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Issue 16, 2020
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Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications

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Abstract

Fast, high-resolution, non-destructive and quantitative characterization methods are needed to develop materials with tailored properties at the nanoscale or to understand the relationship between mechanical properties and cell physiology. This review introduces the state-of-the-art force microscope-based methods to map at high-spatial resolution the elastic and viscoelastic properties of soft materials. The experimental methods are explained in terms of the theories that enable the transformation of observables into material properties. Several applications in materials science, molecular biology and mechanobiology illustrate the scope, impact and potential of nanomechanical mapping methods.

Graphical abstract: Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications

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Article information


Submitted
02 Apr 2020
First published
14 Jul 2020

This article is Open Access

Chem. Soc. Rev., 2020,49, 5850-5884
Article type
Review Article

Nanomechanical mapping of soft materials with the atomic force microscope: methods, theory and applications

R. Garcia, Chem. Soc. Rev., 2020, 49, 5850
DOI: 10.1039/D0CS00318B

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    [Original citation] - Published by The Royal Society of Chemistry.

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