Issue 3, 2014

Nucleobase peptide amphiphiles

Abstract

A new class of peptide materials is introduced, integrating orthogonal aspects of peptide, nucleoside, and amphiphile chemistry. In solution, species such as rod-like or helical micelles are formed, which can lead to nanoribbons under lateral or longitudinal hierarchical growth regimes. Gelation of a wide range of solvents can be induced, including water and aqueous buffer, providing new avenues for nucleobase-specific electrophoresis, oligonucleotide delivery and bioactive cell growth media.

Graphical abstract: Nucleobase peptide amphiphiles

Supplementary files

Article information

Article type
Communication
Submitted
29 Xim 2013
Accepted
17 Qun 2014
First published
17 Qun 2014

Mater. Horiz., 2014,1, 348-354

Nucleobase peptide amphiphiles

C. J. Serpell, M. Barłóg, K. Basu, J. F. Fakhoury, H. S. Bazzi and H. F. Sleiman, Mater. Horiz., 2014, 1, 348 DOI: 10.1039/C3MH00154G

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