Synthetic Reaction Updates is a literature alerting service keeping you up to date with recent developments in synthetic organic chemistry. Covering a wide range of primary sources, Synthetic Reaction Updates includes the most important and exciting reactions published in the recent scientific literature. The updates are presented as easily readable reaction schemes and are also searchable by topic and reaction type. Subscribers can set up personalised searches and receive alerts of the latest developments directly via email. Synthetic Reaction Updates replaced Methods in Organic Synthesis and Catalysts & Catalysed Reactions in 2015.


Synthetic Reaction Updates covers a broad range of primary research published in general chemistry and organic chemistry journals. Our Scientific Editors identify the most interesting, novel and relevant reactions, tailoring the selection of articles with synthetic organic chemists in mind. The range of journals included can be seen in the source list.

Information provided by Synthetic Reaction Updates

Each record in the update provides a redrawn reaction scheme with full bibliographic information for the original article. There are also direct links to the publisher’s website where the article can be downloaded. Bibliographic information can be imported into citation management programmes, and the reaction schemes downloaded. Reactions are also classified by reaction type to allow easy browsing.

Email alerts

Personalised searches can be saved to a user’s profile and used to create automatic email alerts that will send details of recently added reactions without having to perform a new search. Readers can also sign up to weekly or monthly updates to browse when they choose.

Scientific Editors

Our Scientific Editors select the most interesting and useful reactions from the recently published scientific literature to include in Synthetic Reaction Updates.

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Gang Deng, AbbVie Shanghai, China

Gang Deng completed his B.S. degree at Shenyang Pharmaceutical University. He worked under the guidance of Prof. Yuan-Chao Li, Shanghai Institute of Materia Medica, on organic methodology and utility studies, receiving his Ph.D. degree in 2007. After a one-year China Postdoctoral Science Foundation postdoctoral stint with Prof. Biao Jiang at the Shanghai Institute of Organic Chemistry on bio-active compound synthesis, he joined Prof. David Lee’s lab at Massachusetts General Hospital in Boston, USA as a postdoctoral researcher working on discovery of novel psychoactive agents. In 2011, he joined Prof. Michael Jung’s group at the University of California, Los Angeles where he developed bioactive small molecules with various activities, including anti-tumor, anti-viral, anti-inflammatory, immunosuppression etc. Since December 2014, he has been working at AbbVie in Shanghai.

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Neil Keddie, University of St Andrews, UK

Neil Keddie is a Senior Postdoctoral Researcher and Teaching Fellow at the University of St Andrews’ School of Chemistry. He currently works in Prof. David O’Hagan’s group researching multi-vicinal fluorinated cyclohexane rings as novel polar motifs as well as teaching undergraduate tutorials and laboratories. Neil studied at the University of St Andrews for his MChem in Chemistry and Medicinal Chemistry, spending a year working for the Dutch pharmaceutical company Organon as an industrial placement student, researching cannabinoid-based short-acting pain relief drugs. After graduating in 2005, he remained at St Andrews to commence his Ph.D. studies with Prof. Stuart Conway (now University of Oxford), working on the synthesis and biological evaluation of D-myo-inositol 1,4,5-trisphosphate receptor ligands. In late 2009 he was awarded his Ph.D. and commenced work with Prof. O’Hagan. In his spare time, Neil is the Secretary of the RSC Tayside Local Section and is the organiser of their ChemBus outreach programme.

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Alastair Lennox, Leibniz Institute for Catalysis, Rostock, Germany

Alastair Lennox conducted his undergraduate studies at the University of Manchester, undertaking a Masters project under the supervision of Dr Ian Watt. He then moved south to Bristol University where he did postgraduate studies with Prof. Guy Lloyd-Jones, investigating the reactivity of organotrifluoroborate salts in Suzuki–Miyaura cross-coupling reactions. He then co-wrote a book before moving to Germany where he is currently undertaking a period of postdoctoral study in the group of Prof. Beller. His research interests include the development of (photo)catalytic transformations in (green) organic chemistry and energy vectors, and the application of physical organic techniques for mechanistic understanding.

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Tristan Reekie, University of Sydney, Australia

Tristan Reekie obtained his Ph.D. from the Australian National University, Canberra in organic chemistry focusing on total synthesis and methodology development. He then moved to the University of Sydney as a postdoctoral fellow in medicinal chemistry, followed by a period as a postdoctoral fellow at ETH Zurich in physical organic chemistry and has recently returned to the University of Sydney. Tristan’s research interests lie in application based organic synthesis from materials to medicinal chemistry. In addition to research, Tristan also has a strong commitment to, and interest in teaching.

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Balaji Rokade, Indian Institute of Science, Bangalore, India

Balaji Vasantrao Rokade was born in Maharashtra, India. After completing his Masters in Organic Chemistry from the Swami Ramanand Teerth Marathwada University, Nanded, he joined the Department of Organic Chemistry, Indian Institute of Science, Bangalore for the Ph.D. programme under the guidance of Prof. K. R. Prabhu in 2009. He received his Ph.D. degree in 2014 and is presently working as a Senior Research Associate in the same department. His current research is focused on developing novel synthetic methods by employing transition metal catalysis and their subsequent application for the synthesis of bioactive natural products.

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Thomas Snaddon, Indiana University, USA

Thomas Snaddon received B.Sc. (Hons.) and M.Phil. degrees from the University of Strathclyde. He was awarded a Ph.D. from the University of Leeds (2008) for research conducted under the mentorship of Prof. Philip J. Kocienski. Postdoctoral appointments with Prof. Alois Fürstner at the Max-Planck-Institut für Kohlenforschung (2008–2010) and Prof. Steven V. Ley at the University of Cambridge (2010–2013) further confirmed his broad interests in synthetic chemistry. He joined the Department of Chemistry at Indiana University in August 2013 where the principal objectives of his research group are (1) the invention of new catalysis-based synthesis methods, and (2) the efficient, concise and scalable syntheses of complex natural substances.

Source list

  • ACS Catalysis
  • ACS Central Science
  • Advanced Synthesis & Catalysis
  • Angewandte Chemie International Edition
  • Applied Organometallic Chemistry
  • Asian Journal of Organic Chemistry
  • Catalysis Science & Technology
  • Catalysis Today
  • ChemCatChem
  • Chemical Communications
  • Chemical Science
  • Chemistry – A European Journal
  • Chemistry – An Asian Journal
  • Dalton Transactions
  • European Journal of Organic Chemistry
  • Green Chemistry
  • Helvetica Chimica Acta
  • Journal of Catalysis
  • Journal of Organometallic Chemistry
  • Journal of the American Chemical Society
  • Nature
  • Nature Chemistry
  • New Journal of Chemistry
  • Organic & Biomolecular Chemistry
  • Organic Chemistry Frontiers
  • Organic Letters
  • Organometallics
  • RSC Advances
  • Science
  • Synlett
  • Synthesis
  • Tetrahedron
  • Tetrahedron Letters
  • Tetrahedron: Asymmetry
  • The Journal of Organic Chemistry

Contact us

Serin Dabb: Executive Editor, Data

Kirsty Muirhead: Data Content Editor, Synthetic Reaction Updates

Please feel free to contact the Synthetic Reaction Updates team at with any questions or comments.
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