xinming Yang, Qiang Xu, Hangjun Chen, Ping Zhan and Bin Zhang

J Cellular Molecular Medi, 2024, 28
DOI: 10.1111/jcmm.18056

Bioassay-guided isolation of sesamin and fargesin from the hydroalcoholic stem extract of Zanthoxylum armatum DC. inhibited inflammation in CpG-stimulated conventional type 1 dendritic cells

Ningthoujam Indrajit Singh, Chayan Mukherjee, Jerina Soibam, Wangkheimayum Marjit Singh, Naresh Chandra Bal, Sunil Kumar Raghav and Chingakham Brajakishor Singh

Front. Pharmacol., 2025, 16
DOI: 10.3389/fphar.2025.1687789

Revealing therapeutic targets and drugs from Chinese medicine for ulcerative colitis using bioinformatics

Feng Xu, Xiaofen Li, Xiangpei Wang, Hongmei Wu, Song Chen, Jianyang Chen, Xiangxi Kong and Zhenglin Yang

Journal of Biomolecular Structure and Dynamics, 2026, 44, 929
DOI: 10.1080/07391102.2024.2440651

Fufang Tongye Shaoshang You repairs ulcerative colitis in mice caused by DSS based on the balanced strategy of "inflammation inhibition–microbiota regulation–mucosa protection"

Yuting Lu, Yuping Dai, Yan Duan, Xiaoting Ni, Juan Li, Qiang Wang, Pei Cai and Shunxiang Li

Journal of Ethnopharmacology, 2026, 367, 121686
DOI: 10.1016/j.jep.2026.121686

Aspergillus cristatus attenuates DSS‐induced intestinal barrier damage through reducing the oxidative stress, regulating short‐chain fatty acid and inhibiting MAPK signaling pathways

Xin Wang, Xuejun Zeng, Xiao Zhang, Jianping Wei, Yuxiang Zhang, Fangyu Long, Tianli Yue and Yahong Yuan

J Sci Food Agric, 2023, 103, 1736
DOI: 10.1002/jsfa.12334

Luteolin ameliorates DSS-induced colitis in mice via suppressing macrophage activation and chemotaxis

Liwei Xue, Xiaosheng Jin, Tingting Ji, Rongzhou Li, Xiaoju Zhuge, Fang Xu, Zijiao Quan, Haibin Tong and Weilai Yu

International Immunopharmacology, 2023, 124, 110996
DOI: 10.1016/j.intimp.2023.110996

Rehmannia glutinosa polysaccharides attenuates colitis via reshaping gut microbiota and short‐chain fatty acid production

Hao Lv, Hongpeng Jia, Wenjie Cai, Rujing Cao, Chenyu Xue and Na Dong

J Sci Food Agric, 2023, 103, 3926
DOI: 10.1002/jsfa.12326

Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An in vitro and in vivo Studies

Shengwei Chen, Yi Zhang, Xueting Niu, Sahar Ghulam Mohyuddin, Jiayin Wen, Minglong Bao, Tianyue Yu, Lianyun Wu, Canyin Hu, Yanhong Yong, Xiaoxi Liu, A. M. Abd El-Aty and Xianghong Ju

Front. Nutr., 2021, 8
DOI: 10.3389/fnut.2021.748118

Sesamin Activates Nrf2/Cnc-Dependent Transcription in the Absence of Oxidative Stress in Drosophila Adult Brains

Tuan Dat Le and Yoshihiro H. Inoue

Antioxidants, 2021, 10, 924
DOI: 10.3390/antiox10060924

Effect of Fermented Foods on Inflammatory Bowel Disease: A Focus on the MAPK and NF-kβ Pathways

Ramses Cruz-Valencia, Lourdes Santiago-López, Luis Mojica, Adrián Hernández-Mendoza, Belinda Vallejo-Cordoba, Sonia G. Sáyago-Ayerdi, Lilia M. Beltrán-Barrientos and Aarón F. González-Córdova

ACS Food Sci. Technol., 2025, 5, 398
DOI: 10.1021/acsfoodscitech.4c00628

Cannabis sativa alleviates experimentally acetic acid- induced ulcerative colitis in rats: targeting CB1/SIRT/MAPK signaling pathways

Rania Elgohary, Enayat A. Omara and Abeer Salama

Immunopharmacology and Immunotoxicology, 2025, 47, 120
DOI: 10.1080/08923973.2024.2445733

Sesamin ameliorates ulcerative colitis by modulating the DUSP1/ERK feedback loop and restoring gut microbiota homeostasis

Shuxia Cao, Xiangyu Guo, Mengyuan Xin, Xin Wang, Jiaqi Huo, Yuyang Yue, Xiangdan Li, Dongyuan Xu and Lan Liu

Phytomedicine, 2025, 147, 157188
DOI: 10.1016/j.phymed.2025.157188

Ponicidin-induced conformational changes of HSP90 regulates the MAPK pathway to relieve ulcerative colitis

Xuerong Zhang, Yuanhang Xu, Minqi Fan, Xueqing Lv, Jiachan Long, Rong Yang, Rong Zhang, Zhongqiu Liu, Jiangyong Gu, Peng Wu and Caiyan Wang

Journal of Ethnopharmacology, 2024, 321, 117483
DOI: 10.1016/j.jep.2023.117483

Aesculetin exhibited anti-inflammatory activities through inhibiting NF-кB and MAPKs pathway in vitro and in vivo

Shou-Kai Wang, Ting-Xiao Chen, Wei Wang, Ling-Ling Xu, Yu-Qing Zhang, Zhen Jin, You-Bin Liu and You-Zhi Tang

Journal of Ethnopharmacology, 2022, 296, 115489
DOI: 10.1016/j.jep.2022.115489

Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms

Chaoying Zhu, Yuan Gao, Haiying Gong and Jiabo Wang

Chin Med, 2026, 21
DOI: 10.1186/s13020-026-01340-0