Stereorandomized Oncocins with Preserved Ribosome Binding and Antibacterial Activity

Bee Ha Gan, Etienne Bonvin, Thierry Paschoud, Hippolyte Personne, Jérémie Reusser, Xingguang Cai, Robert Rauscher, Thilo Köhler, Christian van Delden, Norbert Polacek and Jean-Louis Reymond

J. Med. Chem., 2024, 67, 19448
DOI: 10.1021/acs.jmedchem.4c01768

Current synthetic chemistry towards cyclic antimicrobial peptides

Tong He, Rui Qu and Jinqiang Zhang

Journal of Peptide Science, 2022, 28
DOI: 10.1002/psc.3387

The Mystery of Homochirality on Earth

Michael G. Weller

Life, 2024, 14, 341
DOI: 10.3390/life14030341

Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space

Etienne Bonvin, Markus Orsi, Thierry Paschoud, Ashvin Gopalasingam, Jérémie Reusser, Thilo Köhler, Christian van Delden and Jean‐Louis Reymond

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202501299

A symmetric chiral aromatic polyamide modified silica material combining rigid-flexible and application in liquid chromatography

Yongli Wu, Yuanyuan Li, Lan Ma, Yulong Ma, Wenxin Ji and Yonggang Sun

Microchemical Journal, 2024, 205, 111284
DOI: 10.1016/j.microc.2024.111284

An intrinsically disordered antimicrobial peptide dendrimer from stereorandomized virtual screening

Xingguang Cai, Markus Orsi, Alice Capecchi, Thilo Köhler, Christian van Delden, Sacha Javor and Jean-Louis Reymond

Cell Reports Physical Science, 2022, 3, 101161
DOI: 10.1016/j.xcrp.2022.101161

To Fold or Not to Fold: Diastereomeric Optimization of an α-Helical Antimicrobial Peptide

Hippolyte Personne, Thierry Paschoud, Sofia Fulgencio, Stéphane Baeriswyl, Thilo Köhler, Christian van Delden, Achim Stocker, Sacha Javor and Jean-Louis Reymond

J. Med. Chem., 2023, 66, 7570
DOI: 10.1021/acs.jmedchem.3c00460

Machine Learning Guided Discovery of Non‐Hemolytic Membrane Disruptive Anticancer Peptides

Elena Zakharova, Markus Orsi, Alice Capecchi and Jean‐Louis Reymond

ChemMedChem, 2022, 17
DOI: 10.1002/cmdc.202200291

Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis

Hippolyte Personne, Thissa N. Siriwardena, Sacha Javor and Jean-Louis Reymond

ACS Omega, 2023, 8, 5050
DOI: 10.1021/acsomega.2c07861

Antimicrobial Peptide–Peptoid Hybrids with and without Membrane Disruption

Etienne Bonvin, Hippolyte Personne, Thierry Paschoud, Jérémie Reusser, Bee-Ha Gan, Alexandre Luscher, Thilo Köhler, Christian van Delden and Jean-Louis Reymond

ACS Infect. Dis., 2023, 9, 2593
DOI: 10.1021/acsinfecdis.3c00421

Antimicrobial Peptide‐Peptoid Macrocycles from the Polymyxin B2 Chemical Space

Etienne Bonvin, Markus Orsi, Thierry Paschoud, Ashvin Gopalasingam, Jérémie Reusser, Thilo Köhler, Christian van Delden and Jean‐Louis Reymond

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202501299