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Issue 9, 2016
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Membrane activity of a supramolecular peptide-based chemotherapeutic enhancer

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Abstract

Self-assembly of de novo designed multidomain peptides (MDPs) resulted in functional membrane-active supramolecular nanofibers. The membrane activity was analyzed through fluorescence membrane localization and patch-clamp electrophysiology yielding important information that can be used for the development of a new type of supramolecular peptide-based chemotherapeutic enhancer.

Graphical abstract: Membrane activity of a supramolecular peptide-based chemotherapeutic enhancer

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Supplementary files

Article information


Submitted
10 May 2016
Accepted
29 Jun 2016
First published
30 Jun 2016

Mol. BioSyst., 2016,12, 2695-2699
Article type
Communication

Membrane activity of a supramolecular peptide-based chemotherapeutic enhancer

D. Xu, L. Jiang, L. DeRidder, B. Elmore, M. Bukhari, Q. Wei, D. S. K. Samways and H. Dong, Mol. BioSyst., 2016, 12, 2695
DOI: 10.1039/C6MB00369A

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