RSC Advances  

An iodophor-catalyzed 3-sulfenylation of indoles using sulfonyl hydrazides as sulfur source in aqueous phase has been achieved. Iodophor as catalyst and solvent is inexpensive, commercially available and no innocuous to the environment.

Chiral 1-substituted-THβC can be synthesized from L-tryptophan or tryptamine by Pictet–Spengler reaction and chiral auxiliary; also from substituted-DHβC by ATH reaction with chiral catalysts, asymmetric addition reaction, and enzymatic catalysis.

The present work has developed a straightforward, gentle, and effective approach for synthesizing arylamines and 5-substituted-1H-tetrazole derivatives, and among the two tested catalysts, molybdenum trioxide (MoO₃) proved to be highly effective.

FeBr₃-catalysed synthesis of either 3-aroylimidazo[1,2-a]pyridines or 3,3′-(arylmethylene)bis(2-phenylimidazo[1,2-a]pyridines) derivatives from the same starting materials such as 2-arylimidazo[1,2-a]pyridines and aromatic aldehydes were reported.

An efficient, green and convenient protocol for synthesizing amides from secondary alcohols using Fe(NO₃)₃·9H₂O as the mediator, with CH₃CN as the N-source and solvent. This approach was scalable to the gram level.

An efficient Suzuki–Miyuara reaction was developed on unprotected ortho-bromoanilines providing good to excellent yields on a wide variety of substrates. The robustness of the reaction was showcased on gram scale.

Vitamin B₁₂ is a natural and environmentally friendly catalyst.

A key limitation across aminofunctionalizations is incompatibility with substrates bearing medicinally relevant N-heterocycles; in contrast, this aerobic, Cu-catalyzed aminooxygenation engages a diverse range of N-heterocycle-bearing substrates.

Developing new anti-tyrosinase drugs seems crucial for the medical and industrial fields since irregular melanin synthesis is linked to the resurgence of several skin conditions, including melanoma, and the browning of fruits and vegetables.

Development of a telescopic sequence for the last two steps in the CPL302415 synthesis (71.6% total yield). The procedure was generalized into the synthesis of other biologically active PI3Kδ inhibitors based on the pyrazolo[1,5-a]pyrimidine core.

2-Pyrones are valuable structural motifs. This review examines the recent advancements in NHC-catalyzed synthesis of 2-pyrones.

A porous carbon/Fe₃O₄ nanocomposite (PC/Fe₃O₄ nanocomposite) was prepared through the pyrolysis of peanut shells as biowaste with ferrous ferric oxide to give a new magnetically recoverable catalyst and successfully tested on the synthesis of polyhydroquinolines.

The copper-catalyzed strategy employing directing group has proven to be a advantageous approach. In this study, we present the successful application of this strategy to accomplish Heck-type coupling reactions and construct β-lactam skeletons.

Herein, the direct oxidation of furfuryl alcohols and furfurals to the corresponding furoic acids is performed highly efficiently with potassium hydroxide as the base in the presence of a catalytic amount of PNP pincer manganese catalyst in dioxane.

Solvent-free synthesis of Hantzsch 1,4-dihydropyridine catalyzed by montmorillonite K-10 involves oxidation of methyl arenes and in situ-generated ammonia from urea hydrogen peroxide under microwave irradiation.

Wide substrate scope (up to 43 examples); excellent regioselectivity with only para-alkylated product; simple reaction conditions with only TsOH as catalyst, high efficiency in excellent yield; using stable and low toxicity alcohols as alkylate.

No need to heat or additives, applying an economical and benign light source, utilizing an environmentally compatible solvent, aerial conditions, high stability and convenient recyclability of the catalyst are the remarkable highlights of this method.

Water-soluble gold(I)–NHC complexes efficiently catalyze the hydrocarboxylation of terminal and internal alkyne amino acids in aqueous biphasic systems at room temperature, are recyclable for at least 15 cycles, and do not require silver salts.

Ruthenium complexes (RuCat) of triazenide ligands bearing different N-heterocyclic moieties catalyze the hydrogenation of a myriad of substituted nitroarenes under mild reaction conditions.

We present, for the first time, the organo-N-heterocyclic carbene (NHC) catalyzed 1,3-dipolar cycloaddition of 4β-O-propargyl podophyllotoxin (1) with nitrile oxides to afford 4β-isoxazolepodophyllotoxin hybrids (6a–n) in aqueous-organic media.

A mild and general protocol involving amino- and oxyselenation of diverse alkenes for the synthesis of organoselenium compounds has been developed through an environmentally friendly zinc-catalyzed selenofunctionalization reaction.

New series of coumarin derivatives were synthesized as antitubercular agents targeting InhA enzyme with strong binding affinity within the active binding site.

A green and sustainable approach has been developed using a recyclable and reusable LaF₃·Pd nanocatalyst. This catalyst has been applied in the synthesis of biaryls in good to excellent yields via Suzuki coupling in aqueous medium.

Synthesis of quinoid heteroaryls via gold-catalyzed cascade protocols: recent advances and methodologies.

TEMPO-functionalized porous poly(ionic liquid)s prepared via copolymerization exhibits high catalytic efficiency under solvent-metal-free conditions. This study provides a green and sustainable approach for the aerobic oxidation of alcohols.