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Issue 18, 2014
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Synthetic micro/nanomotors in drug delivery

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Abstract

Nanomachines offer considerable promise for the treatment of diseases. The ability of man-made nanomotors to rapidly deliver therapeutic payloads to their target destination represents a novel nanomedicine approach. Synthetic nanomotors, based on a multitude of propulsion mechanisms, have been developed over the past decade toward diverse biomedical applications. In this review article, we journey from the use of chemically powered drug-delivery nanovehicles to externally actuated (fuel-free) drug-delivery nanomachine platforms, and conclude with future prospects and challenges for such practical propelling drug-delivery systems. As future micro/nanomachines become more powerful and functional, these tiny devices are expected to perform more demanding biomedical tasks and benefit different drug delivery applications.

Graphical abstract: Synthetic micro/nanomotors in drug delivery

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Article information


Submitted
06 Jun 2014
Accepted
30 Jun 2014
First published
03 Jul 2014

Nanoscale, 2014,6, 10486-10494
Article type
Review Article
Author version available

Synthetic micro/nanomotors in drug delivery

W. Gao and J. Wang, Nanoscale, 2014, 6, 10486
DOI: 10.1039/C4NR03124E

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