RSC - Lab Chip latest articles

Bridging dimensions: Combining one-and two-photon 3D printing for microfluidic device fabrication

Lab Chip, 2026, Accepted Manuscript
DOI: 10.1039/D6LC00261G, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Oliver Walker, Robin R Benedix, Julian Fischer, Kai Hirzel, Cosima Stubenrauch, Michael Heymann
Additive manufacturing has been invaluable for 3D microfluidic integration. We combine high-resolution two-photon printed microfluidic features with fast one-photon printing to reduce overall fabrication time by about 20fold without compromising...
The content of this RSS Feed (c) The Royal Society of Chemistry

A dual-mode vertical flow assay for species-specific identification and total bacteria load assessment from a single urine sample

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00265J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Shu-Yun Sheu, Ching-Fen Shen, Chao-Min Cheng
Rapid urine screening requires simultaneous pathogen identification and clinically relevant bacteria burden assessment, yet most paper-based assays provide only one of these outputs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Centrifugal microfluidics for rapid target analyte quantification in airborne bioaerosol

Lab Chip, 2026, Accepted Manuscript
DOI: 10.1039/D6LC00061D, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Soong Won Cho, Michael Brothers, ZIYU CHEN, Samet Şahin, Yirui Xiong, Nicole Schaeublin, Douglas Adkins, Charles Call, Anthony Banks, Steve S. Kim, John A. Rogers
Bioaerosols comprise an array of airborne particles that can be benign, contain irritants (i.e., allergens), or disseminate pathogens. Current fieldable devices are incapable of discriminating between benign bioaerosols and pathogenic...
The content of this RSS Feed (c) The Royal Society of Chemistry

Acoustofluidic trapping of microparticles to axially centered wires in cylindrical microcapillaries

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00047A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Ruben J. Trujillo, Phung H. Bui, Andrew P. Shreve, Matthew J. Campen, Menake E. Piyasena, Steven W. Graves
Acoustofluidic trapping in cylindrical microcapillaries concentrates microparticles onto an axially centered micro-wire, demonstrating particle trapping to a suspended microstructure in flowing microfluidic systems.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Direct Observation of Anomalous CO2 Dispersion in Multi-scale Porous Media

Lab Chip, 2026, Accepted Manuscript
DOI: 10.1039/D6LC00244G, Paper

Qihui Wu, Yulin Zhang, Yibo Yang, Jun Yao, Yongfei Yang, Hai Sun, Lei Zhang, Junjie Zhong
The CO2 dispersion dynamics in multi-scale porous media is critical for various environmental applications. The heterogeneity of natural porous media lead to the immobile zones and preferential flow paths, resulting...
The content of this RSS Feed (c) The Royal Society of Chemistry

Dynamic biomimicry in skin-on-a-chip: Multi-scale construction to translational dermatology, drug screening and cosmetic evaluation

Lab Chip, 2026, Accepted Manuscript
DOI: 10.1039/D5LC01173F, Critical Review

Linwei Sang, Ajing Liu, Haochen Wang, Wanyi Li, Qin Tu, Jinyi Wang
Skin-on-a-chip has emerged as a promising platform for reconstructing human skin physiology in vitro with enhanced biological relevance. Unlike conventional static models, these systems can better reproduce key dynamic features...
The content of this RSS Feed (c) The Royal Society of Chemistry

Traumatic brain injury-on-a-chip: a microfluidic device for the compression of cortical spheroids

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00058D, Paper

Mauricio Araiza Canizales, Alexander McGhee, Yang Wan, Jing Zhang, Emily Blick, Rafael D. González-Cruz, Diane Hoffman-Kim, Haneesh Kesari, Christian Franck
A three-layer microfluidic platform for in situ compression, staining and monitoring of cortical spheroids to study mild traumatic brain injury.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Mechanoadaptive root growth in Medicago sativa under controlled microhydrodynamic environments

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC00827A, Paper

Doh-Won Yi, Jeongmok Kim, Joong Yull Park
A microfluidic plant-on-a-chip platform reveals a hydrodynamic threshold governing Medicago sativa root and root hair growth, as quantified by CFD simulations.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Large field of view fluorescence imaging of microfluidic devices with a tandem-lens macroscope

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC00959F, Communication

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Daniel A. Mokhtari, Ali Lashkaripour, Polly M. Fordyce
An automated transfluorescence tandem-macro-lens optomechanical system (macroscope) capable of sensitive, multi-channel fluorescence imaging over a very large field of view (34 mm diameter, 740 square mm) and with low-micron resolution.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Correction: Rapid pan-cancer detection via label-free impedance profiling of cell-free DNA

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC90051H, Correction

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Tejal Dube, Puja Prasad, Pragya Swami, Ankita Singh, Meenakshi Verma, Parul Tanwar, Shantanu Chowdhury, Shalini Gupta
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

3D printing monolithic, multifunctional polymer acoustofluidic devices with tunable mixing and particle focusing

Lab Chip, 2026, 26,3381-3391
DOI: 10.1039/D6LC00107F, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Roxanne Kate Balanay, Justin W. Yip, Justin Do, Omair Adil, Keith Johnson, Tyler R. Ray
Acoustic forces offer a powerful, contact-free modality for manipulating particles and fluids within microfluidic lab-on-a-chip systems.
The content of this RSS Feed (c) The Royal Society of Chemistry

Point-of-care SERS platforms: integrating microfluidics and machine learning for disease screening

Lab Chip, 2026, 26,3282-3319
DOI: 10.1039/D6LC00202A, Critical Review

Biqing Chen, Xiaohong Qiu, Yang Li
Microfluidic SERS platforms enable ultrasensitive, high-throughput bioanalysis via Raman enhancement and microfluidic control. Plasmonic integration supports multiplexed biomarker detection for biomedical research and clinical translation.
The content of this RSS Feed (c) The Royal Society of Chemistry

Multiplexed nanophotonic biosensing and deep learning-driven protein quantification for traumatic brain injury diagnosis at the point of care

Lab Chip, 2026, 26,3555-3581
DOI: 10.1039/D5LC01079A, Paper

Jiayu Liu, Yuxin Wang, Shichao Su, Meng Su, Wenying Lv, Zhao Gao, Congwei Liu, Yanteng Li, Junzhao Sun, Peng Wang, Baorui Guo, Fan Yang, Renke He, Yanlin Song, Zeying Zhang, Jianning Zhang, Gang Cheng
This integrated nanophotonic biosensor platform enables multiplex detection of TBI biomarkers through an end-to-end process, offering a rapid, ultrasensitive, and field-deployable solution for acute brain injury diagnostics.
The content of this RSS Feed (c) The Royal Society of Chemistry

A portable modular acoustic streaming vortex platform for flexible and robust fabrication of monodisperse micromaterials

Lab Chip, 2026, 26,3546-3554
DOI: 10.1039/D6LC00054A, Paper

Xiaoping Miao, Tianao Chen, Jijie Fu, Shilu Zhu, Mei Lan, Huayi Fu, Zhiqiang Zhu, Mingzhai Sun, Ronald X. Xu
A modular acoustic streaming vortex (MASV) platform has been developed for off-chip production of monodisperse microdroplets with broad size tunability and versatile viscoelastic properties.
The content of this RSS Feed (c) The Royal Society of Chemistry

Thin stencil membrane-assisted high throughput single-cell to cluster of cells micropatterning and large-size biomolecular transfection in primary and stem cells

Lab Chip, 2026, 26,3508-3527
DOI: 10.1039/D6LC00164E, Paper

Donia Dominic, Srabani Kar, Rajdeep Ojha, Moeto Nagai, Tuhin Subhra Santra
Schematic illustration of high-throughput biomolecular delivery in single-cell patterns. Pulsed laser scanning-activated photoporation mediated through a micropatterned rGO device facilitates intracellular delivery in cell micropatterns.
The content of this RSS Feed (c) The Royal Society of Chemistry

Lab-on-a-chip systems for microplastic and nanoplastic sampling, detection, characterization and bioassessment

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00116E, Critical Review

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Liyuan Gong, Erfan Eskandari, Md Iftakhar Khan, Yang Lin
Integrated lab-on-a-chip systems enable streamlined sampling, detection, characterization, and bioassessment of micro- and nanoplastics, bridging environmental monitoring with human health risk assessment.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Valved microfluidics with Ostemers

Lab Chip, 2026, 26,3473-3484
DOI: 10.1039/D5LC00968E, Paper

Naveen Kumar K. R., Saima Hamid, A. K. Niketa, Ekta Prajapati, Shishir Kumar
Ostemer-based valved microfluidics with NOA 84 as a membrane replace PDMS using a three-layer design enables 200 ms switching time with strong chemical resistance, enabling robust and flexible microfluidic systems.
The content of this RSS Feed (c) The Royal Society of Chemistry

Microfluidic profiling of suspension cell–metal adhesion at single-cell resolution under flow

Lab Chip, 2026, 26,3582-3590
DOI: 10.1039/D5LC01090J, Paper

Eunyoung Park, Seungjin Kang, Jieung Oh, Sangwoo Kim, Ung Hyun Ko
High-throughput quantification of cell–metal adhesion using single-cell transit velocity measurements in a microfluidic channel.
The content of this RSS Feed (c) The Royal Society of Chemistry

An AI-enabled tool for quantifying overlapping red blood cell sickling dynamics in microfluidic assays

Lab Chip, 2026, 26,3366-3380
DOI: 10.1039/D6LC00108D, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Nikhil Kadivar, Guansheng Li, Jianlu Zheng, Ming Dao, George Em Karniadakis, Mengjia Xu
AI-assisted masks train nnU-Net to predict cell masks, followed by optional watershed refinement, labeling, counting, and sickling analysis.
The content of this RSS Feed (c) The Royal Society of Chemistry

Nanomembrane-based microfluidic platform with embedded electrical pressure transducer for on-chip nanoparticle quantification

Lab Chip, 2026, 26,3447-3458
DOI: 10.1039/D6LC00071A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Zachary Morris, Juliana Chawich, Owen Perreault, Simon Chewchuk, Kate Gragg, Vincent Tabard-Cossa, James L. McGrath, Michel Godin
A microfluidic device with an integrated PDMS pressure transducer and a nanoporous membrane to capture nanoparticles. A predictive algorithm then infers particle concentration in solution from the dynamics of pressure change within the microchannels.
The content of this RSS Feed (c) The Royal Society of Chemistry

On cloud microfluidic experiment platform powered by in situ maskless lithography

Lab Chip, 2026, 26,3413-3424
DOI: 10.1039/D6LC00035E, Paper

Ratul Paul, Declan Coster, Yuwen Zhao, Yi Liu, Yaling Liu
Cloud microfluidic platform for remote design, fabrication, and testing via maskless lithography. Integrates microscopy, flow control, and analysis, enabling users to create devices, run experiments, and access data online for research and education.
The content of this RSS Feed (c) The Royal Society of Chemistry

A novel 3D-printed tool for in vitro cell interaction studies under flow conditions

Lab Chip, 2026, 26,3528-3545
DOI: 10.1039/D6LC00033A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Katharina Skoll, Maria Zobl, Elke Heiss, Barbara Braunboeck, Samuel Meerkatz, Franz Radner, Samuel Castonguay, Markus Holzner, Adriana Zbiral, Michael Wirth, Maria Anzengruber
Experimental setup, sedimentation and shear stress influence cell interaction exposing the limits of static in vitro assays. The FlowCube emerges as a versatile, accessible platform that enables in vitro evaluation in a dynamic flow setting.
The content of this RSS Feed (c) The Royal Society of Chemistry

Capillary microsampling enables on-site collection and storage of plant sap

Lab Chip, 2026, 26,3485-3492
DOI: 10.1039/D6LC00201C, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ellinor Hedberg, Jaime Sebastián-Azcona, Federico Ribet, Virginia Hernandez-Santana, Göran Stemme, Antonio Diaz Espejo, Niclas Roxhed
A novel microfluidic plant sap sampling and storage device inspired by the concept of DBS, providing a practical alternative to destructive methods, supporting repeated sampling from the same plant and enabling longitudinal metabolic monitoring.
The content of this RSS Feed (c) The Royal Society of Chemistry

Dynamic gap structure for high-throughput measurement of cellular mechanical properties

Lab Chip, 2026, 26,3435-3446
DOI: 10.1039/D5LC01162K, Paper

Doudou Ma, Nobutoshi Ota, Masaya Taniguchi, Yu-Hau Ye, Yuri Ito, Kazunori Okano, Naomi Tanga, Yoichiroh Hosokawa, Kazuya Sakai, Yo Tanaka, Koki Yamamoto, Yaxiaer Yalikun
Pressure-tunable dynamic gap in an all-glass microfluidic device enables clog-resistant, high-throughput cell mechanotyping via defined compression, quantifying apparent Young's modulus as a robust alternative to flow-based deformability cytometry.
The content of this RSS Feed (c) The Royal Society of Chemistry

Independent parallel production of tunable blood clot analogues in hourglass-profiled circular PDMS fluidic channels

Lab Chip, 2026, 26,3425-3434
DOI: 10.1039/D6LC00190D, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Chun-Hsin Hsu, To-Wen Chen, Wei-Jen Soong, Chihchen Chen
A dual-loop flow system is presented, enabling parallel, independent blood clot analogue production in hourglass-profiled channels, with integrated reagent delivery, real-time imaging, and flow-rate monitoring.
The content of this RSS Feed (c) The Royal Society of Chemistry

Bacterial extracellular vesicles indirectly destabilize a human stem cell-derived blood–brain barrier on-chip through pro-inflammatory stimulation of immune cells

Lab Chip, 2026, 26,3327-3344
DOI: 10.1039/D6LC00067C, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Louis P. Widom, Panteha Torabian, Michelle A. Trempel, Molly C. McCloskey, Lea V. Michel, James L. McGrath, Thomas R. Gaborski
Conditioned medium from macrophages stimulated with Escherichia coli-derived bacterial extracellular vesicles (BEVs) caused disruption of a human blood–brain barrier lab-on-chip, but direct BEV treatment did not cause a similar disruptive effect.
The content of this RSS Feed (c) The Royal Society of Chemistry

Flow-programmable and reversible surface-induced LLPS in nanofluidic channels

Lab Chip, 2026, 26,3493-3507
DOI: 10.1039/D6LC00003G, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Ryoichi Ohta, Zhixin Zhao, Xuan Yan, Ruying Wang, Kazuma Mawatari
Nanofluidic confinement enables instantaneous formation and hydrodynamic peel-off of surface LLPS films. In the future, this reversible 3D phase is expected to accommodate functional molecules beyond static 2D limits.
The content of this RSS Feed (c) The Royal Society of Chemistry

Gut–liver-on-a-chip enables mechanistic study and risk assessment of drug-induced liver injury and drug–drug interactions

Lab Chip, 2026, 26,3345-3365
DOI: 10.1039/D5LC01094B, Paper

Yue Yu, Tian Lin, Xiao Ye, Yupeng Wang, Rongrong Xiao, Baiyang Sun, Manman Zhao, Jie Song, Bo Li, Xiaobing Zhou
A gut–liver-on-chip was established to conduct case studies of the toxicity–exposure relationship, time-dependent hepatotoxicity, enzyme/transporter-mediated drug–drug interaction studies, and first-pass effects.
The content of this RSS Feed (c) The Royal Society of Chemistry

Size-based sorting of cancer cells reveals functional heterogeneity among subpopulations

Lab Chip, 2026, 26,3459-3472
DOI: 10.1039/D5LC01042J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Esra Yilmaz, Zhimeng Fan, Jason P. Beech, Vinay S. Swaminathan, Jonas O. Tegenfeldt
Cancer cells of type MDA-MB-231 were sorted based on size using deterministic lateral displacement. The results reveal differences with respect to size in morphology, adhesion dynamics, and invasion potential.
The content of this RSS Feed (c) The Royal Society of Chemistry

Fluid mechanics of thin blood films to detect anemia and sickle cell disease

Lab Chip, 2026, 26,3401-3412
DOI: 10.1039/D5LC00943J, Paper

Mahrukh A. Mir, Mahesh S. Tirumkudulu, Bhavesh Raicha
We determine the viscosity of blood from the length of blood smears. Viscosity below a threshold indicates anemia, while viscosity increase due to stiffening of red blood cells upon deoxygenation indicates sickle cell disease.
The content of this RSS Feed (c) The Royal Society of Chemistry

Development of a nasal airway-on-chip co-culture model to study particulate matter exposure

Lab Chip, 2026, 26,3392-3400
DOI: 10.1039/D5LC00978B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Amanda C. Walls, Adrienne S. Vaughan, Kartik Balachandran
A nasal airway-on-chip designed for culture of nasal epithelial and endothelial cells in co-culture with the epithelial cells in air–liquid interface culture and exposed to physiological breathing airflows.
The content of this RSS Feed (c) The Royal Society of Chemistry

Polydiacetylene (PDA) coated paper-based fluorescence sensor for the detection and quantification of bisphenol

Lab Chip, 2026, 26,3320-3326
DOI: 10.1039/D5LC00821B, Communication

Gayathri Loganathan, Shubham Gurav, Khaja Moinuddin Shaik, Pirangi Srikanth, Aman Bhardwaj, Sukhendu Nandi
An innovative portable point-of-care device that rapidly and accurately detects and quantifies bisphenol. This sensor ensures quick results, making it an indispensable tool for health and safety monitoring.
The content of this RSS Feed (c) The Royal Society of Chemistry

Adeno-Associated Viral Vector Purification Using a Centrifugal Microfluidic System: Towards Workflow Automation for Low-Volume Sample Processing

Lab Chip, 2026, Accepted Manuscript
DOI: 10.1039/D6LC00382F, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Matthias Geissler, Lidija Malic, Liviu Clime, Dillon Da Fonte, Christina Nassif, Mojra Janta, Caroline Miville-Godin, Daniel Brassard, Nasha Nassoury, Richard Gingras, Nazila Nazemi-Moghaddam, Parminder Chahal, Renald Gilbert, Teodor Veres
This paper describes the development of an integrated assay for the purification of Adeno-associated virus (AAV) particles from crude lysate using a microfluidic cartridge and a centrifugal platform that enables...
The content of this RSS Feed (c) The Royal Society of Chemistry

Deterministic radial displacement: modular, reconfigurable, and reusable

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00348F, Paper

Sean C. McCabe, Shilun Feng, David W. Inglis
By cylindrically revolving a DLD array, devices can be fabricated in segments and simply assembled, delivery modularity and reusability.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Integrated microfluidic biosensors: shaping the future of quantitative life sciences and on-chip molecular diagnostics

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC00957J, Critical Review

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Ty Naquin, Chloe Naquin, Qian Wu, Ying Chen, Aidan Canning, Kaichun Yang, Yuna Li, Shuaiguo Zhao, Yun Ling, Zhiteng Ma, Ke Jin, Ye He, Shujie Yang, Luke P. Lee, Tony Jun Huang
Integrated microfluidic biosensors have rapidly evolved into powerful platforms to meet the increasing demand for ultrasensitive and high-throughput quantitative analysis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Tunable Self-Assembling Cellular Microarray for Single-Neutrophil Vital and Suicidal Extracellular Traps

Lab Chip, 2026, Accepted Manuscript
DOI: 10.1039/D5LC01156F, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Jacob Doon-Ralls, Sophia Mayone, Xilal Y. Rima, Dharti Shantaram, Kim Truc Nguyen, Ajeet Singh, Bradley J. Needleman, Sabrena Noria, Stacy Brethauer, Kyle A. Perry, David Wood, Anahita D. Jalilvand, Willa A. Hsueh, Eduardo Reátegui
Neutrophils, the innate immune system's first line of defense, function in pathogen removal through diverse cellular responses. One critical response is neutrophil extracellular trap (NET) formation, which, despite its importance...
The content of this RSS Feed (c) The Royal Society of Chemistry

Capillary flow-driven paper-based microfluidic sensor for NDMA detection in water

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00165C, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Prakash Aryal, Jade Manna-Rubenstein, Tessa Whitaker, Eric Brack, Charles S. Henry
Detection of N-nitrosodimethylamine (NDMA) via on-chip photonitrosation followed by dual colorimetric detection using two complementary metal complexation systems.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A quantitative rapid test for urine creatinine via Fenton's reaction and a self-driven microfluidic device

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00249H, Paper

Hogi Hartanto, Jiaheng Li, Cheuk Chun Szeto, Ting-Hsuan Chen
A self-driven microfluidic chip converting urine creatinine into a length of a visual bar using creatinine's inhibition to Fenton's reaction, achieving limit of detection of 20.11 mg dL⁻¹ and high compatibility with clinical urine samples.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Modular microfluidic probe for addressable fluidic landscapes

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00133E, Paper

Ayoub Glia, Muhammedin Deliorman, Mohammad A. Qasaimeh
Plug-and-play IPOF microfluidics converts open-space flows into addressable chemical nodes for programmable reagent delivery, gradient discretization, and multiplexed surface patterning.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Auto-SELEX: a fully automated microfluidic platform for rapid discovery of high-affinity aptamers

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00275G, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yang Bu, Yuze Liu, Anni Hu, Yung Ching Lee, Levent Yobas
A fully automated microfluidic SELEX that accelerates weeks-long aptamer discovery to 30 min selection rounds by integrating free-solution electrokinetic partitioning through an artificial sieve with plasmonic bead-based PCR using Au nanorods.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Learning-aided design of micropost arrays for optimizing interface stability and mass transport in organs-on-chips

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC01180A, Paper

Daeho Kim, Suhwan Lee, Suyeon Kim, Yoojeong Noh, Eunseop Yeom, Song Ih Ahn
We use simulation-guided multi-objective optimization of micropost geometry to stabilize hydrogel interfaces while balancing mass transport and interface stability.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

3D stamp-integrated open-top microfluidic organ-on-a-chip for high-fidelity and functional reconstruction of vascularized microtissue models

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00096G, Paper

Chenyang Zhou, Feifan Wang, Jiaqi Xu, Aochen Wang, Hanping Song, Luyao Wei, Guoxiang Fu, Xiaolin Wang
A open-top microfluidic organ-on-a-chip that integrates stamp-based patterning with sequential cellular assembly to achieve simultaneous construction of organ-specific topological architectures and perfusable vascular networks.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Acoustofluidic separation of oblate spheroids from spheres using acoustic radiation torque and force

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00140H, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Muhammad Soban Khan, Mushtaq Ali, Yong Bin Bang, Seong Jae Lee, Jinsoo Park
We propose label-free acoustofluidic separation of oblate spheroids from spheres using traveling surface acoustic wave-induced radiation torque and force, achieving high-purity, high-recovery separation of polymer microparticles and red blood cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A microfluidic dermal fibroblast–macrophage co-culture on a chip linking inflammatory signalling to barrier-associated function

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00175K, Paper

Preeda Larpthavee, Thitikorn Chomthong, Pareesa Pormrungruang, Suvimol Surassmo, Sakon Rahong
Immune-responsive microfluidics integrates dermal fibroblast–macrophage co-culture in 3D collagen to model inflammation. LPS induces NO/TNF-α responses, while nanocarriers suppress inflammation and restore ECM, enabling fast, animal-free drug screening.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

DROP-LCMS for wastewater surveillance of viral disease

Lab Chip, 2026, 26,3013-3019
DOI: 10.1039/D6LC00131A, Communication

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Jiaxi Peng, Vigneshwar Rajesh, Jiarui Shen, Jianxian Sun, Calvin Chan, Yechen Hu, Hui Peng, Aaron R. Wheeler
A new microfluidic technique, DROP-LCMS, is introduced for semi-automated processing of wastewater samples for surveillance of viral disease.
The content of this RSS Feed (c) The Royal Society of Chemistry

Predicting human pharmacokinetic parameters of drugs using a multi-tissue chip platform integrating liver, kidney, and skeletal muscle microphysiological systems

Lab Chip, 2026, 26,3054-3068
DOI: 10.1039/D6LC00008H, Paper

Jason Sherfey, Shiny Amala Priya Rajan, Lauren M. Nichols, Paarth Parekh, J. Tyler Smith, Lauren Gregory, Frances Clark, Eugene P. Kadar, Shivam Ohri, Billy T. George, David Tess, James R. Gosset, Jennifer Liras, Emily Geishecker, R. Scott Obach, Murat Cirit
A combinatorial NAM approach integrating multi-tissue chip with QSP modeling enables accurate prediction of human exposure for hepatically and renally cleared small molecules.
The content of this RSS Feed (c) The Royal Society of Chemistry

A combinatorial screening platform for in situ gene delivery to adherent cells via digital microfluidics and flexible electrodes

Lab Chip, 2026, 26,3256-3269
DOI: 10.1039/D6LC00124F, Paper

Yi Weng, Xiangyu Ren, Fuqiang Guo, Weichao Wu, Bin Wang, Chaobo Li
The PDES platform solves the bottlenecks of traditional electroporation methods: manual operation, high reagent use, and low throughput. The micro-level automated reaction system allows multidimensional orthogonal screening and fast optimization of electrical parameters and biological components.
The content of this RSS Feed (c) The Royal Society of Chemistry

Systematic investigation of double emulsion dewetting dynamics for the robust production of giant unilamellar vesicles

Lab Chip, 2026, 26,3039-3053
DOI: 10.1039/D6LC00098C, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Wenyang Jing, Heewon Noh, Timothy J. C. Tan, Nicholas C. Wu, Hee-Sun Han
Decoding dewetting dynamics in double emulsions establishes predictive rules for robust, tunable GUV assembly. This physics-based framework provides systematic guidance to optimize GUV production across varied lipid, aqueous, and fluidic parameters.
The content of this RSS Feed (c) The Royal Society of Chemistry

Estimating single-cell elastic modulus in a serial microfluidic cytometer from time-of-flight and fluorescence signals analysis

Lab Chip, 2026, 26,3168-3183
DOI: 10.1039/D5LC00930H, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Graylen R. Chickering, Leroy L. Jia, Matthew DiSalvo, Megan A. Catterton, Paul N. Patrone, Eric M. Darling, Gregory A. Cooksey
Particles can migrate in flow based on size and deformability, resulting in measurable time-of-flight differences. These same mechanical properties can reflect changes in cellular state, function, and disease.
The content of this RSS Feed (c) The Royal Society of Chemistry

Centrifuge-free separation of plasma from milliliters of whole blood for point-of-care diagnostics

Lab Chip, 2026, 26,3139-3152
DOI: 10.1039/D6LC00135A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Christia M. Victoriano, Bianca Arraiza Carlo, Abigail G. Ayers, Kelia A. Human, Samuel K. Sia
PlasmaLIFT enables automated plasma separation from milliliters of whole blood by integrating immunomagnetic red blood cell depletion with dual-membrane filtration.
The content of this RSS Feed (c) The Royal Society of Chemistry

Stretchable mesoporous electrodes as a versatile platform for minimally invasive surgical devices

Lab Chip, 2026, 26,3069-3082
DOI: 10.1039/D6LC00110F, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Michael Abraham Listyawan, Chi Cong Nguyen, Tran Bach Dang, Nhat Mihn Doan, Quang Anh Nguyen, Yulin Qiu, Eva Tomaskovic-Crook, Mostafa Kamal Masud, Yusuke Yamauchi, Jeremy Micah Crook, Mohit Naresh Shivdasani, Thanh Nho Do, Hoang-Phuong Phan
A scalable fabrication strategy to integrate thin, stretchable mesoporous electrodes onto catheters and soft robotic systems, enabling multifunctionalities including biopotential measurement, electrical stimulation, and bioimpedance sensing.
The content of this RSS Feed (c) The Royal Society of Chemistry

A microfluidic skin-on-a-chip enabling in situ construction of full-thickness human skin for modeling inflammatory diseases

Lab Chip, 2026, 26,3192-3201
DOI: 10.1039/D6LC00189K, Paper

Linwei Sang, Ajing Liu, Junjie Zhu, Qian Yang, Zheng Liu, Shu-Wei Chen, Jinyi Wang
This study presents a detachable microfluidic skin-on-a-chip. Using epidermal–dermal co-culture under dynamic perfusion, the chip enables on-chip construction of inflammatory phenotype and drug evaluation.
The content of this RSS Feed (c) The Royal Society of Chemistry

Porous microneedle-based electrochemical aptamer biosensor for the collection and quantitative analysis of dry eye disease biomarkers

Lab Chip, 2026, 26,3002-3012
DOI: 10.1039/D6LC00230G, Communication

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Eira Beryle Ko, Tianli Hu, Ya Zhang, Xueyan Wang, Yu Song, Chenjie Xu
A porous microneedle-integrated electrochemical aptamer sensor allows for the rapid tear extraction and quantitative biomarker detection in a single device for dry eye disease.
The content of this RSS Feed (c) The Royal Society of Chemistry

Selective on-chip DNA synthesis using electric field-assisted PCR

Lab Chip, 2026, 26,3202-3212
DOI: 10.1039/D5LC01200G, Paper

Doyeon Lim, Youngjun Song
An electric field-assisted PCR platform enables selective on-chip DNA synthesis with precise spatial control using microelectrode arrays. This scalable approach achieves high-efficiency enzymatic synthesis for DNA data storage and diagnostics.
The content of this RSS Feed (c) The Royal Society of Chemistry

LEGO®-inspired electrically-actuated microfluidics for on-chip protein crystallization and in situ X-ray crystallography

Lab Chip, 2026, 26,3213-3228
DOI: 10.1039/D6LC00021E, Paper

Sarthak Saha, Logan Chen, Gabrielle R. Budziszewski, Sara Koprek, Kaleb Seifert, Aina Cohen, Silvia Russi, Sarah E. J. Bowman, Sarah L. Perry
Low-voltage valve actuation to facilitate protein crystallization and in situ X-ray structure determination.
The content of this RSS Feed (c) The Royal Society of Chemistry

Microfluidic well plates integrated with passive nematode culture chambers for multiplexed chemical toxicity assays in C. elegans

Lab Chip, 2026, 26,3083-3101
DOI: 10.1039/D5LC01165E, Paper

Bushra Rahman, Purushottam Soni, Atiyya P. Saroyia, William Schenkenfelder, Siva A. Vanapalli
PNC well plates enable low-intervention, multiplexable C. elegans assays with translational potential for predictive toxicology.
The content of this RSS Feed (c) The Royal Society of Chemistry

Region-specific proteomic profiling of brain interstitial fluid via a micro-invasive sampling platform

Lab Chip, 2026, 26,3153-3167
DOI: 10.1039/D6LC00038J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Qun Cao, Hannah D. Jackson, Aidan J. Duncan, Yufei Cui, Haley O. Higginbotham, Stella Lesnik, Yunseo Jo, Jiaquan Yu, Forest M. White, Michael J. Cima
This study presents a localized, membrane-free method for sampling brain interstitial fluid, enabling high protein yield from small volumes. It uncovers proteomic differences across brain regions, supporting improved biomarker detection.
The content of this RSS Feed (c) The Royal Society of Chemistry

A tunable 50 MHz acoustic vortex tweezer for size-selective manipulation and cell pre-concentration

Lab Chip, 2026, 26,3184-3191
DOI: 10.1039/D6LC00010J, Paper

Xiongwei Wei, Xin Wang, Lili Miao, Yi Quan, Chunlong Fei, Yintang Yang
A tunable 50 MHz silicon metasurface vortex tweezer with M = 1, 3, 5 adjusts capture orbit (50–150 μm), enabling orbital rotation, size-selective manipulation and cell pre-concentration.
The content of this RSS Feed (c) The Royal Society of Chemistry

A compact low-power valveless piezoelectric micropump with a nested rectification structure

Lab Chip, 2026, 26,3128-3138
DOI: 10.1039/D6LC00060F, Paper

Jie Shan, Aoyu Ma, Cuixue Ren, Yuren Zhao, Lixia Yang, Jingmin Li
A valveless piezoelectric micropump with a novel nested rectification structure achieves high net flow rate and low power consumption in a compact design. It shows promising potential for microfluidic chip systems and biofluid transport.
The content of this RSS Feed (c) The Royal Society of Chemistry

Topology-based coordination control for multi-droplet tasks in autonomous digital microfluidics

Lab Chip, 2026, 26,3244-3255
DOI: 10.1039/D6LC00147E, Paper

Kunlun Guo, Zerui Song, Boyi Feng, Tiaofen Qiu, Jiale Zhou, Bin Shen, Bingyong Yan, Zhen Gu, Huifeng Wang
An unmanned topology-based digital microfluidics control system is developed that integrates adaptive path planning with semantic segmentation feedback to achieve fully autonomous coordination of multi-unit droplets with dynamic morphologies.
The content of this RSS Feed (c) The Royal Society of Chemistry

High-throughput microfluidic platform for modelling inflammatory responses of human articular chondrocytes under variable fluid shear stress

Lab Chip, 2026, 26,3112-3127
DOI: 10.1039/D5LC01167A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Aldeliane M. da Silva, Priscila Campioni Rodrigues, Meriem Lamghari, Hoang-Tuan Nguyen, Jere Kettunen, Sebastien Mosser, Prateek Singh, Ali Mobasheri, Gabriela S. Lorite
A scalable, pumpless microfluidic platform applies shear stress gradients and cytokine-driven inflammation to model osteoarthritis physiologically.
The content of this RSS Feed (c) The Royal Society of Chemistry

A compact superlattice as a label-free surface-enhanced Raman scattering substrate for noninvasive urine testing for the diagnosis of lung cancer

Lab Chip, 2026, 26,3102-3111
DOI: 10.1039/D5LC01177A, Paper

Kaili Zhang, Yuancai Ge, Yi Xu, Yujie Liu, Chaoyue Cui, Yuxin Liang, Yangxuan Lin, Jungeng Zhang, Qingwen Zhang, Yi Wang, Xiaoming Lin
A self-assembled compact superlattice is fabricated as a surface-enhanced Raman spectroscopy substrate to distinguish between urine samples from lung cancer patients, post-operative patients, and healthy persons with high accuracy and efficiency.
The content of this RSS Feed (c) The Royal Society of Chemistry

Numerical microfluidic chip modeling of laminar vortex dynamics induced by biomineralization in evolving porous media

Lab Chip, 2026, 26,3020-3038
DOI: 10.1039/D5LC01002K, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Yajie Chu, Dianlei Feng
A 3D numerical microfluidic chip reveals the evolution of precipitation, vortices, and mixing during biomineralization. Precipitate alters pore geometry, inducing vortices that impact mixing.
The content of this RSS Feed (c) The Royal Society of Chemistry

Cell therapy manufacturing at full clinical scale: enhancing the quality CAR-T cell therapy starting materials through massively parallel automated microfluidic cell sorting

Lab Chip, 2026, 26,3229-3243
DOI: 10.1039/D6LC00072J, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Alison M. Skelley, Yasna Behmardi, Luke F. Peterson, David W. Inglis, Mabel Shehada, Laurissa Ouaguia, Khushroo Gandhi, Roberto Campos-González, Tony Ward
Over N = 86 full scale apheresis samples, microfluidic DLD processing yielded significantly higher leukocyte recovery (88% vs. 58%), superior platelet and red blood cell depletion, and reduced CD69⁺ T cell activation compared to conventional Ficoll®.
The content of this RSS Feed (c) The Royal Society of Chemistry

Point of care molecular cancer diagnostics

Lab Chip, 2026, 26,2948-3001
DOI: 10.1039/D5LC01014D, Critical Review

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Seemesh Bhaskar, Saurabh Umrao, Han Keun Lee, Joseph Tibbs, Amanda Bacon, Skye Shepherd, Takhmina Ayupova, Fatma Uysal Ciloglu, Leyang Liu, Anqi Tan, Wang-Chien Chen, My Thi Tra Nguyen, Maria Grace Scannell, Ugur Aygun, Ugur Parlatan, Catherine Zhang, Manish Kohli, Guy R. Adami, Wali Badar, Ron C. Gaba, Aaron Mansfield, Joel Schwartz, Wang Xing, Utkan Demirci, Brian T. Cunningham
Convergent framework for future POC cancer diagnostics aligning clinical needs (why), enabling technologies (how), and translational bridges. It integrates lab-on-chip biosensing and analytics for decentralized, early, longitudinal care.
The content of this RSS Feed (c) The Royal Society of Chemistry

Vacuum-enhanced high-resolution 3D printing yields 11 200 valves and uniform 7 μm isoporous membranes

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00100A, Paper

Dallin S. Miner, Timothy B. Skaggs, Barrett W. Schafer, Heidi E. Hunter, Troy Munro, Adam T. Woolley, Gregory P. Nordin
Vacuum-enhanced high-resolution 3D printing enables scalable, high-density microfluidic fabrication, as demonstrated by the reliable production of 11 200 membrane valves and 198 uniform 7 μm isoporous membranes across the full print area.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Local chemotactic response of Escherichia coli in fluid and near surfaces

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC01048A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Adam Gargasson, Julien Bouvard, Carine Douarche, Peter Mergaert, Harold Auradou
Bacteria can adjust their swimming behaviour in response to chemical variations, a phenomenon known as chemotaxis. Their chemotactic sensibility is logarithmic, and greatly reduced on surfaces.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A microfluidic approach to evaluating surface protection from nonspecific antibody adsorption

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00197A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Yulia Tobolovskaya, Bexi M. Bustillo-Perez, Yingshan Ma, Nadine Löw, Ophélie Zeyons, Daniel A. Richards, Eugenia Kumacheva
A fluorescence assay-based microfluidic approach for real-time studies of the surface adsorption of antibodies and high-throughput screening of anti-biofouling compounds.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Microfluidic insights into microbial impacts on hydrogen flow in underground hydrogen storage

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00206D, Paper

Yuyi Liu, Diansen Yang
Underground hydrogen storage, involving periodic injection and extraction of hydrogen gas, serves as a crucial approach for achieving energy peak shaving and accommodating large-scale renewable energy.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

A parametric study of mechanoporation through microfluidic design to modulate shear, compressive, and adhesion forces and loading rates

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00143B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Avi Gupta, Jacqueline Van Zyl, Collin Bushey, Peter Shankles, Hoseyn A. Amiri, Guillem Pratx, Alexander Alexeev, Todd Sulchek
Narrow, parallelized channels reveal a dynamic loading regime that, when integrated with geometry, flow, single-cell kinematics, and delivery outcomes, defines a mechanistic framework for microfluidic mechanoporation.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Exploring paclitaxel–albumin-loaded neutrophil-like cells via microfluidic-based mechanical deformation for enhanced cargo delivery in glioblastoma therapy

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC01140J, Paper

Daidi Zhou, Xinghua Gao, Zhiyu Mao, Xiaoling Yang, Jingyun Ma, Ekaterina Andreevna Vorotelyak, Guohui Hu, Fengping Zhu, Jinbo Wu
This study investigated the rapid drug delivery capabilities of neutrophil-like cells using a microfluidic chip-based mechanical deformation approach, with an emphasis on glioblastoma treatment at the cellular level.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

High-recovery AAV clarification using a multiplexed spiral inertial microfluidic platform

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC01050K, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Alexander Bevacqua, Do Hyun Park, Sheryar Khan, Qingxuan Li, Mahsa Hadidi, Jianzhu Chen, Jongyoon Han
A 25-layer spiral microfluidic device significantly reduces cell biomass from high-turbidity feedstock using inertial focusing to perform primary clarification and harvest adeno-associated virus (AAV) vectors at 20 mL min⁻¹ with 85% vector recovery.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Experimental diffusiophoresis of porous and non-porous silica particles in dead-end pore microchannel geometry

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC01020A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Mansoureh Rashidi, Matina Nooryani, Giovanniantonio Natale, Anne M. Benneker
The movement of colloids in a solute concentration gradient plays a crucial role in applications, including separations, sorting and reactant transport. We show that porous particles respond different to solute gradients than solid particles.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Creating an improved workflow for paper-based malaria diagnostics by integrating total lysis of whole blood

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00145A, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

J. Prat-Trunas, A. Code, Y. Avalos-Padilla, X. Fernández-Busquets, C. R. Mace, E. Baldrich
Three-dimensional paper-based lysis device fabricated by laser cutting or by wax printing that achieves 100% cellular lysis independent of sample composition, facilitating detection of a malaria biomarker and sample storage for 1 week at RT.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Droplet microfluidic profiling of NK cell cytotoxicity with machine learning-enabled target-cell death analysis

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00301J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Rana S. Ozcan, Fatemeh Vahedi, Shina Namakian, Ali A. Ashkar, Tohid F. Didar
A droplet microfluidic workflow combines ML-based K562 death analysis with manual NK annotation to quantify attachment, killing, serial killing, and killing-time differences across primary, expanded, and tumor-conditioned NK cells.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Development of a 16-channel solid-state nanopore array platform for integrated nanopore fabrication and ionic current measurement

Lab Chip, 2026, Advance Article
DOI: 10.1039/D6LC00216A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Itaru Yanagi, Tadashi Kiyuna, Keiko Esashika, Yoshimitsu Yanagawa, Hai Huy Nguyen Pham, Daiki Kawai, Satoshi Ogihara, Gaku Ogino, Ken-ichi Takeda, Sotaro Uemura
A 16-channel solid-state nanopore array platform enables integrated nanopore fabrication and parallel ionic current measurement.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Highly sensitive wireless dual-spiral resonant contact lens for continuous intraocular pressure monitoring

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC00940E, Paper

Ying Liu, Zhixian Chen, Xiaoyu Zhao, Lin Xu, Shengli Mi
A highly sensitive wireless contact lens featuring an axisymmetric dual-spiral resonator enables continuous, non-invasive intraocular pressure monitoring for glaucoma management.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry

Yield stress fluids in microfluidics: research, applications and opportunities

Lab Chip, 2026, Advance Article
DOI: 10.1039/D5LC00864F, Critical Review

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Hossein Rahmani, Seyed Mohammad Taghavi
Microfluidic technologies support diverse biomedical and environmental applications, many of which involve complex fluids whose non-Newtonian rheology governs small-scale transport, mixing, and interfacial dynamics.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry