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Issue 19, 2013
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Clear castable polyurethane elastomer for fabrication of microfluidic devices

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Abstract

Polydimethylsiloxane (PDMS) has numerous desirable properties for fabricating microfluidic devices, including optical transparency, flexibility, biocompatibility, and fabrication by casting; however, partitioning of small hydrophobic molecules into the bulk of PDMS hinders industrial acceptance of PDMS microfluidic devices for chemical processing and drug development applications. Here we describe an attractive alternative material that is similar to PDMS in terms of optical transparency, flexibility and castability, but that is also resistant to absorption of small hydrophobic molecules.

Graphical abstract: Clear castable polyurethane elastomer for fabrication of microfluidic devices

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Article information


Submitted
06 May 2013
Accepted
24 Jul 2013
First published
19 Aug 2013

Lab Chip, 2013,13, 3956-3964
Article type
Paper

Clear castable polyurethane elastomer for fabrication of microfluidic devices

K. Domansky, D. C. Leslie, J. McKinney, J. P. Fraser, J. D. Sliz, T. Hamkins-Indik, G. A. Hamilton, A. Bahinski and D. E. Ingber, Lab Chip, 2013, 13, 3956
DOI: 10.1039/C3LC50558H

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