Issue 2, 2019

Printed nanofilms mechanically conforming to living bodies

Abstract

It is anticipated that flexible wearable/implantable devices for biomedical applications will be established for the development of medical diagnostics and therapeutics. However, these devices need to be compatible with the physical and mechanical properties of the living body. In this minireview, we introduce free-standing polymer ultra-thin films (referred to as “polymer nanosheets”), for which a variety of polymers can be selected as building blocks (e.g., biodegradable polymers, conductive polymers, and elastomers), as a platform for flexible biomedical devices that are mechanically compatible with the living body, and then we demonstrate the use of “printed nanofilms” by combining nanosheets and printing technologies with a variety of inks represented by drugs, conductive nanomaterials, chemical dyes, bio-mimetic polymers, and cells. Owing to the low flexural rigidity (<10−2 nN m) of the polymer nanosheets, which is within the range of living brain slices (per unit width), the flexible printed nanofilms realize bio-integrated structure and display various functions with unique inks that continually monitor or detect biological activities, such as performing surface electromyography, measuring epidermal strain, imaging tissue temperature, organizing cells, and treating lesions in wounds and tumors.

Graphical abstract: Printed nanofilms mechanically conforming to living bodies

Article information

Article type
Minireview
Submitted
13 Dit 2018
Accepted
20 Kax 2018
First published
03 Qun 2019

Biomater. Sci., 2019,7, 520-531

Author version available

Printed nanofilms mechanically conforming to living bodies

K. Yamagishi, S. Takeoka and T. Fujie, Biomater. Sci., 2019, 7, 520 DOI: 10.1039/C8BM01290C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements