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Correction: Discovery of dibenzylbutane lignan LCA derivatives as potent anti-inflammatory agents

Zhen Wang b, Juan Zhang b, Conghao Gai a, Jing Wang a, Xiaobin Zhuo a, Yan Song c, Yan Zou a, Peichao Zhang a, Guige Hou d, Qingguo Meng *b, Qingjie Zhao *a and Xiaoyun Chai *a
aDepartment of Organic Chemistry, School of Pharmacy, Naval Medical University, Shanghai 200433, China. E-mail: qjzhao_325@126.com; chaixy1207@163.com
bSchool of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Yantai University, Yantai 264005, China. E-mail: zhenwang0703@163.com; qinggmeng@163.com
cNavy Medical Center, Naval Medical University, Shanghai 200433, China
dSchool of Pharmacy, Binzhou Medical University, Yantai 264003, China

Received 3rd June 2024 , Accepted 3rd June 2024

First published on 17th June 2024


Abstract

Correction for ‘Discovery of dibenzylbutane lignan LCA derivatives as potent anti-inflammatory agents’ by Zhen Wang et al., RSC Med. Chem., 2024, https://doi.org/10.1039/d4md00053f.


There was an error in the structural configuration of the compound LCA and its derivatives shown in Fig. 1 and Scheme 1.

Fig. 1 should appear as follows:


image file: d4md90023e-f1.tif
Fig. 1 Design of target compounds.

Scheme 1 should appear as follows:


image file: d4md90023e-s1.tif
Scheme 1 Synthesis of target compounds. Reagents and conditions: (a) sulfuric acid, MeOH, reflux, 5 h; (b) H2, Pd/C, MeOH, rt, 10 h; (c) benzyl bromide, K2CO3, acetone, reflux, 5 h; (d) NaOH, MeOH, reflux, 3 h; (e) (S)-4-benzyloxazolidin-2-one, N,N-dicyclohexylcarbodiimide, 4-dimethylaminopyridine, CH2Cl2, rt, 12 h; (f) lithium diisopropylamide, iodobenzene diacetate, tetrahydrofuran, −78 °C, 2 h; (g) lithium hydroxide monohydrate, H2O2, tetrahydrofuran, H2O, 0 °C, 15 min, then rt, 12 h; (h) O-benzotriazole-N,N,N′,N′-tetramethyl-uronium-hexafluoro-phosphate, N,N-diisopropylethylamine, N,N-dimethylformamide, rt, 4 h; (i) H2, Pd/C, MeOH, rt, 3 h.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


Footnote

These authors contributed equally to this work.

This journal is © The Royal Society of Chemistry 2024
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