Issue 52, 2023

Mitochondria-targeted fluorophores for in vivo NIR-II imaging-guided PDT/PTT

Abstract

A simple yet powerful D–A type-based NIR-II fluorophore (MTF) with mitochondria targeting was constructed. This mitochondrial targeting dye MTF exhibited not only a photothermal effect but also photodynamic performance, and was further fabricated with DSPE-mPEG to generate nanodots for in vivo experiments, achieving strong NIR-II fluorescence tracing of tumors and impressive NIR-II image-guided photodynamic therapy (PDT) and photothermal therapy (PTT).

Graphical abstract: Mitochondria-targeted fluorophores for in vivo NIR-II imaging-guided PDT/PTT

Supplementary files

Article information

Article type
Communication
Submitted
16 May 2023
Accepted
05 Jun 2023
First published
06 Jun 2023

Chem. Commun., 2023,59, 8127-8130

Mitochondria-targeted fluorophores for in vivo NIR-II imaging-guided PDT/PTT

Q. Ding, L. Mei, Y. Liu, S. Zhou, L. Chen, Y. Liang, M. Li, H. Zhou, C. Yin and J. S. Kim, Chem. Commun., 2023, 59, 8127 DOI: 10.1039/D3CC02380J

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements