Issue 31, 2011

A facile, modular and high yield method to assemble three-dimensional DNA structures

Abstract

We describe a rapid and quantitative method to generate DNA cages of deliberately designed geometry from readily available starting strands. Balancing the incorporation of sequence uniqueness and symmetry in a face-centered approach to 3D construction can result in triangular (TP), rectangular (RP), and pentagonal prisms (PP) without compromising the potential for nanostructure addressability.

Graphical abstract: A facile, modular and high yield method to assemble three-dimensional DNA structures

Supplementary files

Article information

Article type
Communication
Submitted
26 Cig 2011
Accepted
24 Cax 2011
First published
11 Qad 2011

Chem. Commun., 2011,47, 8925-8927

A facile, modular and high yield method to assemble three-dimensional DNA structures

C. K. McLaughlin, G. D. Hamblin, F. A. Aldaye, H. Yang and H. F. Sleiman, Chem. Commun., 2011, 47, 8925 DOI: 10.1039/C1CC11726B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements