Hydrofluorocarbon nanoparticles for 19F MRI-fluorescence dual imaging and chemo-photodynamic therapy

Tingjuan Wu, Kexin Chen, Mou Jiang, Anfeng Li, Xingxing Peng, Shizhen Chen, Zhigang Yang, Xin Zhou, Xing Zheng and Zhong-Xing Jiang

Org. Biomol. Chem., 2022, 20, 1299
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Synthesis of trifluoromethylated aza-BODIPYs as fluorescence-19F MRI dual imaging and photodynamic agents

Anfeng Li, Xingxing Peng, Mou Jiang, Tingjuan Wu, Kexin Chen, Zhigang Yang, Shizhen Chen, Xin Zhou, Xing Zheng and Zhong-Xing Jiang

Org. Biomol. Chem., 2022, 20, 3335
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Spatial characterization of redox processes and speciation of Ru(iii) anticancer complexes by 19F magnetic resonance imaging

Gregory A. MacNeil, Stephanie W. Chang, Kathleen E. Prosser, Eric Ye, Devon Heroux, Andrew R. Lewis, Marcel Bally and Charles J. Walsby

Chem. Commun., 2023, 59, 623
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[Cu(NHC)(OR)] (R = C(CF3)3) complexes for N–H and S–H bond activation and as pre-catalysts in the Chan–Evans–Lam reaction

Tommaso Ruggiero, Kristof Van Hecke, Catherine S. J. Cazin and Steven P. Nolan

Dalton Trans., 2025, 54, 1329
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General access to furan-substituted gem-difluoroalkenes enabled by PFTB-promoted cross-coupling of ene-yne-ketones and difluorocarbene

Na Li, Chenghui Li, Qianying Zhou, Xin Zhang, Zhouming Deng, Zhong-Xing Jiang and Zhigang Yang

Chem. Sci., 2025, 16, 1455
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Probing rotaxane dynamics with 19F NMR/MRI: Unveiling the roles of mechanical bond and steric hindrance

Yu Li, Man Luo, Mou Jiang, Rui Zhou, Wanrong Yang, Shenhui Li, Fang Wang, Lijun Zhu, Pei He, Minghui Yang, Xin Zhou, Zhong-Xing Jiang and Shizhen Chen

Analytica Chimica Acta, 2024, 1319, 342983
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Selective radical-type perfluoro-tert-butylation of unsaturated compounds with a stable and scalable reagent

Ruitong Zhang, Shengqi Zhou, Yijing Li, Yaxing Wu, Xiangyu Chen, Fei Wang, Yunchen Jiang, Xingwei Guo and Chao Chen

Nat Commun, 2025, 16
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Fluorinated albumin nanoplatform for 19F MRI-guided synergistic chemo-chemodynamic therapy and immune activation in breast cancer

Lijun Zhu, Tingjuan Wu, Yu Li, Xingxing Peng, Anfeng Li, Fang Wang, Pei He, Xin Zhou, Shizhen Chen and Zhong-Xing Jiang

Journal of Controlled Release, 2025, 386, 114098
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Self‐Assembly and Biological Properties of Highly Fluorinated Oligonucleotide Amphiphiles

Quentin Laurent, Beatrice L. Bona, Jathavan Asohan, Marta Rosati, Sinan Faiad, Francesca Baldelli Bombelli, Pierangelo Metrangolo and Hanadi F. Sleiman

Angew Chem Int Ed, 2025, 64
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Nanotechnology as a Versatile Tool for 19F-MRI Agent’s Formulation: A Glimpse into the Use of Perfluorinated and Fluorinated Compounds in Nanoparticles

Joice Maria Joseph, Maria Rosa Gigliobianco, Bita Mahdavi Firouzabadi, Roberta Censi and Piera Di Martino

Pharmaceutics, 2022, 14, 382
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Perfluoro‐tert‐butyl Group‐Derived Capmatinib: Synthesis, Biological Evaluation and Its Application in 19F Magnetic Resonance Imaging

Xinnan Zhang, Luting Wang, Ruimin Huang, Jingbo Wang and Qifan Yan

ChemBioChem, 2023, 24
DOI: 10.1002/cbic.202300354

Fluorinated macromolecular amphiphiles as prototypic molecular drones

Yujie Zheng, Lijun Zhu, Changsheng Ke, Yu Li, Zhiwen Zhou, Mou Jiang, Fang Wang, Pei He, Xin Zhou, Zhong-Xing Jiang and Shizhen Chen

Proc. Natl. Acad. Sci. U.S.A., 2024, 121
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19F MRI-fluorescence imaging dual-modal cell tracking with partially fluorinated nanoemulsions

Ting Tang, Qiang Zhu, Shuang Liu, Hailong Dai, Yu Li, Caihong Tang, Kexin Chen, Mou Jiang, Lijun Zhu, Xin Zhou, ShiZhen Chen, Zitong Zheng and Zhong-Xing Jiang

Front. Bioeng. Biotechnol., 2022, 10
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Synthesis and Detection of BODIPY‐, Biotin‐, and 19F‐ Labeled Single‐Entity Dendritic Heparan Sulfate Mimetics

Sam Spijkers‐Shaw, Rory Devlin, Nicholas J. Shields, Xiang Feng, Tessa Peck, Georgia Lenihan‐Geels, Connor Davis, Sarah L. Young, Anne C. La Flamme and Olga V. Zubkova

Angew Chem Int Ed, 2024, 63
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19F Barcoding Enables Multiplex Detection of Biomarkers Associated with Organ Injury and Cancer

Xiangjie Luo, Bilun Kang, Xiaoqin Chi, Hui Xiong, Dongxia Chen, Yifan Fan, Lingxuan Li, Limin Chen, Ao Li, Jinhao Gao and Hongyu Lin

Angewandte Chemie, 2022, 134
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Multibranched-Based Fluorinated Materials: Tailor-Made Design of 19F-MRI Probes

Beatrice Lucia Bona, Olga Koshkina, Cristina Chirizzi, Valentina Dichiarante, Pierangelo Metrangolo and Francesca Baldelli Bombelli

Acc. Mater. Res., 2023, 4, 71
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Partially fluorinated nanoemulsions for 19F MRI-fluorescence dual imaging cell tracking

Kexin Chen, Tingjuan Wu, Mou Jiang, Anfeng Li, Xingxing Peng, Shizhen Chen, Zhigang Yang, Xin Zhou, Xing Zheng and Zhong-Xing Jiang

Colloids and Surfaces B: Biointerfaces, 2022, 215, 112493
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Mechanical Interlocking of 144 Symmetrical 19F and Tetraphenylethylene for Magnetic Resonance-Fluorescence Dual Imaging

Lan Yang, Fang Wang, Yu Li, Rui Zhou, Anfeng Li, Tingjuan Wu, Maosong Qiu, Lei Zhang, Minghui Yang, Xin Zhou, Zhong-Xing Jiang and Shizhen Chen

J. Am. Chem. Soc., 2025, 147, 7137
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Detection and identification of amphetamine-type stimulants and analogs via recognition-enabled “chromatographic” 19F NMR

Jiayu Jiang, Lixian Wen, Hongshuang Wang, Xiaoguang Chen, Yanchuan Zhao and Xiaohui Wang

Journal of Fluorine Chemistry, 2023, 266, 110085
DOI: 10.1016/j.jfluchem.2023.110085

Small Molecule Probes for 19F Magnetic Resonance Imaging

Ao Li, Xiangjie Luo, Dongxia Chen, Lingxuan Li, Hongyu Lin and Jinhao Gao

Anal. Chem., 2023, 95, 70
DOI: 10.1021/acs.analchem.2c04539

Fluorinated [2]rotaxanes as sensitive 19F MRI agents: Threading for higher sensitivity

Lan Yang, Yu Li, Mou Jiang, Rui Zhou, Hengjiang Cong, Minghui Yang, Lei Zhang, Shenhui Li, Yunhuang Yang, Maili Liu, Xin Zhou, Zhong-Xing Jiang and Shizhen Chen

Chinese Chemical Letters, 2024, 35, 109512
DOI: 10.1016/j.cclet.2024.109512

Self‐Assembly and Biological Properties of Highly Fluorinated Oligonucleotide Amphiphiles

Quentin Laurent, Beatrice L. Bona, Jathavan Asohan, Marta Rosati, Sinan Faiad, Francesca Baldelli Bombelli, Pierangelo Metrangolo and Hanadi F. Sleiman

Angewandte Chemie, 2025, 137
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19F MRI Probes for Multimodal Imaging**

Dawid Janasik and Tomasz Krawczyk

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202102556

Magnetic Particle Imaging: From Tracer Design to Biomedical Applications in Vasculature Abnormality

Xulin Xie, Jiao Zhai, Xiaoyu Zhou, Zhengjun Guo, Pui‐Chi Lo, Guangyu Zhu, Kannie W. Y. Chan and Mengsu Yang

Advanced Materials, 2024, 36
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Self-Assembly of Precisely Fluorinated Albumin for Dual Imaging-Guided Synergistic Chemo–Photothermal–Photodynamic Cancer Therapy

Lijun Zhu, Yu Li, Mou Jiang, Changsheng Ke, Hanxiong Long, Maosong Qiu, Lei Zhang, Chaohui Ye, Xin Zhou, Zhong-Xing Jiang and Shizhen Chen

ACS Appl. Mater. Interfaces, 2023, 15, 2665
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Unraveling the Stability and Magnetic Properties of Bis-Hydrated Mn(II) Complexes via Tailored Ligand Design

Niharika Keot and Manabendra Sarma

J. Phys. Chem. A, 2024, 128, 8346
DOI: 10.1021/acs.jpca.4c03053

19F Barcoding Enables Multiplex Detection of Biomarkers Associated with Organ Injury and Cancer

Xiangjie Luo, Bilun Kang, Xiaoqin Chi, Hui Xiong, Dongxia Chen, Yifan Fan, Lingxuan Li, Limin Chen, Ao Li, Jinhao Gao and Hongyu Lin

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202211189

Visualizing enterohepatic circulation in vivo by sensitive 19F MRI with a fluorinated ferrous chelate-based small molecule probe

Lingxuan Li, Ao Li, Junjie Wang, Juan Shao, Huijie Zhou, Zixiong Peng, Hongyu Lin and Jinhao Gao

Biomaterials, 2025, 317, 123073
DOI: 10.1016/j.biomaterials.2024.123073

Fluorinated Human Serum Albumin as Potential 19F Magnetic Resonance Imaging Probe

Dmitry E. Mitin and Alexey S. Chubarov

Molecules, 2023, 28, 1695
DOI: 10.3390/molecules28041695

Design of fluorinated stealth poly(ε-caprolactone) nanocarriers

Beatrice Lucia Bona, Prescillia Lagarrigue, Cristina Chirizzi, Maria Isabel Martinez Espinoza, Christian Pipino, Pierangelo Metrangolo, Francesco Cellesi and Francesca Baldelli Bombelli

Colloids and Surfaces B: Biointerfaces, 2024, 234, 113730
DOI: 10.1016/j.colsurfb.2023.113730

Synthesis and Detection of BODIPY‐, Biotin‐, and 19F‐ Labeled Single‐Entity Dendritic Heparan Sulfate Mimetics

Sam Spijkers‐Shaw, Rory Devlin, Nicholas J. Shields, Xiang Feng, Tessa Peck, Georgia Lenihan‐Geels, Connor Davis, Sarah L. Young, Anne C. La Flamme and Olga V. Zubkova

Angewandte Chemie, 2024, 136
DOI: 10.1002/ange.202316791