Issue 7, 2019

A fast-response and highly specific Si-Rhodamine probe for endogenous peroxynitrite detection in living cells

Abstract

Peroxynitrite (ONOO) is involved in a variety of physiological and pathological processes. We designed and synthesized a fluorescent probe SiNH based on Si-rhodamine. The nanoprobe SiNH encapsulated within the amphiphilic copolymer exhibited fast response within 10 s, and it was highly specific for ONOO in aqueous solution. It is demonstrated that the nanoprobe SiNH is applicable for real-time tracing of endogenous ONOO in living cells.

Graphical abstract: A fast-response and highly specific Si-Rhodamine probe for endogenous peroxynitrite detection in living cells

  • This article is part of the themed collection: New Talent

Supplementary files

Article information

Article type
Paper
Submitted
06 Qad 2018
Accepted
30 Qad 2018
First published
30 Qad 2018

Org. Biomol. Chem., 2019,17, 1875-1880

A fast-response and highly specific Si-Rhodamine probe for endogenous peroxynitrite detection in living cells

J. Tang, Q. Li, Z. Guo and W. Zhu, Org. Biomol. Chem., 2019, 17, 1875 DOI: 10.1039/C8OB01598H

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