Issue 33, 2022

Stimuli-responsive spin crossover nanoparticles for drug delivery and DNA-binding studies

Abstract

Aminated silica hybrid, spin-crossover (SCO) nanoparticles (AmNPs) coupled with (S)-naproxen (NAP) were proposed for potential drug nanocarriers through drug release experiments at various pH values. DNA- and albumin-binding studies were also carried out using diverse techniques in order to investigate the interaction of the nanoparticles with calf-thymus DNA and serum albumins and to determine the corresponding binding constants.

Graphical abstract: Stimuli-responsive spin crossover nanoparticles for drug delivery and DNA-binding studies

Supplementary files

Article information

Article type
Communication
Submitted
15 Cax 2022
Accepted
25 Qad 2022
First published
03 Leq 2022

Dalton Trans., 2022,51, 12427-12431

Stimuli-responsive spin crossover nanoparticles for drug delivery and DNA-binding studies

C. D. Polyzou, P. Gkolfi, C. T. Chasapis, V. Bekiari, A. Zianna, G. Psomas, M. Ondrej and V. Tangoulis, Dalton Trans., 2022, 51, 12427 DOI: 10.1039/D2DT01509A

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