RSC Advances
Biotechnology articles published in the last
6 months
Antibacterial efficacy of copper-based metal–organic frameworks against Escherichia coli and Lactobacillus
Proposed antibacterial mechanisms of Cu-BTC and Cu-GA. Both MOFs release Cu2+ ions from their framework, facilitating their attachment and internalization on the surface of both E. coli (Gram-negative) and Lactobacillus (Gram-positive) bacteria.
RSC Adv., 2024,14, 15821-15831
https://doi.org/10.1039/D4RA01241K
Chitosan–PVA–PVP/nano-clay composite: a promising tool for controlled drug delivery
Chitosan, polyvinyl alcohol (PVA), and polyvinyl pyrrolidone (PVP) were used to formulate a controlled transdermal drug delivery system for tramadol.
RSC Adv., 2024,14, 15777-15790
https://doi.org/10.1039/D4RA02959C
Preparation and characterization of polydopamine and n-butyl methacrylate copolymer coatings on titanium–nickel alloy stents
PBMA-b-PVP copolymer can improve the adhesion of PBMA homopolymer to TiNi alloys. The PDA coating enhances the corrosion resistance of TiNi alloys. The composite coating demonstrates excellent biocompatibility.
RSC Adv., 2024,14, 15240-15248
https://doi.org/10.1039/D4RA01491J
Lysine-based non-cytotoxic ultrashort self-assembling peptides with antimicrobial activity
Promising results confirmed the antimicrobial activity of L-lysine-based ultrashort dipeptide hydrogels on E. coli and S. aureus bacteria and non-cytotoxic properties on cell viability with human embryonic kidney cell line HEK-293.
RSC Adv., 2024,14, 15120-15128
https://doi.org/10.1039/D3RA08883A
Manganese-based nanomaterials in diagnostics and chemodynamic therapy of cancers: new development
Manganese-based nanomaterials have seen rapid development in chemodynamic therapy and T1-enhanced MRI over the past five years, holding promising prospects in various combined applications.
RSC Adv., 2024,14, 14722-14741
https://doi.org/10.1039/D4RA01655F
Enhanced bone regeneration by osteoinductive and angiogenic zein/whitlockite composite scaffolds loaded with levofloxacin
The zein/WH/LEVO scaffolds have significant effects on promoting bone regeneration, especially for the favorable osteogenic, intensive angiogenic, and alleviated inflammation abilities. The synthesized scaffolds would be used as a suitable material for bone regeneration.
RSC Adv., 2024,14, 14470-14479
https://doi.org/10.1039/D4RA00772G
Unleashing the promise of emerging nanomaterials as a sustainable platform to mitigate antimicrobial resistance
The emergence and spread of antibiotic-resistant (AR) bacterial strains and biofilm-associated diseases have heightened concerns about exploring alternative bactericidal methods.
RSC Adv., 2024,14, 13862-13899
https://doi.org/10.1039/D3RA05816F
Recent progress of electrospun nanofibers as burning dressings
Burns are a global public health problem, which brings great challenges to public health and the economy.
RSC Adv., 2024,14, 14374-14391
https://doi.org/10.1039/D4RA01514B
Nanoscale strides: exploring innovative therapies for breast cancer treatment
Nanotechnology revolutionizes breast cancer treatment by improving drug delivery, overcoming barriers, and reducing side effects. This review highlights its potential and superiority over conventional methods, transforming breast cancer management.
RSC Adv., 2024,14, 14017-14040
https://doi.org/10.1039/D4RA02639J
NIR-responsive magnesium phosphate cement loaded with simvastatin-nanoparticles with biocompatibility and osteogenesis ability
In this article, we reported a specific magnesium phosphate bone cement which showed good physical, chemical properties, and excellent osteogenesis-promoting ability under near-infrared light intervention.
RSC Adv., 2024,14, 13958-13971
https://doi.org/10.1039/D4RA01079E
In vitro encapsulation and expansion of T and CAR-T cells using 3D synthetic thermo-responsive matrices
This work employed a biocompatible and synthetic-based thermo-responsive material with tailored mechanical properties as a potential macro-scale scaffold to support ex vivo T and CAR-T cell encapsulation and culture.
RSC Adv., 2024,14, 13734-13747
https://doi.org/10.1039/D4RA01968G
Engineering peptide-modified alginate-based bioinks with cell-adhesive properties for biofabrication
Alginate-based bioinks used for DoD approaches can be modified with specific peptide-containing components so that incorporated printed cells show significantly higher cell elongation ratios after 7 days (created with https://www.BioRender.com).
RSC Adv., 2024,14, 13769-13786
https://doi.org/10.1039/D3RA08394B
Nanoparticles incorporated hydrogels for delivery of antimicrobial agents: developments and trends
Nanoparticle-hydrogel systems are versatile biomaterials that possess numerous advantages for biomedical applications. This review focuses on the application of the nanoparticle-hydrogels system for the delivery of antimicrobial agents.
RSC Adv., 2024,14, 13535-13564
https://doi.org/10.1039/D4RA00631C
Advancements in application of chitosan and cyclodextrins in biomedicine and pharmaceutics: recent progress and future trends
The global community is faced with numerous health concerns such as cancer, cardiovascular and neurological diseases, diabetes, joint pain, osteoporosis, among others.
RSC Adv., 2024,14, 13384-13412
https://doi.org/10.1039/D4RA01370K
A surface-independent bioglue using photo-crosslinkable benzophenone moiety
The UV-crosslinkable benzophenone (BP) “bio-glue” efficiently crosslinks with various surfaces and biomolecules. The beauty of this bio-glue lies in its simplicity and broad applicability, requiring no sophisticated equipment or reaction conditions.
RSC Adv., 2024,14, 12966-12976
https://doi.org/10.1039/D4RA01866D
Wet adhesive hydrogels based on niobium carbide for experimental research of oral mucosal impairment
Illustration of the mechanism of NbC/TA–GelMA hydrogel with multifunctional properties for potential application in oral mucosal impairment.
RSC Adv., 2024,14, 12935-12946
https://doi.org/10.1039/D4RA01352B
Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy
HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.
RSC Adv., 2024,14, 12796-12806
https://doi.org/10.1039/D4RA00610K
Current status of controlled onco-therapies based on metal organic frameworks
Most MOFs for controllable cancer treatment act as drug delivery vehicle and/or anti-cancer agent. Molecules with anti-cancer roles such as chemotherapies, gases, peptides or nucleic acids can be loaded into MOFs that decompose in cancer cells or in the TME to release its cargoes.
RSC Adv., 2024,14, 12817-12828
https://doi.org/10.1039/D4RA00375F
Introduction to the RSC Advances themed collection on nano and microscale modifications of biomaterials
Andrzej Zieliński and Beata Majkowska-Marzec introduce the RSC Advances themed collection on nano and microscale modifications of biomaterials.
RSC Adv., 2024,14, 11614-11615
https://doi.org/10.1039/D4RA90035A
Innovative wound management: creating dynamic Alg-Mg/SF hydrogels for controlled Mg2+ release in wound healing
Antibacterial hydrogels have gained considerable attention for soft tissue repair, particularly in preventing infections associated with wound healing.
RSC Adv., 2024,14, 10874-10883
https://doi.org/10.1039/D4RA00793J
Preparation of a novel antibacterial magnesium carbonate coating on a titanium surface and its in vitro biocompatibility
We report deposition of a MgCO3 coating on titanium surfaces using a hydrothermal method, followed by hydrogen peroxide treatment. The coating demonstrated antibacterial properties and enhanced osteogenic differentiation of BMSC.
RSC Adv., 2024,14, 10516-10525
https://doi.org/10.1039/D4RA00399C
Dual-core-component multiphasic bioceramic granules with selective-area porous structures facilitating bone tissue regeneration and repair
Ca-phosphate/-silicate ceramic granules have been widely studied because their abilities of biodegradable, bioactive ion release and material degradation; however, it is difficult to synergise time-dependent ion release and highly efficient osteogenesis in vivo.
RSC Adv., 2024,14, 10526-10537
https://doi.org/10.1039/D4RA00911H
Nanogel-based composites for bacterial antibiofilm activity: advances, challenges, and prospects
Nano-based approaches, particularly nanogels, have recently emerged as a potential strategy for combating biofilm-related infections.
RSC Adv., 2024,14, 10546-10559
https://doi.org/10.1039/D4RA00410H
Cancer cell membrane-coated nanoparticles: a promising anti-tumor bionic platform
This review summarized the function of cancer cell membranes and comprehensively discussed the preparation of cancer cell membrane-coated nanoparticles (CCM-NPs) and their application in anti-tumor therapy. The graphical abstract figure was drawn by Figdraw (https://www.figdraw.com).
RSC Adv., 2024,14, 10608-10637
https://doi.org/10.1039/D4RA01026D
Preparation and properties of a 3D printed nHA/PLA bone tissue engineering scaffold loaded with a β-CD–CHX combined dECM hydrogel
Flow chart of nHA/PLA/dECM/β-CD-CHX preparation.
RSC Adv., 2024,14, 9848-9859
https://doi.org/10.1039/D4RA00261J
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