Issue 39, 2013

A gold(iii) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

Abstract

A cytotoxic gold(III) complex of meso-tetraphenylporphyrin ([Au(TPP)]Cl, denoted gold-1a) blocks the self-renewal ability of cancer stem-like cells and shows appealing safety pharmacological profiles in rodents.

Graphical abstract: A gold(iii) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

Supplementary files

Article information

Article type
Communication
Submitted
09 Dit 2012
Accepted
15 Xim 2012
First published
16 Xim 2012

Chem. Commun., 2013,49, 4364-4366

A gold(III) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells

C. T. Lum, A. S. Wong, M. C. Lin, C. Che and R. W. Sun, Chem. Commun., 2013, 49, 4364 DOI: 10.1039/C2CC37366A

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