Issue 7, 2015

A challenging Heck reaction of maleimides

Abstract

Maleimides are extremely susceptible to basic hydrolysis and gave poor yields under Heck conditions. The longstanding problem is solved with the use of a weak base KOAc in a carbonate solvent.

Graphical abstract: A challenging Heck reaction of maleimides

Supplementary files

Article information

Article type
Research Article
Submitted
13 Qun 2015
Accepted
15 Agd 2015
First published
16 Agd 2015

Org. Chem. Front., 2015,2, 775-777

Author version available

A challenging Heck reaction of maleimides

L. H. Lim and J. (. Zhou, Org. Chem. Front., 2015, 2, 775 DOI: 10.1039/C5QO00015G

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