RSC Advances  

LNPs made with the polyamide PGE have low immunogenicity and outperform PEG-LNPs after chronic administration.

The treatment of diabetic wounds remains a formidable clinical challenge worldwide.

Simvastatin-loaded DPPC/DPPG proliposomes synthesized by spray drying show aerosol dispersion as dry powder inhalers and in vitro sustained delivery.

The treatment and regeneration of bone defects, especially tumor-induced defects, is an issue in clinical practice and remains a major challenge for bone substitute material invention.

The biomedical applications of magnetic nanoparticles (MNPs) have gained increasing attention due to their unique biological, chemical, and magnetic properties such as biocompatibility, chemical stability, and high magnetic susceptibility.

Non-immunogenic RNA nanostructures are functionalized for/with RNAi, mRNA, ribozymes, CRISPR, and small molecule drugs. Immunogenic RNA nanostructures are designed as immunostimulants and cancer vaccine platforms. Created in Biorender.com.

The preparation of glycyrrhetinic acid-modified and redox-sensitive polymeric mixed micelles loaded cantharidin (CTD) which could target to hepatoma carcinoma cell and release CTD rapidly.

The toxicity of 6 small dendrimers has been investigated in three different human cancer cell lines (HeLa, MCF-7, THP-1) and the endothelial skin cell line HMEC-1 in order to evaluate their potential as vehicles for drug delivery.

Recently, molecular hybrids of two or more active pharmacophores have shown promise for designing and synthesizing anticancer drugs.

α-Terpineol loaded, electron beam crosslinked PVA/tapioca pearl starch hydrogel sheets utilised for the healing of a full thickness acid burn wound.

The bottom-up synthesis of gold nanoparticles (AuNPs) using Ocimum sanctum essential oil extracts exhibited excellent antimicrobial and therapeutic potential against MCF 7 breast carcinoma through flow cytometry analysis and DNA damage studies.

Periodontitis is a chronic inflammatory disease primarily caused by dental plaque, which is a significant global public health concern due to its high prevalence and severe impact on oral, and even systemic diseases.

Dimethylamine (DMA) derivatives represent a promising class of compounds with significant potential in the field of medicinal chemistry.

The chia seeds hydrogel (CSH) is a superporous, superabsorbent, haemocompatible, and smart biomaterial exhibiting stimuli-responsive swelling–deswelling behavior and sustained drug release.

A multifunctional nanomedicine has been developed to treat cancer cells by amplifying oxidative stress and integrating bioimaging for therapeutic monitoring.

The design and development of SF-based engineered micro and nano-carriers, with potential enhanced therapeutic performance over traditional delivery methods, could be essential for pharmaceutical research.

Antibiotic (ciprofloxacin)-loaded sodium alginate (SA)–chitosan (CS) nanoparticles (NPs) were incorporated into novel arabinoxylan (AX)–pectin (PC) polymeric films and characterized for application in wound dressing.

BrSPR-20-P1 antimicrobial peptide (P1-AMP) is a novel antimicrobial peptide isolated from Brevibacillus sp. SPR-20 and has been developed as a liposomal in chitosan hydrogel. It has potential to be used as a topical antimicrobial agent.

An amphiphilic polymer-coated GNR platform was studied for chemo- and photothermal combination therapy, promoting controlled drug release, and inducing cellular uptake by deforming the cell membrane under NIR light.

Deep learning-integrated lab-on-a-chip in designing oral [3.1.0] bi and [4.2.0] tricyclic interceptors inhibiting multiple SARS-CoV-2 protomers.

–OH/BNNPs synthesis and release of DOX in a pH dependent manner to induce apoptosis.

Ascorbyl glucoside utilization in the preparation of innovative glucospanlastics loaded itraconazole for topical delivery.

Magnetic protein-coated, drug-loaded nanohybrids have huge potential in future cancer theranostics for real-time monitored drug delivery.

Rapid access to ALC-0315, a crucial component of the formulated Pfizer Covid vaccine, was obtained by employing solid adduct formation and filtration in place of chromatographic separation, allowing for a more scalable synthesis.

The bortezomib (BTZ)-encapsulated metal–phenolic nanoparticles were prepared by the self-assembly of BTZ, tannic acid (TA), and Fe³⁺, which can be used for the intracellular delivery of BTZ.