RSC - Anal. Methods latest articles

Raman composition analysis of electrolyte solvent mixtures from industrial lithium-ion battery (LIB) recycling

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00600K, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Tom Goldberg, Roland Haseneder, Andreas S Braeuer
We report a Raman spectroscopy method for the quantitative analysis of electrolyte solvent mixtures from industrial lithium-ion battery recycling processes. Compositions of the electrolyte solvent mixtures were evaluated using classical...
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Amino-functionalized bimetallic MOF nanozyme via solvent-assisted ligand exchange for interference-free phenolic detection

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00775A, Paper

Jing Su, Ruiguang Xu, Xinyi Chen, Maolin Zhang, Rongtao Zhang, Qing Han, Artur Cavaco-Paulo, Hongbo Wang
Synthetic route of Cu–Mn NMOF for phenolic detection: precursor Cu–Mn MOF is solvothermally prepared and modified via ligand exchange. Its intrinsic laccase-like activity enables chromogenic reaction between phenols and 4-AP for colorimetric sensing.
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RSM-optimized automated DI-SPME-GC-MS/MS for multi-class trace plasticizers in drinking water

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00322B, Paper

Ying Zhao, Hongfang Gao, Yixin Liu, Wei Wang, Caixia Wang
The simultaneous determination of multiple plasticizers in drinking water remains challenging because of their trace concentrations, diverse physicochemical properties, and susceptibility to background contamination. In this study, an automated direct...
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Low-viscosity hydrophobic deep eutectic solvent based ferrofluid for simultaneous vortex-assisted liquid-liquid microextraction of UV filters and parabens from environmental waters

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00512H, Paper

Kaige Zhang, Yanrong Chen, Jing Wang, Lijun He, Qianchun Zhang
Ferrofluids represent a class of functional materials that combine the flow characteristics of liquids with the magnetic responsiveness of solid magnetic substances. In this study, a novel low-viscosity hydrophobic deep...
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Synthetic blood-based infrared molecular fingerprints: artificial cohorts for methodological research

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D5AY02166A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Niklas Leopold-Kerschbaumer, Nico Feiler, Kosmas V. Kepesidis
Infrared molecular fingerprinting of human blood samples provides a powerful, minimally invasive approach for disease detection and health monitoring.
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Ion exchange enables MALDI-TOF mass spectrometry analysis of sequence-controlled polymers with a positively charged backbone

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00324A, Paper

Bo Zhao, Shengying Cai, Chao Gao
Transforming negative ions of cationic polymers with a positively charged backbone into Tf₂N⁻ or FSI⁻ through an ion exchange reaction makes it possible to achieve MALDI-TOF mass spectrometry analysis.
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Bagging partial least squares for accurate and stable wheat protein content detection using near-infrared spectroscopy

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00743K, Paper

Qingxiao Ma, Longyan Zhang, Yongfeng Ju, Guoao Xie, Feiming Li
The BA-PLS workflow was used for NIR-based wheat protein prediction. The optimal configuration with B set to 5 and a ratio of 0.6 yields superior accuracy, outperforming standard PLS.
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Year classification of high-oleic peanut seeds based on hyperspectral hybrid bands selection method

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00080K, Paper

Hui Shao, Jie Zhao, Chong Chen, Long Sun, Hui Dai, Cheng Wang, Yuxia Hu
Seeds storage-year have a significant impact on high-oleic peanut seed vigor and quality.
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Design, Synthesis and Performance Evaluation of a Fluorescent Probe for the Detection of Sulfur Dioxide In Vitro and Intracellularly

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00623J, Communication

Lin Li, Ning Zhang, Chao Lu, Dan Qiao, Lin-Qing Wang, Linfei Li, Jian-Yong Wang
In this work, a red-emissive fluorescent probe CouS-CN based on a thiophene-coumarin scaffold was developed for the detection of SO₂. The probe exhibits high sensitivity, broad applicability, strong anti-interference performance,...
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Smartphone-Based Colorimetric Analysis of pH Strips Using Machine Learning

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00780E, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Ece Yıldız, Mustafa Şen, Mehmet Akif Özdemir
This study introduces a machine learning (ML)-enhanced smartphone application designed for the precise colorimetric quantification of pH strips. To ensure the robustness of the system against environmental variations, a comprehensive...
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Ultrasensitive SERS-immunochromatographic assay for pesticide detection using core–shell Au@Au nanoparticles: a 103-fold sensitivity boost over LFA

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00530F, Paper

Wangyu Nan, Fan Sun, Qingdan Ye, Qianmin Dong, Kun Pang, Zihong Ye, Kai Sun, Yufeng Wang, Jie huang, Pei Liang
A Novel Surface-Enhanced Raman Scattering-Based Immunochromatographic Assay (SERS-ICA) for ultrasensitive detection of lambda-cyhalothrin in food samples development, validation, and comparative analysis with conventional lateral flow assay.
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Microfluidic-Electrochemical Sweat Patches for Athletes: Monitoring Lactate, Electrolytes, and Hydration Status

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00936K, Minireview

Huibo Liu, Wanglei Lin
Wearable biochemical sensing is shifting sports physiology from intermittent laboratory sampling toward continuous, in situ readouts during training and competition. This review analyzes skin conformal systems that integrate capillary driven...
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Strain-induced PtCu nanozymes for paper-based portable colorimetric immunoassay of carcinoembryonic antigen with smartphone readout

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00867D, Paper

Qingliang Lin, Yibin Zeng, Zhichao Yu, Dianping Tang, Xuejing Wu
This work designed a paper-based portable colorimetric immunoassay of carcinoembryonic antigen using strain-induced PtCu bimetallic nanozymes with smartphone readout.
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Mitochondria-targeted near-infrared fluorescent carbon dots for assessing ATP levels in cardiomyocytes under exercise-simulated metabolic stress

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00721J, Paper

Weilong Zhu, Lin Li, Xiaodong Cheng, Hui Chen
Mit-CDs enable mitochondria-targeted near-infrared imaging and sensitive detection of ATP (LOD 21.3 nM) in cardiomyocytes under metabolic stress.
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Fast Antibiotic Susceptibility Test Integrated Microfluidic Chips for Detection of Carbapenem/Colistin-Resistant Bacteria by a Smartphone- based Analysis

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00313C, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Cagla Celik Yoldas, Nilay Ildiz, Pinar Sagiroglu, Mustafa Altay Atalay, Naim Yağız Demir, Memed Duman, Barbaros Cetin, Ender Yildirim, Gulten Can Sezgin, Yusuf Kenan Genc, Erhan Yoldas, Ismail Ocsoy
Although many phenotypic methods have been developed for the detection of antibiotic-resistant bacteria, this emerging field still requires more rapid, practical, and economic approaches. Herein, we report a colorimetric phenotypic...
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Development of a validated UPLC-MS3 method for trace-level azoxystrobin determination in zebrafish liver tissues

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00445H, Paper

Yufeng Guo, Chunpeng Feng, Lai Mengchuan, Liu Meichen, Yalin Xi, Lei Yin, Meiyun Shi
Azoxystrobin is a widely used strobilurin fungicide. Its environmental persistence and potential toxicity to aquatic organisms demand accurate trace‑level quantification in biological tissues. However, sensitive and specific determination in small...
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Development and validation of LC-MS/MS methods for the quantification of TMS-007, a member of the SMTP congeners, in rat plasma and brain: application to a preclinical pharmacokinetic study

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00057F, Paper

Yuanbin Hao, Yan Zhang, Huaye Gao, Chenjun Wu, Li Sun, Siqi Zhao, Shaofei Xie, Rong Chen
TMS-007 is a member of the SMTP congeners for the treatment of acute ischemic stroke. LC-MS/MS methods to quantify TMS-007 in various rat matrices were developed. The validated methods were applied to a preclinical study in a tMCAO rat model.
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Single-precursor-derived carbon and nitrogen co-doped CuO nanozymes for colorimetric detection of tetracycline

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00592F, Paper

Yu Liu, Jingjing Fang, Liangxiao Jiang, Hengchao Yang, Cheng Yao, Chan Song
The carbon and nitrogen co-doped CuO with high peroxidase-like catalytic activity was constructed via direct pyrolysis of copper(II) phthalocyanine (CuPc) as a single source precursor.
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Synthesis route attribution of highly toxic ethyl sesquimustard based on non-targeted screening strategy and GC-HRMS

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00005C, Paper

Yiming Tian, Yixin Gu, Jianfeng Wu, Jia Chen, Jinqiao Jiang, Yulong Liu, Wei You, Kaikai Li, Jianwei Xie
Synthesis route attribution enables accurate source tracing of Q and effective discrimination between distinct synthetic pathways.
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Natural deep eutectic solvent-based headspace gas chromatography for determination of 14 residual solvents in tea polyphenol products

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00418K, Paper

Hengyu Xu, Zheyuan Yao, Xianyu Bao, Yina Cai, Xiaobo Zuo, Chifang Peng
ChCl–glycerol (1 : 2) was screened as the optimal NADES matrix for HS-GC analysis of residual solvents in tea polyphenols. Risk assessment identified benzene as a critical control point, with dichloromethane (HQ 1.47%) also warranting attention.
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Portable voltammetric determination of acetaminophen using DropSens-based screen-printed carbon electrodes for clinical and pharmaceutical applications

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00692B, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Rocío Navarro-Utiel, Ana Ballester-Caudet, Sergio Cortés-Bautista, Pilar Campíns-Falcó
The increasing demand for portable, low-cost, and sustainable analytical methodologies has motivated the development of miniaturized electrochemical systems for pharmaceutical and clinical monitoring.
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Development of a Colloidal Gold Immunochromatographic Strip for Rapid Detection of Fluoroquinolones in Milk

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00727A, Paper

Mengjuan Zhu, qinggang xu, Yu Shi, Ming Geng, Xun Zhang
Fluoroquinolones (FQs) are widely used in animal husbandry for the prevention of variety of animal diseases. However, if the residues of FQs in animal products that exceed safe limits may...
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Nanobody-Based Enzyme Immunoassay for Naringenin in Pummelos and Herbal Samples

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00451B, Paper

Feng Sun, Chunlei Cao, Jing Zhao, Yue He, Yaohai Zhang, Yongliang Cui, Qiyang Zhao, Jing Li
Nanobodies have emerged as alternatives to conventional antibodies due to their unique advantages. In this study, two naringenin-specific nanobodies, Nb-C9 and Nb-C13, were successfully isolated. The obtained nanobodies demonstrated superior...
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A novel bubble rupture sensing methodology for sweat-driven disease diagnostics

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00583G, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Akshay Ajit Parmar, Anoop Kanjirakat, Dolfred Vijay Fernandes, Naresh Kumar Mani
The ionic strength of sweat fluid influences the bubble bursting time.
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Au@Pt core–shell nanoparticle-based lateral flow immunoassay for rapid detection of Porphyromonas gingivalis type II and IV FimA

Anal. Methods, 2026, 18,4505-4515
DOI: 10.1039/D6AY00298F, Paper

Junheng Chen, Zhenjie Lu, Xiaojun Wang, Fan Cheng, Xudong Wang, Fang Li, Min Li, Yingfu Zhang, Yunlong Wang
Au@Pt core–shell nanoparticle-based lateral flow immunoassay enables 14 min visual detection of Pg FimA II/IV with high clinical concordance for rapid identification of high-virulence periodontal infections.
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Environmentally friendly electrochemical and spectrophotometric strategies for sensitive determination of nintedanib in complex matrices

Anal. Methods, 2026, 18,4494-4504
DOI: 10.1039/D6AY00589F, Paper

Özgür Üstündağ, Marwah Naser, Wiem Bouali, Nevin Erk
Precise quantification of nintedanib (NIN) is essential due to its widespread clinical use and the need for reliable quality control in pharmaceutical and biological samples.
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Microfluidic filtration enrichment cascade nanozyme-catalyzed colorimetric immunoassay for rapid and ultrasensitive detection of Escherichia coli in urine with smartphone readout

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00597G, Paper

Yuancheng Guo, Tianci Wang, Zhijie Tu, Hong Chen, Shengqi Wang, Guohui Sun, Zhen Rong
Escherichia coli in urine can be efficiently filtration enriched for rapid and ultrasensitive nanozyme-catalyzed colorimetric immunoassay.
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COF hybrid fibrous nano-network aided surface-enhanced Raman scattering assay for epinephrine analysis

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00679E, Paper

Tianran Yuan, Xueyan Yang, Yinjia Zhao, Longfeng Chu, Liyan Zheng, Xufang Hu, Jing Hu, Qiue Cao
This work presents a novel COF hybrid fibrous nano-network as a SERS-active substrate for epinephrine detection via boronic acid affinity, using citric acid reporter, enabling sensitive, selective, reproducible detection in serum samples.
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A dual mode turn-on probe for H2O2 sensing via fluorescence and colorimetry in live cells and serum

Anal. Methods, 2026, 18,4433-4443
DOI: 10.1039/D6AY00388E, Paper

Weitian Chen, Hui Dong, Siyu Wang, Yitong Jiang, Yujia Qian, Aixin Chang, Jiahui Ding, Xue Yang, Yanli Zhou, Yintang Zhang, Zhaohui Li, Maotian Xu
Hydrogen peroxide (H₂O₂), as a crucial intracellular reactive oxygen species (ROS) and secondary messenger, plays a key role in various physiological and pathological processes.
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Detection of kanamycin residues in animal-derived foods using a homogeneous AlphaLICA immunoassay

Anal. Methods, 2026, 18,4354-4362
DOI: 10.1039/D6AY00383D, Paper

Dian Li, Shangbin Kao, Yuan Qin, Xiumei Zhou, Xueqin Zhao, Yun Chen, Biao Huang
This homogeneous Kana-AlphaLICA assay enables highly sensitive detection of kanamycin residues in milk and honey within 15 min, providing a rapid tool for high-throughput food safety screening of dairy and apiculture products.
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Phosphate-mediated fluorescence switching in a UiO-66-NH2/red carbon dot hybrid for ratiometric and smartphone-assisted visual detection of ethephon

Anal. Methods, 2026, 18,4423-4432
DOI: 10.1039/D6AY00422A, Paper

Xiao Hu, Rui Pan, Shufei Huang, Yifan Lin, Meizhu Xu, Caiping Yang, Lishuang Yu, Qiang Zou, Huifeng Xu
A smartphone-integrated ratiometric fluorescent platform was developed for on-site quantitative and visual detection of ethephon (ETH) using a UiO-66-NH₂/red carbon dots (R-CD) hybrid probe.
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Responsive red carbon dots with dual-wavelength emission for anti-counterfeiting

Anal. Methods, 2026, 18,4341-4346
DOI: 10.1039/D6AY00700G, Communication

Jingjing Chen, Kaiqing Wu, Mengyi Xi, Jinpeng Cai, Ran Chen, Yanfei Shen, Songqin Liu, Yuanjian Zhang
An anti-counterfeiting strategy based on a hidden spectral switch within red fluorescence is presented, offering a concealed mechanism that fundamentally enhances forgery resistance by maintaining visual constancy under external stimuli.
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Syringe pressure-assisted switchable hydrophilicity solvent microextraction with smartphone digital image colorimetry: a rapid method for trace cobalt determination

Anal. Methods, 2026, 18,4375-4386
DOI: 10.1039/D6AY00606J, Paper

Yingying Zhao, Yi Shi, Jiayi Hu, Fuchun Ji, Xin Liu, Huiqiong Huang, Zhengui Li, Shengchun Yang, Xiaodong Wen
This study first integrates syringe pressure-assisted switchable hydrophilicity solvent microextraction with smartphone digital image colorimetry, enabling on-site determination of trace Co²⁺ in water and other samples.
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DNAzyme–aptamer electrochemical biosensor for Pb(II) and Hg(II) determination: robust validation in food matrices and water samples

Anal. Methods, 2026, 18,4444-4453
DOI: 10.1039/D6AY00231E, Paper

Chang Su
Dual-mode graphene oxide–gold nanoparticle biosensor detects Pb²⁺ and Hg²⁺via DNAzyme cleavage (signal decrease) and aptamer folding (signal increase); validated in water, milk, fish, and spinach.
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High-frequency ammonium monitoring in coastal seawater via a flow-batch system featuring a heating reaction coil

Anal. Methods, 2026, 18,4516-4522
DOI: 10.1039/D6AY00478D, Technical Note

Fanrong Zeng, Kunning Lin, Yuanbiao Zhang
Ammonium (NH₄⁺) is a critical nutrient in marine ecosystems, and its high-frequency monitoring is essential for understanding dynamic biogeochemical processes.
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Waste-derived chlorogenic-acid Ag nanozyme for nanomolar dopamine sensing in pharmaceutical formulations

Anal. Methods, 2026, 18,4400-4413
DOI: 10.1039/D6AY00337K, Paper

Anurag Phukan, Maga Nana Kaka, Moushumi Hazarika, Abhishek Borborah, Manash R. Das, Chandan Tamuly
Biosynthesized nanozymes are attractive for low-cost dopamine sensing, yet most reported systems rely either on synthetic nanomaterials or poorly defined “green” extracts, which limits sustainability, reproducibility, and translational relevance.
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HCR signal amplification strategy based photothermal sensing for histamine detection

Anal. Methods, 2026, 18,4347-4353
DOI: 10.1039/D6AY00601A, Paper

Huiling Xue, Bing Zhang, Ying Zhan, Zhihuan Zhao, Jianying Lin, Yan Cheng
A photothermal aptamer biosensor was built for detecting histamine using HCR amplification and CuS@Au nanocomposites and quantified through the thermometer.
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Paper-based colorimetric test strip for arsenic detection in vegetable oils

Anal. Methods, 2026, 18,4414-4422
DOI: 10.1039/D6AY00310A, Paper

Zhipeng Cai, Liuping Zhang, Jiaxun Li, Lingling Guo, Chuanlai Xu, Hua Kuang
Arsenic, a potent carcinogen, easily accumulates in vegetable oils, therefore, we developed a colorimetric test strip for arsenic detection in vegetable oils based on the Gutzeit method.
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Construction of a highly sensitive electrochemical sensing platform using an Au–RGO–MWCNTs nanocomposite for the synergistic amplification of rutin detection

Anal. Methods, 2026, 18,4454-4465
DOI: 10.1039/D6AY00661B, Paper

Ling-Zhi He, Xiang Li, Zhi-Wen Zeng, Yang Hong, Chi-Qiong Liu, Zhong-Hou Liang, Wen-An Kuang
This work reports the facile construction of an Au–RGO–MWCNTs modified electrode and its application in the electrochemical sensing of rutin.
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Selection and characterization of DNA aptamers specific to trichlorfon

Anal. Methods, 2026, 18,4466-4474
DOI: 10.1039/D6AY00588H, Paper

Shuting Yang, Dan Wei, Ziyu He, Li Li, Tong Zhou, Xueying Liu, Yan Deng
Schematic diagram of the capture-SELEX principle and the APTri-7/BP/PLL/AuNPs/GCE sensor manufacturing process.
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An advanced GC method for comprehensive residual solvent analysis: overcoming co-elution with orthogonal columns and quantification by mass spectrometry

Anal. Methods, 2026, 18,4475-4485
DOI: 10.1039/D5AY01603G, Paper

Ruba Arulraj, Vinay Vishwanath, Sharad Duche, Arvind Mathur, Amrita Roy
A robust and comprehensive gas chromatographic method was developed to identify and quantify the 57 residual solvents listed in the ICH guidelines, all in a single, 30-minute chromatogram.
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A novel peroxidase-mimicking Cu,S co-doped carbon dot nanozyme for dual-mode lactate biosensing in serum and sweat

Anal. Methods, 2026, 18,4387-4399
DOI: 10.1039/D6AY00462H, Paper

Ali M. Alaseem, Glowi Alasiri, Razan Orfali, Ramadan Ali, Al-Montaser Bellah H. Ali, Mohamed M. El-Wekil
A novel biosensor was proposed for dual-mode detection of lactate in serum and sweat samples. It is based on Cu–S@CDs and surprisingly shows peroxidase-mimicking activity.
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Development and validation of an LC-MS/MS/MS method for the sensitive quantification of trace β-agonists in complex animal-derived food matrices

Anal. Methods, 2026, 18,4363-4374
DOI: 10.1039/D6AY00363J, Paper

Chujun Liu, Jiankang Ren, Qian Ran, Yuliang Xu, Boyan Sun, Zhiyue Feng, Sihan Wang, Jie Xie, Haiyang Jiang
The LC-MS³ method, which overcomes matrix interference and enhances selectivity, sensitivity, and specificity through its multi-stage fragmentation capabilities, was first applied to simultaneously quantify nine β-agonists in high-fat milk and pork.
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Quantitative determination of maslinic acid and oleanolic acid in olive pomace using high-speed shear extraction and liquid chromatography

Anal. Methods, 2026, 18,4486-4493
DOI: 10.1039/D5AY01925G, Paper

Sheng-Bing Wang, Kun Yang, Dong Pei, Lu-Mei Pu, Xin-Yi Huang
Olive pomace contains abundant maslinic acid and oleanolic acid, which are pentacyclic triterpenoid compounds with excellent biological activity.
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Automated SPE-GC-MS/MS method for the biomonitoring of eight N-nitrosamines in human urine

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00432F, Paper

Wanjun Zhang, Run Zhou, Xiangyu Wang, Chao Yang, Chunhua Huang, Xinliang Ding
A highly automated SPE-GC-MS/MS workflow was developed for sensitive biomonitoring of eight N-nitrosamines in human urine using only 4 mL of sample.
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Real-time resonance Raman spectroscopic monitoring of the Briggs–Rauscher reaction

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00742B, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Clark D. Gray, Nigel Gotts, Cassio Lima, Kenneth Williams, Sebastien Maussang, Royston Goodacre
The Briggs–Rauscher reaction is a prototypical oscillating system and is based on chemical mixtures of iodate (IO₃⁻), hydrogen peroxide, malonic acid and Mn²⁺ ions in an acidic solution.
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Real-time detection of microbial aerobic plate count in salmon fillets based on near-infrared-hyperspectral imaging

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00582A, Paper

Min Chen, Xiaoting Huang, Jiayi Li, Lijun Yao, Tao Pan
The innovative near-infrared-hyperspectral imaging modeling method incorporating spectral preprocessing and wavelength optimization was proposed, enabling real-time quantitative analysis and exceedance discrimination for the APC in salmon fillets.
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The development of aptamer-functionalized streptavidin magnetic particles for sample purification of SARS-CoV-2 coupled with rapid plasmonic RT-qPCR to improve detection sensitivity

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00498A, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Joshua Hayes, Alex Resendes, Seung Soo Lee, Mitra Yousefi, Silvia Vidal, Miltiadis Paliouras, Mark Trifiro
Schematic diagram of the development of an aptamer-based capture methodology for the rapid enrichment and diagnostic sensitivity with plasmonic PCR of SARS-CoV-2.
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A simple method for quantifying microplastics in water utilizing hydrophobic dyes via ultraviolet-visible spectrophotometry

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00831C, Paper

Yuechuan Luo, Yiping Li, Bangyan Ou, Ruotong Yang, Guoyu Qiao, Zhenggang Wang
A novel method for the microplastics quantitative detection was developed, based on hydrophobic dye staining and spectrophotometry. The staining process exhibited good linear relationship and anti-interference capability.
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Non-enzymatic electrochemical detection of hemoglobin via analyte-triggered in situ phase transformation of β-Ni(OH)2 nanosheets

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00617E, Paper

Priya Pathmanathan, Harshit Kale, Shourya Singh Thakur, Madhavan Ramasubramani, A. Gomathi
Haemoglobin (Hb) is the principal diagnostic biomarker for anemia, which affects over one billion people globally and poses a critical public health burden in low- and middle-income countries.
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A rapid, multiplex, one-pot CRISPR/Dx system for visual detection of influenza A, influenza B, and respiratory syncytial viruses

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00425C, Paper

Qiyuan Xia, Rui Guo, Jianrong Xiao, Lu Zeng, Yumei Huang, Jiahui Li, Xiaoqing Chen, Tingting Huang, Bing Xiao, Chenyu Miao, Weihuang Liu, Qing-Le Liang, Cia-Hin Lau, Haibao Zhu
Multiplex detection of influenza A virus (IAV), influenza B virus (IBV), and respiratory syncytial virus (RSV) with one-pot RT-RPA-CRISPR/Cas12a system.
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Recent advances in microfluidic technologies for circulating tumor cell isolation: from separation strategies to clinical translation

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00687F, Critical Review

Chentao Li, Jialuo Cheng, Dingfu Zhao, Rui Cao, Yinglin Wang, Siyuan Zhao, Dezhi Li, Qing Liu
Microfluidic technologies isolate rare circulating tumor cells through physical, affinity-based and surface-engineered strategies, enabling downstream molecular analysis and clinical translation.
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Integration of paper-based DNA extraction with digitized image analysis for colorimetric LAMP-based V. parahaemolyticus detection

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00702C, Paper

Thi Ngoc Diep Trinh, Nguyen Tran Truc Phuong, Kien Cuong Tran, Kieu The Loan Trinh, Hanh An Nguyen
A novel approach integrating paper-based DNA extraction with digitized image analysis – assisted colorimetric LAMP was developed for colorimetric detection of Vibrio parahaemolyticus.
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An exonuclease III-assisted CHA dual-cycle amplification strategy for quencher-free fluorescent detection of miRNA

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00629A, Paper

Shi-Qian Liao, Jia-Hao Liu, Xin-Yue Liu, Yi-Ting Liu, Chun-Guang Yang, Zhang-Run Xu
A simple, sensitive, and quencher-free fluorescent method for miRNA detection by combining catalytic hairpin assembly (CHA) with exonuclease III (Exo III)-assisted signal amplification.
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Screening of aggregation properties of cyclic peptides by protein nanopores

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00427J, Communication

Hang Yang, Wenqi Lu, Dongdong Wang, Xiaoyu Zhang, Zan Li, Minmin Li, Haijuan Qin, Jiaqi Li, Guangyan Qing
Nanopore sensing explores the aggregation behaviors of cyclic peptides, unveiling distinct ionic current signatures and insights into their structural dynamics.
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A novel CRISPR/Cas14a-synergized wood-based platform for the ultrasensitive detection of aflatoxin B1

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00717A, Communication

Huixin Chen, Qing Li, Xun Mao
A CRISPR/Cas14a-synergized wood-based platform was constructed by establishing a sandwich-type strategy integrated with a smartphone imaging and analysis for the highly sensitive quantitative detection of AFB1.
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Determination of short-chain chlorinated paraffins in carpets by gas chromatography-electron capture negative ionization mass spectrometry

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00647G, Paper

Ting Gu, Yongli Wu, Lianrui Mei, Yu Zhang, Yi Han
A method based on GC-ECNI-MS was developed for determining short-chain chlorinated paraffins (SCCPs) in carpets, offering data support for global risk control of SCCPs use in carpet products.
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Sensitive and reliable Kawasaki disease related microRNA analysis via self-priming chain extension cascades

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00576D, Paper

Qiuling Huang, Jia Yang
Kawasaki disease (KD) is a leading cause of acquired heart disease in children, requiring timely diagnosis.
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Domain-Adaptive Raman Spectral Calibration Transfer for Cross-Instrument Glioma Detection

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00651E, Paper

Qingbo Li, Yefan Zhang, Xupeng Shao, Zhiqi Zhou, Yan Zhou, Jingying Jiang, Hongbo Bao, Zeya Yan, Wenjun Tu, Ping Feng, Lipu Zhou
Glioma, a highly invasive tumor of the central nervous system with poor prognosis, requires accurate detection for effective clinical management, where rapid and precise tissue discrimination plays a critical role....
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Metal-free miniaturized flexible electrochemical sensors based on nitrogen-doped carbon black for liquid crystal monomer detection

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00087H, Paper

Xiuying Li, Zhi Li, Zilong He, Fengyu Li
A miniature, portable detection system based on a flexible electrochemical sensor was developed using metal-free nitrogen-doped carbon black for field detection of liquid crystal monomers.
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Hexafluoroisopropanol-induced salt-free catanionic surfactant supramolecular solvent for direct immersion single-drop microextraction of sulfonamides and fluoroquinolones in water samples

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00449K, Paper

Keke Huang, Jia Chen, Wending Yao, Xiao Li
A homemade DI-SDME holder stabilizes high-density HFIP-induced salt-free catanionic surfactant SUPRAS droplets, enabling simple, sensitive and green trace analysis of sulfonamides and fluoroquinolones in water samples.
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Stabilization of a ring-opened rhodamine probe via multi-noncovalent interactions for the dual-mode detection of nitazenes

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00429F, Paper

Yujie Feng, Yudong Li, Bingbing Zhao, Chuanfang Zhao, Jingxiang Li, Luyan Yang, Baiyi Zu, Xincun Dou
Nitazene opioids, representing a potent class of emerging synthetic substances, have emerged as a significant threat to public health and biosafety worldwide.
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Nanozyme-enhanced lateral flow immunochromatographic tests for the sensitive detection of Francisella tularensis cells in water samples

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00561F, Paper

Nadezhda Byzova, Olga Hendrickson, Vasily G Panferov, Alexey A. Gorbatov, Anton G Shevyakov, Sergey F. Biketov, Anatoly V. Zherdev, Boris B. Dzantiev
Francisella tularensis is a bacterial pathogen that can contaminate drinking water and food products, causing tularemia – a severe zoonotic disease that affects both humans and animals. This infection is...
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Application of surface-enhanced Raman spectroscopy in the diagnosis of infectious diseases

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00691D, Minireview

Lili Tian, Yanxi Li, Tao Wang, Jie Gong, Junbo Han, Jingdong Yuan, Jin Chen, Huiping Zhang, Lihua Qian
Surface-enhanced Raman spectroscopy (SERS) is increasingly emerging as a pivotal analytical technique in the field of clinical diagnostics.
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Smartphone Integrated Portable Oxidase-like Hydrogel Kit for UO2 2+ Colorimetric Analysis

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00461J, Paper

Ruotong Liu, Yu Qiao, Zhongke Hu, Dandan Xu, Xiao-Qiong Li, Hang Gao, Bin Liu
Uranyl ion (UO₂²⁺) pollution in marine environments poses a serious threat to human health and aquatic ecosystems. To overcome the dependence of traditional detection methods on large-scale instruments, a portable...
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Advancements of plant-based materials for Sustainable Health Applications

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D5AY02086G, Critical Review

Meenakshi Choudhary, Dharmesh Kumar, Penny P Govender, Sudheesh Shukla
Biosensing technologies play a critical role in various fields, including healthcare, environmental monitoring, and food safety. In-vivo sensing of biomolecules is challenging due to the non-biocompatibility of nano or microelectrodes....
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A CHEF-driven fluorescent turn-on probe for sensitive and rapid Al3+ detection in live MDA-MB-231 cells

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00264A, Paper

Rahul Naskar, Gita Rani Murmu, Subrata Mandal, Rimi Mukherjee, Arpan Halder, Amitav Biswas, Moumita Ghosh, Saswati Gharami, Nabendu Murmu, Tapan K. Mondal
A novel fluorescent switch (PIMB) has been fabricated through a straightforward Schiff base reaction and exhibits highly selective sensing of Al³⁺ over other metal ions at physiological pH.
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A new strategy for improving the precision and accuracy of isotope ratio analysis by quadrupole ICP-MS with the optimization of ion beam trajectory

Anal. Methods, 2026, 18,4145-4153
DOI: 10.1039/D6AY00371K, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Xing Li, Haitao Li, Dingwen Zhang, Xin Yang, Yu Cui, Wei Guo, Lanlan Jin, Shenghong Hu
A new strategy is proposed to improve the accuracy and precision of isotope analysis using ICP-QMS by controlling ion motion trajectories and reducing mass discrimination.
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A magnetic separation-based dual-mode aptasensor integrating FRET fluorescence and UV absorption for early diagnosis of hepatocellular carcinoma

Anal. Methods, 2026, 18,4200-4210
DOI: 10.1039/D6AY00682E, Paper

Jianghua Wang, Jianfeng Tang
Early diagnosis of hepatocellular carcinoma (HCC) is crucial for improving patient survival; however, conventional detection methods using HepG2 cells (a typical HCC cell line) have inherent limitations.
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Construction of viscosity-sensitive RNA fluorescent probes and their application in inflammtation imaging

Anal. Methods, 2026, 18,4189-4199
DOI: 10.1039/D6AY00370B, Paper

Meini Tang, Enxiang Ge, Guofang Li, Dingkun Xiong, Weiying Lin
Abnormal structure or function of the nucleolus can lead to dynamic imbalances in intracellular viscosity, which is a core pathological feature of major diseases, including inflammation and cancer.
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Nanomaterial-enhanced molecular recognition: a Co3O4/TiO2 heterojunction electrochemical sensor for vanillin with experimental and DFT insights

Anal. Methods, 2026, 18,4300-4319
DOI: 10.1039/D6AY00358C, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Favour Ezinne Ogulewe, Akeem Adeyemi Oladipo, Mustafa Gazi
A DFT-supported Co₃O₄/TiO₂ heterojunction molecularly imprinted sensor provides highly selective, synergistic electrochemical determination of vanillin in complex food matrices.
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Application of a fluorocarbon chain derived silica as a dispersive solid-phase extraction sorbent for six PAEs in water samples

Anal. Methods, 2026, 18,4183-4188
DOI: 10.1039/D6AY00365F, Paper

Yi-Yang Fang, Hai-Yan Liu, Zhi-Guo Shi
A dispersive solid-phase extraction method was established. And a type of fluorocarbon chain derived silica that can be easily dispersed into water was synthesized. Six PAEs were extracted via polar–polar and hydrophobic interactions.
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Target-to-signal conversion and spatial enrichment cascade boost CRISPR/Cas12a biosensing for trace-level pathogen detection

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00441E, Paper

Yu Liu, Xudong Yue, Bowen Li, Haoyu Yang, Yu Wang, Shenguang Ge, Su Liu
A CRISPR/Cas12a-activated DNA nanowire biosensor has been developed for the highly sensitive detection of Salmonella typhimurium.
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Simple yet sensitive MicroRNA detection using allosteric probe-initiated triple amplification and Cas13a/crRNA-based amplification reaction

Anal. Methods, 2026, 18,4154-4160
DOI: 10.1039/D6AY00578K, Paper

He Chen, Chaonan Zhang
MicroRNAs (miRNAs) have emerged as promising biomarkers for early diagnosis and management of degenerative disc disease (DDD); however, their low abundance and high sequence homology pose significant challenges for clinical detection.
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Fluorescence sensor array integrated with machine learning: robust discrimination of multiple metal ions using carboxyl-rich carbon dots

Anal. Methods, 2026, 18,4133-4144
DOI: 10.1039/D6AY00272B, Paper

Yixiang Li, Weidong Zhang, Da Chen, Xiaobo Sun, Chun Li, Baomin Yang, Jinping Wang
Carboxyl-rich carbon dots combined with six chemically distinct pH 5.0 media generate orthogonal fluorescence fingerprints, enabling machine-learning-assisted discrimination of 15 metal ions and their mixtures in complex environmental samples.
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Analytical workflows in salivary metabolomics for athlete stress monitoring: sampling, platform selection, and translation challenges

Anal. Methods, 2026, 18,4111-4132
DOI: 10.1039/D6AY00755D, Minireview

Fei Liu, Xiaotian Gao, Xiaoping Wang, Song Yuan, Chan Wang
Salivary metabolomics offers a low-burden biochemical layer for athlete monitoring, but translation requires standardized analytical workflows suitable for repeated real-world use.
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Simultaneous determination of eight cannabinoids in hemp-based dietary supplements via an optimized SE-HPLC-PDA workflow integrating chemometric evaluation

Anal. Methods, 2026, 18,4171-4182
DOI: 10.1039/D6AY00387G, Paper

Radosław Porada, Monika Wójcik, Małgorzata Herman, Wojciech Piekoszewski
The growing availability of hemp-based dietary supplements requires improvement of analytical methods and sample preparation for quality control of such products.
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Quantification of multi-volatile compounds in cooked rice by using headspace solid-phase microextraction coupled to gas chromatography-mass spectrometry

Anal. Methods, 2026, 18,4289-4299
DOI: 10.1039/D6AY00201C, Paper

Xianqiao Hu, Shuimei Li, Lin Lu, Weixing Zhang, Linping Zhang, Mingxue Chen
Quantification of multiple volatile compounds in cooked rice was performed using HS-SPME-GC-MS. Standard addition was used to eliminate the matrix effect, and a reference compound was introduced to improve the linearity of the calibration curve.
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A molecular-imprinted SERS sensor based on a silver substrate for the selective capture and sensitive detection of crystal violet in textile wastewater

Anal. Methods, 2026, 18,4277-4288
DOI: 10.1039/D6AY00255B, Paper

Xiaohui Ren, Kailai Zhang, Jiaying Dou, Fei Xue, Xinyu Liu, Chenhui Yin, Wenjie Ma
The ploymerization, eluting and rebinding process of Ag@MIPs.
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Chemical derivatization of citrullinated peptides using methylglyoxal and sodium 3-mercaptopropanesulfonate (MG/MPS)

Anal. Methods, 2026, 18,4320-4330
DOI: 10.1039/D6AY00547K, Paper

Yunxia Wang, Juanjuan Zhao, Shan Zhang, Ying Wang, Zhibo Jin, Xingtai Qiu, Zichao Tang, Nan Deng, Yangyang Bian
A novel MG/MPS derivatization strategy is established for highly specific and sensitive analysis of protein citrullination by mass spectrometry.
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A quinoxaline-based conjugated microporous polymer-coating for solid phase microextraction of polycyclic aromatic hydrocarbons in environmental samples

Anal. Methods, 2026, 18,4236-4248
DOI: 10.1039/D6AY00360E, Paper

Gang Xiang, Liushi Xu, Zheng Li, Fengping Liu, Huan Lian, Cuizhong Zhang, Jing Sun, Jinyun Peng, Yunyu Li
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants with severe ecological toxicity, released via both biogenic and anthropogenic pathways.
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Development and validation of a cross-species breath metabolomics platform for translational VOC analysis

Anal. Methods, 2026, 18,4263-4276
DOI: 10.1039/D6AY00164E, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Zhiheng Yu, Yongyan Ji, Zijun Meng, Xiang Li
A validated cross-species breath metabolomics platform enables transferable VOC discovery from human studies to animal model verification.
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Single-probe cascade determination of multiple analytes by a tandem reaction of copper nanoclusters

Anal. Methods, 2026, 18,4211-4216
DOI: 10.1039/D6AY00117C, Paper

Bo Zhao, Huijun Zhang, Liuyang Wang, Weiping Chen, Liping Fang, Xinwu Ba, Libin Bai
Fluorescent and colorimetric dual-channel determination of hyperoxide and R-COOH by a tandem reaction of copper nanoclusters.
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A ratiometric fluorescence sensor based on a bifunctional Cu-MOF nanozyme for dual-signal detection of glyphosate in actual samples

Anal. Methods, 2026, 18,4161-4170
DOI: 10.1039/D6AY00220J, Paper

Yubo Zhang, Chao Liu, Huihui Ge, Tianyi Zheng, Jianhua Wang, Yaoyong Wang
Schematic diagram of dual-function nanozyme detection of GLY.
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Digital image method based on a smartphone assisted by hydrophobic natural deep eutectic solvent for iron quantification in dietary supplements

Anal. Methods, 2026, 18,4249-4262
DOI: 10.1039/D6AY00456C, Paper

Gabriel Bercley de Lima Vitorino, Jackson Rodrigo dos Santos Silva, Vinícius de Alcântara Carvalho, João Paulo Barbosa de Almeida, Willian Toito Suarez, Severino Carlos Bezerra de Oliveira, Vagner Bezerra dos Santos
Extraction and detection of iron from supplementary materials using natural deep eutectic solvents and the digital image method.
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Rapid identification of chemical constituents of Liaogu formula based on UHPLC-Q-TOF-MSE combined with the UNIFI platform

Anal. Methods, 2026, 18,4217-4235
DOI: 10.1039/D5AY02031J, Paper

Xin Li, Caiying Liu, Liqi Ng, Qiujia Yu, Yingtao Bai, Yu Zhou
Chemical components of Liaogu Formula (LGF) were analysed using ultra performance liquid chromatography-quadrupole-time of flight-mass spectrometry (UHPLC-Q-TOF-MS^E) combined with the UNIFI platform.
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A two-stage signal enhancement method integrating the Gaussian mixture model and adaptive rolling ball technique for ultrasensitive fluorescent immunochromatographic detection

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00496B, Paper

Qian Bian, Chongwen Wang, Wenlong Bai, Liping Dai, Tao Zhang, Qian Wang, Long Zhang, Shuai Zheng, Shu Wang
A portable fluorescence detector with GMM-ARB two-stage enhancement achieves ultrasensitive pathogen detection.
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Reaction-induced fluorogenic sensing of benzodiazepines: a 3D-printed smartphone-based device with multivariate RGB optimization

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00325G, Paper

Thiago Alvares Zamaro de Freitas, Matheus Martins Guedes, Camilla Fonseca Silva, Marcella Matos Cordeiro Borges, Álvaro Cunha Neto, Josefredo Rodriguez Pliego, Cleocir José Dalmaschio, Keyller Bastos Borges
A portable 3D-printed smartphone fluorimetric platform enables benzodiazepine detection with multivariate RGB optimization (MLR: R² = 0.9998), achieving laboratory-grade analytical performance with field-deployable simplicity.
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A pathogen-activated DNAzyme triggers hybridization chain reaction for ultra-sensitive salivary detection of Helicobacter pylori

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00648E, Paper

Qiming Chen, Quanling Dong, Zhengrong Lu, Zhanmin Liu
Helicobacter pylori infection is a major etiological factor in chronic gastritis, peptic ulcer disease, and gastric cancer, highlighting the demand for sensitive, non-invasive, and operationally simple diagnostic strategies.
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Development of a bioluminescent enzyme immunoassay for glycocholic acid based on a single-chain variable fragment-nanoluciferase fusion

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00731G, Paper

Yunping Mu, Huajian Cai, Xindan Zhang, Mingxia Lin, Junhao Zeng, Yiyun Wang, Ziming Wu, Suqing Zhao, Xiping Cui
As glycocholic acid (GCA) has been recognized as a biomarker for hepatocellular carcinoma (HCC), its detection is crucial for the prevention, diagnosis, and treatment of HCC.
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Rational design of L-histidine-stabilized fluorescent copper nanoclusters for highly selective and sensitive detection of sunset yellow

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00800C, Paper

Xingwu Li, Xiaotian Liu, Lili Yuan, Zhengshan Tian
The water-soluble, blue-green fluorescent copper nanoclusters demonstrate exceptional stability in high-temperature and high-salt environments, overcoming the limitations of many fluorescent probes in complex matrices.
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Mahonia-Derived Carbon Dots for Dual-Ion Ratiometric Sensing and Cellular Bioimaging

Anal. Methods, 2026, Accepted Manuscript
DOI: 10.1039/D6AY00783J, Paper

Shuo Yang, Qiushu Chen, Manshan Liang, Shangheng Huang, Yuli Mei, Kaisong Yuan, Shengfeng Huang, Yang Huang
The presence of hexavalent chromium (Cr6+) and silver ions (Ag+) in pharmaceutical systems poses significant safety concerns due to their toxicity and bioaccumulation potential. Therefore, the development of rapid, reliable,...
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Smart dual-wavelength UV-vis spectroscopic method and smartphone-based RGB method for the rapid quantification of pyronaridine tetraphosphate: integration with the SDG approach

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00052E, Paper

Jenish H. Parekh, Abhishek Munjapara, Bhavesh N. Socha, Subrata Patra, Hetal Jebaliya
This study demonstrates the quantification of pyronaridine tetraphosphate using UV-Vis spectroscopy and a smartphone-based method with the integration of an SDG approach.
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A nitrogen-doped carbon dot fluorescent probe for sensitive detection of metronidazole in pharmaceutical samples and evaluation of its cytotoxicity and cell imaging performance

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00354K, Paper

Jiahui Li, Jingui Zhong, Hanyan Wei, Hongyan Bai
Metronidazole (MTZ) is a widely used nitroimidazole antibiotic, and its excessive use may pose health risks.
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Iodine-starch reaction renewed: determination of iodate in table salts via the lab-in-syringe technique

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00438E, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Cemre Yıldız, Ivana H. Šrámková, Sercan Yıldırım, Petr Solich, Burkhard Horstkotte
A novel in-syringe automated method was developed for simple, sensitive, and green determination of iodate in table salts.
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Recovery of TNT from post-blast soil samples: effects of soil type, extraction methodology, and storage conditions

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00563B, Paper

Open Access

This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

A. J. Hecker, H. Upadhyaya, J. V. Goodpaster
Traditionally, determination of explosives and their decomposition products in soil samples involves a 24-hour ultrasonic solid–liquid extraction (SLE) using acetonitrile followed by a “salting out” liquid–liquid extraction (LLE).
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A polymer-integrated flexible gold nanotriangle array for quantitative and nondestructive SERS detection of thiram on apples

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00537C, Paper

Ze-Bo Zheng, Xiao-Hui Sun, Wan-Hui Guo, Wen Pan, Fan-Li Zhang, Sheng-Hong Liu
Polymer-integrated flexible SERS platform for nondestructive detection on non-planar food surfaces.
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A zwitterionic-enabled one-pot electrochemical strategy for stable end-point detection of isothermal nucleic acid amplification

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00543H, Paper

Yijie Wang, Yang Li, Jiufa Zhang, Mingjun Cai, Qi Fu, Xiaohan Lin, Cuiping Ma, Chao Shi
A zwitterionic EC-LAMP strategy enables stable end-point electrochemical detection of isothermal nucleic acid amplification by reducing interfacial fouling.
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Direct inlet probe mass spectrometry with wavelength selective resonance enhanced photo ionisation

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00377J, Paper

Open Access

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Fabian Etscheidt, Philip Jürß, Christopher P. Rüger, Ralf Zimmermann
We demonstrate a wavelength-selective atmospheric-pressure laser ionisation (APLI) workflow for direct inlet probe (DIP) evolved-gas analysis with ultra-high-resolution mass spectrometric detection.
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Analytical method development for multiresidue determination in water using automated parallel dispersive pipette extraction and HPLC-DAD

Anal. Methods, 2026, Advance Article
DOI: 10.1039/D6AY00396F, Paper

João Pedro Ossucci Martins, Augusto Bortolotto, Francielle Crocetta Turazzi, Lucas Morés, Eduardo Carasek
This work presents an automated parallel dispersive pipette extraction (Au-Pa-DPX) technique for analyzing nine organic compounds from different classes in river water.
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