Issue 39, 2013

Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

Abstract

An efficient organocatalyzed strategy for the synthesis of 3-amino-1-indanols has been developed. This method is complementary to the conventional Friedel–Crafts strategy. It is also applicable to the synthesis of enantioenriched 3-amino-1-indanols.

Graphical abstract: Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

Supplementary files

Article information

Article type
Communication
Submitted
29 Way 2012
Accepted
02 Xim 2012
First published
05 Xim 2012

Chem. Commun., 2013,49, 4361-4363

Stereoselective synthesis of aminoindanols via an efficient cascade aza-Michael–aldol reaction

H. Qian, W. Zhao, H. H-Y. Sung, I. D. Williams and J. Sun, Chem. Commun., 2013, 49, 4361 DOI: 10.1039/C2CC37102B

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