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Abstract | Cited by

A naphthalimide based fluorescent sensor displaying a significant increase in emission upon binding CB[7] with notable pH stability was developed and utilized in a surface-bound displacement assay for the rapid detection of CB[7] encapsulation of therapeutically relevant drug classes. Previously unknown binders with moderate to strong affinities were discovered.

Graphical abstract: A naphthalimide derived fluorescent sensor for solid-phase screening of cucurbit[7]uril–guest interactions

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