Issue 10, 2023

An entropy-driven DNA nanomachine for microRNA detection using a personal glucose meter

Abstract

Herein, we developed a reliable and portable biosensor (TDR-PGM nanomachine) for the sensitive detection of microRNA by integrating an efficient toehold-mediated strand displacement reaction module (TDR) and a personal glucose meter (PGM). The system provides a versatile methodology for microRNA detection in real samples and holds broad prospects in point-of-care diagnosis.

Graphical abstract: An entropy-driven DNA nanomachine for microRNA detection using a personal glucose meter

Supplementary files

Article information

Article type
Communication
Submitted
29 Nov 2022
Accepted
05 Jan 2023
First published
06 Jan 2023

Chem. Commun., 2023,59, 1345-1348

An entropy-driven DNA nanomachine for microRNA detection using a personal glucose meter

Q. Wang, Y. He, S. He, S. Yu, Y. Jiang and F. Wang, Chem. Commun., 2023, 59, 1345 DOI: 10.1039/D2CC06479K

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