Issue 30, 2023

Imidazole–carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging

Abstract

A heavy-atom-free photosensitizer (CI) based on an imidazole–carbazole conjugate exhibited strong fluorescence emission and ROS generation via both type I and II mechanisms. In particular, CI showed efficient photodynamic therapy and fluorescence bioimaging under two-photon (TP) excitation (740 nm) toward HeLa cells with negligible dark toxicity.

Graphical abstract: Imidazole–carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging

Supplementary files

Article information

Article type
Communication
Submitted
08 Qun 2023
Accepted
20 Cig 2023
First published
20 Cig 2023

Chem. Commun., 2023,59, 4503-4506

Imidazole–carbazole conjugate for two-photon-excited photodynamic therapy and fluorescence bioimaging

T. C. Pham, D. J. Lee, D. H. Kim, J. Yoon, T. D. Lam, H. M. Kim and S. Lee, Chem. Commun., 2023, 59, 4503 DOI: 10.1039/D3CC00108C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements