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Synthetic Reaction Updates is a literature alerting service keeping you up to date with recent developments in synthetic organic chemistry. Covering a wide range of primary sources, Synthetic Reaction Updates includes the most important and exciting reactions published in the recent scientific literature. The updates are presented as easily readable reaction schemes and are also searchable by topic and reaction type. Subscribers can set up personalised searches and receive alerts of the latest developments directly via email. Synthetic Reaction Updates replaced Methods in Organic Synthesis and Catalysts & Catalysed Reactions in 2015.


Synthetic Reaction Updates covers a broad range of primary research published in general chemistry and organic chemistry journals. Our Scientific Editors identify the most interesting, novel and relevant reactions, tailoring the selection of articles with synthetic organic chemists in mind. The range of journals included can be seen in the source list.

Information provided by Synthetic Reaction Updates

Each record in the update provides a redrawn reaction scheme with full bibliographic information for the original article. There are also direct links to the publisher’s website where the article can be downloaded. Bibliographic information can be imported into citation management programmes, and the reaction schemes downloaded. Reactions are also classified by reaction type to allow easy browsing.

Email alerts

Personalised searches can be saved to a user’s profile and used to create automatic email alerts that will send details of recently added reactions without having to perform a new search. Readers can also sign up to weekly or monthly updates to browse when they choose.

Scientific Editors

Our Scientific Editors select the most interesting and useful reactions from the recently published scientific literature to include in Synthetic Reaction Updates.

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Nessa Carson, Pfizer, UK

Nessa Carson was born in Warrington, England. She received her MChem degree from Oxford University, before completing postgraduate studies at the University of Illinois at Urbana-Champaign in 2016. She started in industry as a synthetic chemist for AMRI in 2017, then moved within the company to run the high-throughput automation facility on behalf of Eli Lilly in Windlesham. Nessa started at Pfizer as a high-throughput chemist in 2019. She is interested in developing computer-based tools to optimize efficiency in chemical workflows, and maintains a website of useful chemistry resources

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Gang Deng, Janssen Shanghai R&D Center, P. R. China

Gang Deng completed his B.S. degree at Shenyang Pharmaceutical University. He worked under the guidance of Prof. Yuan-Chao Li, Shanghai Institute of Materia Medica, on organic methodology, receiving his Ph.D. degree in 2007. After the China Postdoctoral Science Foundation postdoctoral stint with Prof. Biao Jiang at the Shanghai Institute of Organic Chemistry on bio-active compound synthesis, he joined Prof. David Lee’s lab at Massachusetts General Hospital in Boston, USA as a postdoctoral researcher working on discovery of novel psychoactive agents. In 2011, he joined Prof. Michael Jung’s group at the University of California, Los Angeles where he developed bio-active small molecules with various activities. In 2014, he joined the AbbVie Shanghai R&D Center and after the shutdown of the research center, he joined Haiyan Pharma for two years. In late 2016, Dr. Deng joined Janssen Shanghai R&D Center as Sr. Medicinal Scientist.

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Zheng Li, Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences (CAS), P. R. China

Zheng Li obtained her Ph.D degree in 2010 from Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), under the guidance of Prof. Yuan-Chao Li. She joined Prof. Yoshito Kishi’s lab at Harvard University as a postdoctoral researcher in Jun of 2010. From 2012 to 2014, she worked at the Department of Molecular & Medical Pharmacology, University of California, Los Angeles in Prof. Caius G. Radu’s lab, where she developed several small molecule inhibitors of the nucleoside salvage enzyme deoxycytidine kinase (dCK) as potential cancer therapeutics. In 2015, she joined the Abbvie Shanghai R&D Center until its shutdown. In the beginning of 2016, she joined Prof. Dawei Ma’s group in Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences (CAS). She is currently an associate professor with her main interest in the synthesis and development of drug molecules as potential therapeutics of cancer, immune system, or central nervous system diseases.

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Tristan Reekie, Australian National University, Australia

Tristan Reekie obtained his Ph.D. from the Australian National University (ANU), Canberra in organic chemistry focusing on total synthesis and methodology development. He then moved to ETH Zurich as a Postdoctoral Associate in physical organic chemistry before returning to Australia at the University of Sydney where he continued as a postdoctoral fellow. In 2019 Tristan started his independent research career at the ANU. His research interests lie in application based organic synthesis from materials to medicinal and agricultural chemistry. In addition to research, Tristan also has a strong commitment to, and interest in teaching and outreach to the broader community.

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Balaji Rokade, University College Dublin, Ireland

Balaji Vasantrao Rokade was born in Maharashtra, India. After completing his Masters in Organic Chemistry from the Swami Ramanand Teerth Marathwada University, Nanded, he joined the Department of Organic Chemistry, Indian Institute of Science, Bangalore for the Ph.D. programme under the guidance of Prof. K. R. Prabhu in 2009. He received his Ph.D. degree in 2014 and is presently working as a postdoctoral researcher in the group of Prof. Guiry (UCD, Ireland). His current research is focused on design and development of chiral P,N-ligands for asymmetric catalysis.

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Thomas Snaddon, Indiana University, USA

Thomas Snaddon received B.Sc. (Hons.) and M.Phil. degrees from the University of Strathclyde. He was awarded a Ph.D. from the University of Leeds (2008) for research conducted under the mentorship of Prof. Philip J. Kocienski. Postdoctoral appointments with Prof. Alois Fürstner at the Max-Planck-Institut für Kohlenforschung (2008–2010) and Prof. Steven V. Ley at the University of Cambridge (2010–2013) further confirmed his broad interests in synthetic chemistry. He joined the Department of Chemistry at Indiana University in August 2013 where the principal objectives of his research group are (1) the invention of new catalysis-based synthesis methods, and (2) the efficient, concise and scalable syntheses of complex natural substances.

Source list

  • ACS Catalysis
  • Advanced Synthesis & Catalysis
  • Angewandte Chemie International Edition
  • Applied Organometallic Chemistry
  • Asian Journal of Organic Chemistry
  • ChemCatChem
  • Chemical Communications
  • Chemical Science
  • Chemistry – A European Journal
  • Chemistry – An Asian Journal
  • European Journal of Organic Chemistry
  • Green Chemistry
  • Journal of the American Chemical Society
  • Nature
  • Nature Catalysis
  • Nature Chemistry
  • Organic & Biomolecular Chemistry
  • Organic Chemistry Frontiers
  • Organic Letters
  • Organometallics
  • RSC Advances
  • Science
  • Synlett
  • Synthesis
  • Tetrahedron
  • Tetrahedron Letters
  • The Journal of Organic Chemistry

Contact us

Guy Jones: Executive Editor, Data

Sarah Rogers: Content Editor, Synthetic Reaction Updates

Please feel free to contact the Synthetic Reaction Updates team at with any questions or comments.
Version : 2020.0.22.0
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