Issue 6, 2019

Advances in diagnostic methods for keloids and biomarker-targeted fluorescent probes

Abstract

A keloid is a type of unusually raised scar. Unlike other raised scars, keloids form larger sizes than the wound site due to overgrowth, generally related to various biological factors. To date, only a few diagnostic and therapeutic methods for keloids have been reported. The high recurrence rates and undesirable side effects of keloids, at the end stage, encourage the invention of novel diagnostic tools, in order to cure keloids at an earlier stage. In this review, we summarize the general information about keloid diagnosis, keloid biomarkers, and recently reported fluorescent probes that can sense the key biomarkers of keloids. The focused description of fluorescent probes for keloid biomarkers and the author's perspective give useful insights in order to design the next-generation diagnostic sensing system for keloids.

Graphical abstract: Advances in diagnostic methods for keloids and biomarker-targeted fluorescent probes

Article information

Article type
Minireview
Submitted
14 Des. 2018
Accepted
20 Jan. 2019
First published
25 Jan. 2019

Analyst, 2019,144, 1866-1875

Advances in diagnostic methods for keloids and biomarker-targeted fluorescent probes

S. Kang, J. K. Hur and D. Kim, Analyst, 2019, 144, 1866 DOI: 10.1039/C8AN02421A

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