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Anticancer drug impact on DNA – a study by neutron spectroscopy coupled with synchrotron-based FTIR and EXAFS


Ana L. M. Batista de Carvalho, Adriana P. Mamede, Asha Dopplapudi, Victoria Garcia Sakai, James Doherty, Mark Frogley, Gianfelice Cinque, Peter Gardner, Diego Gianolio, Luís A. E. Batista de Carvalho and M. Paula M. Marques
Phys. Chem. Chem. Phys., 2019,21, 4162-4175
From themed collection: 2019 PCCP HOT Articles

Abstract

Complementary information on drug–DNA interplay has been achieved for Pt/Pd anticancer agents, by a combined QENS, SR-FTIR-ATR and EXAFS approach.


Cell viability and hydration assay based on metamaterial-enhanced terahertz spectroscopy


Yu Liu, Mingjie Tang, Liangping Xia, Wenjing Yu, Jia Peng, Yang Zhang, Marc Lamy de la Chapelle, Ke Yang, Hong-Liang Cui and Weiling Fu
RSC Adv., 2017,7, 53963-53969

Abstract

We analyze cell viability and hydration state of tumor cells in a label-free manner based on metamaterial-enhanced terahertz spectroscopy.


Effect of macromolecular crowding on the kinetics of glycolytic enzymes and the behaviour of glycolysis in yeast


Henrik S. Thoke, Luis A. Bagatolli and Lars F. Olsen
Integr. Biol., 2018,10, 587-597

Abstract

The kinetics of enzymes in crowded environments are described better by the Association Induction hypothesis compared to traditional steady-state kinetics.


Nanostructuration of ionic liquids: impact on the cation mobility. A multi-scale study


Filippo Ferdeghini, Quentin Berrod, Jean-Marc Zanotti, Patrick Judeinstein, Victoria García Sakai, Orsolya Czakkel, Peter Fouquet and Doru Constantin
Nanoscale, 2017,9, 1901-1908

Abstract

The propensity of ionic liquids to self-assemble in transient nanoscopic domains results in scale dependent long-range transport properties.


Visualization of the in situ distribution of contents and hydrogen bonding states of cellular level water in apple tissues by confocal Raman microscopy


Dongmei Li, Zhiwei Zhu and Da-Wen Sun
Analyst, 2020,145, 897-907

Abstract

Raman spectroscopy has been employed for studying the hydrogen bonding states of water molecules for decades, however, Raman imaging data contain thousands of spectra, making it challenging to obtain information on water with different hydrogen bonds.


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