Issue 44, 2021

Reactions involving aryl methyl ketone and molecular iodine: a powerful tool in the one-pot synthesis of heterocycles

Abstract

The preparation of heterocyclic compounds has attracted great attention in organic chemistry because of their extensive application in the field of bioactive molecules, materials science, and natural products. Accordingly, the straightforward design and synthesis of heterocycles using readily accessible starting materials and reagents are among the main targets of synthetic chemists. In this context, reactions involving aryl methyl ketone and molecular iodine are recognized as powerful approaches for one-pot synthesis of heterocyclic compounds. This review focuses on the approaches developed for one-pot synthesis of N,O,S,Se-heterocyclic compounds through reactions involving aryl methyl ketone and molecular iodine over the past ten years.

Graphical abstract: Reactions involving aryl methyl ketone and molecular iodine: a powerful tool in the one-pot synthesis of heterocycles

Article information

Article type
Perspective
Submitted
24 Jul. 2021
Accepted
14 Okt. 2021
First published
14 Okt. 2021

New J. Chem., 2021,45, 20486-20518

Reactions involving aryl methyl ketone and molecular iodine: a powerful tool in the one-pot synthesis of heterocycles

S. Rajai-Daryasarei, M. H. Gohari and N. Mohammadi, New J. Chem., 2021, 45, 20486 DOI: 10.1039/D1NJ03572J

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