Jump to main content
Jump to site search

Issue 98, 2014
Previous Article Next Article

Aptamer-based biosensors for the rapid visual detection of flu viruses

Author affiliations

Abstract

RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron microscopy (TEM). Changes in size and structure of the AuNS coated virus can be used to detect the viruses. We show that sedimentation with a low cost centrifuge and visual determination can detect 3 × 108 viral particles.

Graphical abstract: Aptamer-based biosensors for the rapid visual detection of flu viruses

Back to tab navigation

Supplementary files

Article information


Submitted
06 Oct 2014
Accepted
24 Oct 2014
First published
24 Oct 2014

Chem. Commun., 2014,50, 15533-15536
Article type
Communication
Author version available

Aptamer-based biosensors for the rapid visual detection of flu viruses

T. T. Le, B. Adamiak, D. J. Benton, C. J. Johnson, S. Sharma, R. Fenton, J. W. McCauley, M. Iqbal and A. E. G. Cass, Chem. Commun., 2014, 50, 15533
DOI: 10.1039/C4CC07888H

Social activity

Search articles by author

Spotlight

Advertisements