Clinically approved liposomal nanomedicines: lessons learned from the biomolecular corona

Giulio Caracciolo

Nanoscale, 2018, 10, 4167
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The role of surface chemistry in serum protein corona-mediated cellular delivery and gene silencing with lipid nanoparticles

Dongyu Chen, Shanthi Ganesh, Weimin Wang and Mansoor Amiji

Nanoscale, 2019, 11, 8760
DOI: 10.1039/C8NR09855G

EGFR-targeting PLGA-PEG nanoparticles as a curcumin delivery system for breast cancer therapy

Hua Jin, Jiang Pi, Yue Zhao, Jinhuan Jiang, Ting Li, Xueyi Zeng, Peihui Yang, Colin E. Evans and Jiye Cai

Nanoscale, 2017, 9, 16365
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Protein denaturation caused by heat inactivation detrimentally affects biomolecular corona formation and cellular uptake

Johanna Simon, Julius Müller, Artur Ghazaryan, Svenja Morsbach, Volker Mailänder and Katharina Landfester

Nanoscale, 2018, 10, 21096
DOI: 10.1039/C8NR07424K

Improved vaccine-induced immune responses via a ROS-triggered nanoparticle-based antigen delivery system

Xiaoyu Liang, Jianwei Duan, Xuanling Li, Xiaowei Zhu, Youlu Chen, Xiaoli Wang, Hongfan Sun, Deling Kong, Chen Li and Jing Yang

Nanoscale, 2018, 10, 9489
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Theranostic micelles based on upconversion nanoparticles for dual-modality imaging and photodynamic therapy in hepatocellular carcinoma

Yong Han, Yanli An, Gang Jia, Xihui Wang, Chen He, Yinan Ding and Qiusha Tang

Nanoscale, 2018, 10, 6511
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The role of apolipoprotein- and vitronectin-enriched protein corona on lipid nanoparticles for in vivo targeted delivery and transfection of oligonucleotides in murine tumor models

Dongyu Chen, Neha Parayath, Shanthi Ganesh, Weimin Wang and Mansoor Amiji

Nanoscale, 2019, 11, 18806
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Protein Corona Fingerprints of Liposomes: New Opportunities for Targeted Drug Delivery and Early Detection in Pancreatic Cancer

Sara Palchetti, Damiano Caputo, Luca Digiacomo, Anna Capriotti, Roberto Coppola, Daniela Pozzi and Giulio Caracciolo

Pharmaceutics, 2019, 11, 31
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Designing Paper-Based Immunoassays for Biomedical Applications

Delyan Hristov, Cristina Rodriguez-Quijada, Jose Gomez-Marquez and Kimberly Hamad-Schifferli

Sensors, 2019, 19, 554
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Hybrid Nanogels: Stealth and Biocompatible Structures for Drug Delivery Applications

Parisa Eslami, Filippo Rossi and Stefano Fedeli

Pharmaceutics, 2019, 11, 71
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Synthesis, characterization and evaluation of retinoic acid-polyethylene glycol nanoassembly as efficient drug delivery system

Prachi Nagar, Preeti Goyal, Alka Gupta, Ashwani Kumar Sharma and Pradeep Kumar

Nano-Structures & Nano-Objects, 2018, 14, 110
DOI: 10.1016/j.nanoso.2018.01.016

Effect of Glucose on Liposome-Plasma Protein Interactions: Relevance for the Physiological Response of Clinically Approved Liposomal Formulations

Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Aldo Laganà, Roberto Coppola, Damiano Caputo, Mohammad Sharifzadeh, Morteza Mahmoudi and Giulio Caracciolo

Adv. Biosys., 2019, 3, 1800221
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Formation of a protein corona influences the biological identity of nanomaterials

Daniel Nierenberg, Annette R. Khaled and Orielyz Flores

Reports of Practical Oncology & Radiotherapy, 2018, 23, 300
DOI: 10.1016/j.rpor.2018.05.005

Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes In Vivo

Fengling Wang, Yifan Wu, Jiwen Zhang, Huihui Wang, Xiaoting Xie, Xi Ye, Daiyin Peng and Weidong Chen

Drug Metab Dispos, 2019, 47, 364
DOI: 10.1124/dmd.118.085340

Improving the accuracy of pancreatic cancer clinical staging by exploitation of nanoparticle-blood interactions: A pilot study

D. Caputo, M. Cartillone, C. Cascone, D. Pozzi, L. Digiacomo, S. Palchetti, G. Caracciolo and R. Coppola

Pancreatology, 2018, 18, 661
DOI: 10.1016/j.pan.2018.06.002

Principal component analysis of personalized biomolecular corona data for early disease detection

Massimiliano Papi and Giulio Caracciolo

Nano Today, 2018, 21, 14
DOI: 10.1016/j.nantod.2018.03.001

Protein Corona in Response to Flow: Effect on Protein Concentration and Structure

Dhanya T. Jayaram, Samantha M. Pustulka, Robert G. Mannino, Wilbur A. Lam and Christine K. Payne

Biophysical Journal, 2018, 115, 209
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Liposome protein corona characterization as a new approach in nanomedicine

Anna Laura Capriotti, Chiara Cavaliere and Susy Piovesana

Anal Bioanal Chem, 2019, 411, 4313
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Biocorona‐induced modifications in engineered nanomaterial–cellular interactions impacting biomedical applications

Lisa Kobos and Jonathan Shannahan

WIREs Nanomed Nanobiotechnol, 2020, 12
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Biological recognition of graphene nanoflakes

V. Castagnola, W. Zhao, L. Boselli, M. C. Lo Giudice, F. Meder, E. Polo, K. R. Paton, C. Backes, J. N. Coleman and K. A. Dawson

Nat Commun, 2018, 9
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Polymer Therapeutics: Biomarkers and New Approaches for Personalized Cancer Treatment

Stuart Atkinson, Zoraida Andreu and María Vicent

JPM, 2018, 8, 6
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Impact of the protein corona on nanomaterial immune response and targeting ability

Luca Digiacomo, Daniela Pozzi, Sara Palchetti, Alessandra Zingoni and Giulio Caracciolo

WIREs Nanomed Nanobiotechnol, 2020, 12
DOI: 10.1002/wnan.1615

Synthesis, Self-Association, and Solubilizing Ability of an Amphiphilic Derivative of Poly(ethylene glycol) Methyl Ether

T. N. Pashirova, E. A. Burilova, S. S. Lukashenko, O. A. Lenina, V. V. Zobov, A. R. Khamatgalimov, V. I. Kovalenko, L. Ya. Zakharova and O. G. Sinyashin

Russ J Gen Chem, 2017, 87, 2832
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Brain Targeting by Liposome–Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells

Antonietta Arcella, Sara Palchetti, Luca Digiacomo, Daniela Pozzi, Anna Laura Capriotti, Luigi Frati, Maria Antonietta Oliva, Georgia Tsaouli, Rossella Rota, Isabella Screpanti, Morteza Mahmoudi and Giulio Caracciolo

ACS Chem. Neurosci., 2018, 9, 3166
DOI: 10.1021/acschemneuro.8b00339

Overcoming Hurdles in Nanoparticle Clinical Translation: The Influence of Experimental Design and Surface Modification

Shreffler, Pullan, Dailey, Mallik and Brooks

IJMS, 2019, 20, 6056
DOI: 10.3390/ijms20236056

Exploitation of nanoparticle-protein interactions for early disease detection

Massimiliano Papi, Valentina Palmieri, Sara Palchetti, Daniela Pozzi, Luca Digiacomo, Elia Guadagno, Marialaura del Basso De Caro, Marina Di Domenico, Serena Ricci, Roberto Pani, Morteza Mahmoudi, Angelina Di Carlo and Giulio Caracciolo

Appl. Phys. Lett., 2019, 114, 163702
DOI: 10.1063/1.5098081

Engineered Polymeric Materials for Biological Applications: Overcoming Challenges of the Bio–Nano Interface

Simpson, Smith, Thurecht and Such

Polymers, 2019, 11, 1441
DOI: 10.3390/polym11091441

A rapid and efficient technique for liposomal and nonliposomal drug pharmacokinetics studies using magnetic nanoprobes and its application to leakage kinetics of liposomes

Yunna Chen, Lei Wang, Dongdong Guo, Chenming Sheng, Haozhi Dai, Xiaoyan Shi, Wenjing Zhang, Qianqian Huang, Can Peng and Weidong Chen

Journal of Chromatography A, 2018, 1580, 2
DOI: 10.1016/j.chroma.2018.10.038

The hard protein corona of stealth liposomes is sparse

Kasper Kristensen, Trine B. Engel, Allan Stensballe, Jens B. Simonsen and Thomas L. Andresen

Journal of Controlled Release, 2019, 307, 1
DOI: 10.1016/j.jconrel.2019.05.042

Human Biomolecular Corona of Liposomal Doxorubicin: The Overlooked Factor in Anticancer Drug Delivery

Giulio Caracciolo, Sara Palchetti, Luca Digiacomo, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Heinz Amenitsch, Paolo Maria Tentori, Valentina Palmieri, Massimiliano Papi, Francesco Cardarelli, Daniela Pozzi and Aldo Laganà

ACS Appl. Mater. Interfaces, 2018, 10, 22951
DOI: 10.1021/acsami.8b04962

A health concern regarding the protein corona, aggregation and disaggregation

Mojtaba Falahati, Farnoosh Attar, Majid Sharifi, Thomas Haertlé, Jean-François Berret, Rizwan Hasan Khan and Ali Akbar Saboury

Biochimica et Biophysica Acta (BBA) - General Subjects, 2019, 1863, 971
DOI: 10.1016/j.bbagen.2019.02.012

Nanoformulation properties, characterization, and behavior in complex biological matrices: Challenges and opportunities for brain-targeted drug delivery applications and enhanced translational potential

Vibhuti Agrahari, Pierre-Alain Burnouf, Thierry Burnouf and Vivek Agrahari

Advanced Drug Delivery Reviews, 2019, 148, 146
DOI: 10.1016/j.addr.2019.02.008