RSC Advances
Nanomedicine articles published in the last
6 months
Preparation and characterization of various PVPylated divalent metal-doped ferrite nanoparticles for magnetic hyperthermia
We report the preparation of a panel of biocompatible PVPylated divalent metal-doped MFe2O4 (M= Co, Ni, Zn, Mg, and Sn) ferrites and assess their magneto-thermal abilities for hyperthermia applications. The heating performance directly correlated to their observed magnetic saturation and anisotropy.
RSC Adv., 2024,14, 15664-15679
https://doi.org/10.1039/D4RA01600A
Sono-responsive smart nanoliposomes for precise and rapid hemostasis application
A sono-responsive smart nanoliposome loaded with thrombin (TNL) was developed. The structure of TNL collapses under ultrasonic activation and swiftly releases thrombin from the cavity, thereby achieving a precise and rapid local hemostasis.
RSC Adv., 2024,14, 15491-15498
https://doi.org/10.1039/D3RA08445K
Facile synthesis of an acid-responsive cinnamaldehyde-pendant polycarbonate for enhancing the anticancer efficacy of etoposide via glutathione depletion
A facile synthetic method was developed to prepare a biocompatible acid-responsive polycarbonate containing cinnamaldehyde moieties, a potent GSH-depleting agent, for enhancing the anticancer efficacy of etoposide.
RSC Adv., 2024,14, 15365-15373
https://doi.org/10.1039/D4RA02468K
Manganese-based nanomaterials in diagnostics and chemodynamic therapy of cancers: new development
Manganese-based nanomaterials have seen rapid development in chemodynamic therapy and T1-enhanced MRI over the past five years, holding promising prospects in various combined applications.
RSC Adv., 2024,14, 14722-14741
https://doi.org/10.1039/D4RA01655F
Unleashing the promise of emerging nanomaterials as a sustainable platform to mitigate antimicrobial resistance
The emergence and spread of antibiotic-resistant (AR) bacterial strains and biofilm-associated diseases have heightened concerns about exploring alternative bactericidal methods.
RSC Adv., 2024,14, 13862-13899
https://doi.org/10.1039/D3RA05816F
Recent progress of electrospun nanofibers as burning dressings
Burns are a global public health problem, which brings great challenges to public health and the economy.
RSC Adv., 2024,14, 14374-14391
https://doi.org/10.1039/D4RA01514B
Nanoscale strides: exploring innovative therapies for breast cancer treatment
Nanotechnology revolutionizes breast cancer treatment by improving drug delivery, overcoming barriers, and reducing side effects. This review highlights its potential and superiority over conventional methods, transforming breast cancer management.
RSC Adv., 2024,14, 14017-14040
https://doi.org/10.1039/D4RA02639J
Characterization and antitumor effect of doxorubicin-loaded Fe3O4–Au nanocomposite synthesized by electron beam evaporation for magnetic nanotheranostics
Magnetic nanocomposite prepared by electron beam physical vapor deposition and magneto-mechanochemical synthesis improves antitumor effect and visualization in cancer nanotheranostics.
RSC Adv., 2024,14, 14126-14138
https://doi.org/10.1039/D4RA01777C
Encapsulation of copper phenanthroline within horse spleen apoferritin: characterisation, cytotoxic activity and ability to retain temozolomide
Copper complexes and temozolomide can be co-encapsulated within apoferritin.
RSC Adv., 2024,14, 14008-14016
https://doi.org/10.1039/D3RA07430G
Photostabilities and anti-tumor effects of curcumin and curcumin-loaded polydopamine nanoparticles
In this study, the PDA-Cur NPs has been successfully synthesized and proved to be an anticancer agent with better photostability and increased utilization of curcumin in PDT.
RSC Adv., 2024,14, 13694-13702
https://doi.org/10.1039/D4RA01246A
Nanoparticles incorporated hydrogels for delivery of antimicrobial agents: developments and trends
Nanoparticle-hydrogel systems are versatile biomaterials that possess numerous advantages for biomedical applications. This review focuses on the application of the nanoparticle-hydrogels system for the delivery of antimicrobial agents.
RSC Adv., 2024,14, 13535-13564
https://doi.org/10.1039/D4RA00631C
Self-supplying Cu2+ and H2O2 synergistically enhancing disulfiram-mediated melanoma chemotherapy
Disulfiram (DSF) can target and kill cancer cells by disrupting cellular degradation of extruded proteins and has therefore received particular attention for its tumor chemotherapeutic potential.
RSC Adv., 2024,14, 13180-13189
https://doi.org/10.1039/D4RA01075B
Wet adhesive hydrogels based on niobium carbide for experimental research of oral mucosal impairment
Illustration of the mechanism of NbC/TA–GelMA hydrogel with multifunctional properties for potential application in oral mucosal impairment.
RSC Adv., 2024,14, 12935-12946
https://doi.org/10.1039/D4RA01352B
Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy
HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.
RSC Adv., 2024,14, 12796-12806
https://doi.org/10.1039/D4RA00610K
Current status of controlled onco-therapies based on metal organic frameworks
Most MOFs for controllable cancer treatment act as drug delivery vehicle and/or anti-cancer agent. Molecules with anti-cancer roles such as chemotherapies, gases, peptides or nucleic acids can be loaded into MOFs that decompose in cancer cells or in the TME to release its cargoes.
RSC Adv., 2024,14, 12817-12828
https://doi.org/10.1039/D4RA00375F
Greening the pathways: a comprehensive review of sustainable synthesis strategies for silica nanoparticles and their diverse applications
The graphical abstract describes several synthetic routes of SiNPs and wide range of applications of this nanoparticle.
RSC Adv., 2024,14, 11197-11216
https://doi.org/10.1039/D4RA01047G
Recent advances in photothermal nanomaterials-mediated detection of circulating tumor cells
This review summarizes the application of various photothermal materials in the detection of circulating tumor cells (CTCs), and describes the significance of CTCs detection for early tumor diagnosis and tumor prognosis.
RSC Adv., 2024,14, 10672-10686
https://doi.org/10.1039/D4RA00548A
UV-assisted synthesis of ultra-small GO–Austar for efficient PTT therapeutic architectonic construction
UV-assisted synthesis GO–Austar complexes accomplished synergistic gastric cancer photothermal therapy.
RSC Adv., 2024,14, 10714-10725
https://doi.org/10.1039/D4RA00742E
Cancer cell membrane-coated nanoparticles: a promising anti-tumor bionic platform
This review summarized the function of cancer cell membranes and comprehensively discussed the preparation of cancer cell membrane-coated nanoparticles (CCM-NPs) and their application in anti-tumor therapy. The graphical abstract figure was drawn by Figdraw (https://www.figdraw.com).
RSC Adv., 2024,14, 10608-10637
https://doi.org/10.1039/D4RA01026D
Correction: Ocular biocompatibility evaluation of POSS nanomaterials for biomedical material applications
RSC Adv., 2024,14, 10262-10262
https://doi.org/10.1039/D4RA90030H
Integration of O2-economised tumour-targeted photosensitive magnetic nanomaterials in the diagnosis and therapy of gastric cancer
We constructed a targeted drug platform, ACSN/Fe3O4@MSNs-iRGD, that integrates excellent PDT and MRI.
RSC Adv., 2024,14, 9920-9932
https://doi.org/10.1039/D4RA00497C
Polymer–DNA assembled nanoflower for targeted delivery of dolastatin-derived microtubule inhibitors
Polymer–DNA assembled nanoflower for targeted delivery of dolastatin-derived microtubule inhibitors was developed, and it exhibited increased cellular uptake and enhanced inhibitory effect, especially in multidrug-resistant tumor cell.
RSC Adv., 2024,14, 9602-9608
https://doi.org/10.1039/D3RA08146J
Hetastarch-stabilized polypyrrole with hyperthermia-enhanced release and catalytic activity for synergistic antitumor therapy
Biodegradable HES@CuP-D with good dispersibility has been elaborately fabricated by one-step synthesis using safety-approved hetastarch as a novel stabilizer and CuCl2 as an oxidant for hyperthermia-accelerated DOX release and -enhanced Fenton catalysis against malignant tumors.
RSC Adv., 2024,14, 8445-8453
https://doi.org/10.1039/D3RA08263F
Yolk–shell smart polymer microgels and their hybrids: fundamentals and applications
The classification, synthesis, characterization, properties, and applications of yolk–shell smart microgels and their hybrids have been critically reviewed for further advancement in the area.
RSC Adv., 2024,14, 8409-8433
https://doi.org/10.1039/D4RA00035H
A graft-to strategy of poly(vinylphosphonates) on dopazide-coated gold nanoparticles using in situ catalyst activation
A graft-to-strategy to tether alkyne-terminated polyesters to the surface of dopazide stabilised AuNPs via click chemistry in aqueous conditions in situ.
RSC Adv., 2024,14, 8145-8149
https://doi.org/10.1039/D4RA01116C
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