Issue 88, 2019

Sensing of citrulline modifications in histone peptides by deep cavitand hosts

Abstract

Arrayed cavitand:fluorophore sensor complexes can selectively sense small citrulline modifications at arginine residues on post-translationally modified peptides. The sensor can differentiate between different numbers of citrulline modifications, and a simple two-fluorophore, 6-component array can effect cross-reactive discrimination between single modifications in aqueous solution.

Graphical abstract: Sensing of citrulline modifications in histone peptides by deep cavitand hosts

Supplementary files

Article information

Article type
Communication
Submitted
07 Way 2019
Accepted
11 Dit 2019
First published
11 Dit 2019

Chem. Commun., 2019,55, 13259-13262

Author version available

Sensing of citrulline modifications in histone peptides by deep cavitand hosts

A. D. Gill, B. L. Hickey, S. Wang, M. Xue, W. Zhong and R. J. Hooley, Chem. Commun., 2019, 55, 13259 DOI: 10.1039/C9CC07002H

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