Issue 11, 2018

Lighting-up protein–ligand interactions with fluorescent PET (photoinduced electron transfer) sensor designs

Abstract

The fluorescence of sensors 1 and 6, which are designed in terms of photoinduced electron transfer (PET), is switched ‘on’ by factors of 15 and 6 with avidin in a rather selective manner. Sensors 3 and 7, simpler derivatives of 1, are switched ‘on’ by factors of 16 and 7.5 with bovine serum albumin, though at 30-fold higher concentrations.

Graphical abstract: Lighting-up protein–ligand interactions with fluorescent PET (photoinduced electron transfer) sensor designs

Supplementary files

Article information

Article type
Communication
Submitted
29 Qad 2017
Accepted
23 Xim 2017
First published
27 Xim 2017

Chem. Commun., 2018,54, 1319-1322

Lighting-up protein–ligand interactions with fluorescent PET (photoinduced electron transfer) sensor designs

B. McLaughlin, E. M. Surender, G. D. Wright, B. Daly and A. P. de Silva, Chem. Commun., 2018, 54, 1319 DOI: 10.1039/C7CC05929A

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