RSC Advances  

Manganese-based nanomaterials have seen rapid development in chemodynamic therapy and T₁-enhanced MRI over the past five years, holding promising prospects in various combined applications.

Nanotechnology revolutionizes breast cancer treatment by improving drug delivery, overcoming barriers, and reducing side effects. This review highlights its potential and superiority over conventional methods, transforming breast cancer management.

Magnetic nanocomposite prepared by electron beam physical vapor deposition and magneto-mechanochemical synthesis improves antitumor effect and visualization in cancer nanotheranostics.

NIR fluorescence-guided PDT offers deep tissue penetration & real-time monitoring, enabling precise tumor treatment with minimal side effects, making it a promising approach for cancer therapy.

A novel hydrocyanine-based turn-on fluorescence probe HCy-Lyso, with excellent lysosome-targeting ability and ˙OH-responsive efficiency, has been applied for monitoring the variation in lysosomal ˙OH levels during ferroptosis.

HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.

This review summarizes the application of various photothermal materials in the detection of circulating tumor cells (CTCs), and describes the significance of CTCs detection for early tumor diagnosis and tumor prognosis.

Cyclodextrin-conjugated low-molecular-weight polyethyleneimine for constructing tumor-targeted macromolecular MRI contrast agent.

We constructed a targeted drug platform, ACSN/Fe₃O₄@MSNs-iRGD, that integrates excellent PDT and MRI.

Applications of chemosensors of phase I metabolizing enzymes.

Detonated and milled nanodiamonds are modified with a fluorescent perylene diimide. The resulting nanodiamonds show enhanced fluorescence, good biocompatibility & uptake by mesenchyml stromal cells, and high fluorescence imaging quality.

FeND loaded with DOX representing a promising theranostic agent for chemo/chemodynamic therapy.

Beta-galactosidase (β-galactosidase), a lysosomal hydrolytic enzyme, plays a critical role in the catalytic hydrolysis of glycosidic bonds, leading to the conversion of lactose into galactose.

This review highlighted recent advancements in the synthesis and biological importance of 1,3-diaryl-2-propen-1-ones. This review summarized the synthesis and biological importance of radiolabelled 1,3-diaryl-2-propen-1-ones as Aβ imaging probes for Alzheimer's disease.

The structure–activity relationship of the synthesized tirbanibulin derivatives was explored; para fluorination on the benzylamine part yielded promising outcomes in potency and pharmacokinetics.