Issue 32, 2021

4-Chloro-3-formylcoumarin as a multifaceted building block for the development of various bio-active substituted and fused coumarin heterocycles: a brief review

Abstract

This paper reviews the research data available in the literature on the chemistry of 4-chloro-3-formylcoumarins reported over the last two to three decades. It covers the synthetic applicability of 4-chloro-3-formylcoumarins in the development of 3,4-substituted coumarins as well as 5-, 6- and 7-membered ring fused coumarin derivatives via classical reaction protocols, microwave-mediated reactions, organo-catalyzed reactions, transition metal-catalyzed reactions, and green reaction protocols.

Graphical abstract: 4-Chloro-3-formylcoumarin as a multifaceted building block for the development of various bio-active substituted and fused coumarin heterocycles: a brief review

Article information

Article type
Perspective
Submitted
04 Jun. 2021
Accepted
29 Jun. 2021
First published
01 Jul. 2021

New J. Chem., 2021,45, 14269-14327

4-Chloro-3-formylcoumarin as a multifaceted building block for the development of various bio-active substituted and fused coumarin heterocycles: a brief review

P. Patra, New J. Chem., 2021, 45, 14269 DOI: 10.1039/D1NJ02755G

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