Issue 26, 2023
From the journal:

Chemical Communications

A hypoxia-activated photothermal agent inhibits multiple heat shock proteins for low-temperature photothermal therapy†

Xinhao Zhang,a   Shan-Shan Xue, ORCID logo a   Wei Pan, ORCID logo *a   Kaiye Wang,a   Na Li ORCID logo *a  and  Bo Tang ORCID logo *a  

* Corresponding authors

a College of Chemistry, Chemical Engineering and Materials Science, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Institute of Molecular and Nano Science, Shandong Normal University, Jinan 250014, P. R. China
E-mail: panwei@sdnu.edu.cn, lina@sdnu.edu.cn, tangb@sdnu.edu.cn

Abstract

A near-infrared (NIR) organic photothermal agent (PTA) to inhibit three types of heat shock proteins (HSPs) was synthesized, which could be activated under hypoxic conditions for low-temperature photothermal therapy (PTT) of cancer.

Graphical abstract: A hypoxia-activated photothermal agent inhibits multiple heat shock proteins for low-temperature photothermal therapy

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Article information

DOI
https://doi.org/10.1039/D2CC06598C
Article type
Communication
Submitted
04 Kax 2022
Accepted
07 Cig 2023
First published
14 Cig 2023

Chem. Commun., 2023,59, 3898-3901

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A hypoxia-activated photothermal agent inhibits multiple heat shock proteins for low-temperature photothermal therapy

X. Zhang, S. Xue, W. Pan, K. Wang, N. Li and B. Tang, Chem. Commun., 2023, 59, 3898 DOI: 10.1039/D2CC06598C

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