Issue 25, 2017
From the journal:

RSC Advances

Novel triterpenoid derivatives from Eucomis bicolor Bak. (Hyacinthaceae: Hyacinthoideae)†

Jaspreet K. Sihra,a   Moses K. Langat,ab   Neil R. Crouch,bc   Jean-Marc Nuzillard,d   Bertrand Plainchontd  and  Dulcie A. Mulholland ORCID logo *ab  

* Corresponding authors

a Department of Chemistry, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey, UK
E-mail: d.mulholland@surrey.ac.uk
Tel: +44 (0)1483686751

b School of Chemistry and Physics, University of KwaZulu-Natal, Durban, South Africa

c Biodiversity Economy Unit, South African National Biodiversity Institute, PO Box 52099, Berea Road 4007, Durban, South Africa

d Université de Reims Champagne-Ardenne, Institut de Chimie Moléculaire de Reims, CNRS UMR 7312, SFR CAP-Santé, BP 1039, 51687 Reims Cedex 02, France

Abstract

The bulbs of Eucomis bicolor (Hyacinthoideae) yielded fourteen novel natural compounds, including (17S)-3-oxo-24,25,26,27,28-pentanorlanost-8-en-23,17α-olide, whose structure was determined using the logic for structure determination program, and nine novel lanosterol glycosides. Compounds were screened against the NCI-59 cancer cell panel but showed limited activity.

Graphical abstract: Novel triterpenoid derivatives from Eucomis bicolor Bak. (Hyacinthaceae: Hyacinthoideae)

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Article information

DOI
https://doi.org/10.1039/C6RA28584H
Article type
Paper
Submitted
22 Dec 2016
Accepted
24 Feb 2017
First published
08 Mar 2017
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2017,7, 15416-15427

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Novel triterpenoid derivatives from Eucomis bicolor Bak. (Hyacinthaceae: Hyacinthoideae)

J. K. Sihra, M. K. Langat, N. R. Crouch, J. Nuzillard, B. Plainchont and D. A. Mulholland, RSC Adv., 2017, 7, 15416 DOI: 10.1039/C6RA28584H

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