Mio Takagi, Ayako Watanabe, Shigeo Murata and Ryo Takita
Org. Biomol. Chem., 2019,17, 1791-1795
DOI:
10.1039/C8OB02708K,
Communication
A simple protocol for copper-catalyzed arene amination using aqueous ammonia without any additional ligands and organic coordinating solvents has been developed. The reaction pathway via a Cu(I)/Cu(III) mechanism is proposed based on the results of control experiments as well as DFT calculations.
