Issue 17, 2017

Ecocatalyzed Suzuki cross coupling of heteroaryl compounds

Abstract

A bio-based EcoPd was developed for the Suzuki cross coupling of heteroaryl compounds. Based on the ability of Eichhornia crassipes to bioconcentrate Pd in its roots, we addressed the transformation of plant-derived Pd metals to green catalysts. The methodology is based on eco-friendly procedures. It allowed the preparation of a wide range of heterocyclic biaryl and heterocyclic–heterocyclic biaryl compounds, with a low Pd catalyst loading. EcoPd was found to have the ideal microstructure to promote complex Suzuki reactions without ligands or additives. For the first time, post-reaction solution was treated by rhizofiltration. The resulting EcoPd has been reused with the same performance. This work has established the ecocatalysis concept as a powerful strategy for Pd sustainability, with the development of homogeneous catalysts that are easily recycled and reused.

Graphical abstract: Ecocatalyzed Suzuki cross coupling of heteroaryl compounds

Supplementary files

Article information

Article type
Paper
Submitted
07 Qas 2017
Accepted
10 Qad 2017
First published
10 Qad 2017

Green Chem., 2017,19, 4093-4103

Ecocatalyzed Suzuki cross coupling of heteroaryl compounds

G. Clavé, F. Pelissier, S. Campidelli and C. Grison, Green Chem., 2017, 19, 4093 DOI: 10.1039/C7GC01672G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements