Issue 39, 2013

The tandem intermolecular hydroalkoxylation/claisen rearrangement

Abstract

The Au(I)-catalyzed intermolecular hydroalkoxylation of alkynes with allylic alcohols to provide allyl vinyl ethers that subsequently undergo Claisen rearrangement is reported. This new cascade reaction strategy facilitates the direct formation of γ,δ-unsaturated ketones from simple starting materials in a single step.

Graphical abstract: The tandem intermolecular hydroalkoxylation/claisen rearrangement

Supplementary files

Article information

Article type
Communication
Submitted
01 Dit 2012
Accepted
05 Xim 2012
First published
06 Xim 2012

Chem. Commun., 2013,49, 4157-4159

The tandem intermolecular hydroalkoxylation/claisen rearrangement

J. M. Ketcham, B. Biannic and A. Aponick, Chem. Commun., 2013, 49, 4157 DOI: 10.1039/C2CC37166A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements