Issue 56, 2020

Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

Abstract

A series of near-infrared and photostable Si-oxazine fluorescent dyes was synthesized using a simple three-step procedure, and one of their reduced products, i.e. hydro-Si-oxazine HSiO3, has been utilized to sensitively detect hypochlorous acid and peroxynitrite generation by phagocytes in inflamed and pulmonary fibrosis diseased mice with emission wavelength beyond 750 nm.

Graphical abstract: Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

Supplementary files

Article information

Article type
Communication
Submitted
27 Agd 2020
Accepted
05 Qas 2020
First published
06 Qas 2020

Chem. Commun., 2020,56, 7718-7721

Fluorescence imaging of hypochlorous acid and peroxynitrite in vitro and in vivo with emission wavelength beyond 750 nm

L. Wang, J. Liu, S. Zhao, H. Zhang, Y. Sun, A. Wei and W. Guo, Chem. Commun., 2020, 56, 7718 DOI: 10.1039/D0CC02322A

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