Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation

Chengcheng Zhou; Yimei Li; Yihui Shen; Ze Lv; Jianguo Feng; Meijuan Jiang; Jian Du; Weijiang Guan

doi:10.1039/D4CC02264E

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Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation†

Chengcheng Zhou,

*^a Yimei Li,^a Yihui Shen,^a Ze Lv,^b Jianguo Feng,

^b Meijuan Jiang,

^c Jian Du^d and Weijiang Guan

*^e

Author affiliations

* Corresponding authors

^a School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China
E-mail: zhoucc@yzu.edu.cn

^b College of Plant Protection, Yangzhou University, Yangzhou 225009, China

^c Department of Chemistry, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China

^d Department of Urology, The First Affiliated Hospital of Shandong First Medical University, No. 16766, Jingshi Road, Jinan 250000, China

^e State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China
E-mail: wjguan@mail.buct.edu.cn

Abstract

Self-oxidative degradation photosensitizers capable of bacterial agglutination and membrane insertion were fabricated based on a simple co-assembly strategy, for efficiently killing P. aeruginosa and rapidly deactivating their function post-treatment.

This article is part of the themed collection: 2024 Emerging Investigators

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DOI: https://doi.org/10.1039/D4CC02264E
Article type: Communication
Submitted: 09 May 2024
Accepted: 07 Jun 2024
First published: 10 Jun 2024

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Chem. Commun., 2024, Advance Article

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Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation

C. Zhou, Y. Li, Y. Shen, Z. Lv, J. Feng, M. Jiang, J. Du and W. Guan, Chem. Commun., 2024, Advance Article , DOI: 10.1039/D4CC02264E

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Chemical Communications

Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation†

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Self-degradable photosensitizer exhibiting bacterial agglutination and membrane insertion toward safe photodynamic ablation

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