RSC Advances
Drug delivery articles published in the last
6 months
Manganese-based nanomaterials in diagnostics and chemodynamic therapy of cancers: new development
Manganese-based nanomaterials have seen rapid development in chemodynamic therapy and T1-enhanced MRI over the past five years, holding promising prospects in various combined applications.
RSC Adv., 2024,14, 14722-14741
https://doi.org/10.1039/D4RA01655F
Enhanced bone regeneration by osteoinductive and angiogenic zein/whitlockite composite scaffolds loaded with levofloxacin
The zein/WH/LEVO scaffolds have significant effects on promoting bone regeneration, especially for the favorable osteogenic, intensive angiogenic, and alleviated inflammation abilities. The synthesized scaffolds would be used as a suitable material for bone regeneration.
RSC Adv., 2024,14, 14470-14479
https://doi.org/10.1039/D4RA00772G
Unleashing the promise of emerging nanomaterials as a sustainable platform to mitigate antimicrobial resistance
The emergence and spread of antibiotic-resistant (AR) bacterial strains and biofilm-associated diseases have heightened concerns about exploring alternative bactericidal methods.
RSC Adv., 2024,14, 13862-13899
https://doi.org/10.1039/D3RA05816F
Recent progress of electrospun nanofibers as burning dressings
Burns are a global public health problem, which brings great challenges to public health and the economy.
RSC Adv., 2024,14, 14374-14391
https://doi.org/10.1039/D4RA01514B
Nanoscale strides: exploring innovative therapies for breast cancer treatment
Nanotechnology revolutionizes breast cancer treatment by improving drug delivery, overcoming barriers, and reducing side effects. This review highlights its potential and superiority over conventional methods, transforming breast cancer management.
RSC Adv., 2024,14, 14017-14040
https://doi.org/10.1039/D4RA02639J
Characterization and antitumor effect of doxorubicin-loaded Fe3O4–Au nanocomposite synthesized by electron beam evaporation for magnetic nanotheranostics
Magnetic nanocomposite prepared by electron beam physical vapor deposition and magneto-mechanochemical synthesis improves antitumor effect and visualization in cancer nanotheranostics.
RSC Adv., 2024,14, 14126-14138
https://doi.org/10.1039/D4RA01777C
Encapsulation of copper phenanthroline within horse spleen apoferritin: characterisation, cytotoxic activity and ability to retain temozolomide
Copper complexes and temozolomide can be co-encapsulated within apoferritin.
RSC Adv., 2024,14, 14008-14016
https://doi.org/10.1039/D3RA07430G
NIR-responsive magnesium phosphate cement loaded with simvastatin-nanoparticles with biocompatibility and osteogenesis ability
In this article, we reported a specific magnesium phosphate bone cement which showed good physical, chemical properties, and excellent osteogenesis-promoting ability under near-infrared light intervention.
RSC Adv., 2024,14, 13958-13971
https://doi.org/10.1039/D4RA01079E
Photostabilities and anti-tumor effects of curcumin and curcumin-loaded polydopamine nanoparticles
In this study, the PDA-Cur NPs has been successfully synthesized and proved to be an anticancer agent with better photostability and increased utilization of curcumin in PDT.
RSC Adv., 2024,14, 13694-13702
https://doi.org/10.1039/D4RA01246A
Nanoparticles incorporated hydrogels for delivery of antimicrobial agents: developments and trends
Nanoparticle-hydrogel systems are versatile biomaterials that possess numerous advantages for biomedical applications. This review focuses on the application of the nanoparticle-hydrogels system for the delivery of antimicrobial agents.
RSC Adv., 2024,14, 13535-13564
https://doi.org/10.1039/D4RA00631C
Advancements in application of chitosan and cyclodextrins in biomedicine and pharmaceutics: recent progress and future trends
The global community is faced with numerous health concerns such as cancer, cardiovascular and neurological diseases, diabetes, joint pain, osteoporosis, among others.
RSC Adv., 2024,14, 13384-13412
https://doi.org/10.1039/D4RA01370K
Self-supplying Cu2+ and H2O2 synergistically enhancing disulfiram-mediated melanoma chemotherapy
Disulfiram (DSF) can target and kill cancer cells by disrupting cellular degradation of extruded proteins and has therefore received particular attention for its tumor chemotherapeutic potential.
RSC Adv., 2024,14, 13180-13189
https://doi.org/10.1039/D4RA01075B
Wet adhesive hydrogels based on niobium carbide for experimental research of oral mucosal impairment
Illustration of the mechanism of NbC/TA–GelMA hydrogel with multifunctional properties for potential application in oral mucosal impairment.
RSC Adv., 2024,14, 12935-12946
https://doi.org/10.1039/D4RA01352B
Construction of glutathione-responsive paclitaxel prodrug nanoparticles for image-guided targeted delivery and breast cancer therapy
HA-coated redox sensitive visualized nano-prodrug HA/TPE-CS-SS-PTX were exploited in order to highly efficient treatment of cancer and real-time monitoring of drug localization.
RSC Adv., 2024,14, 12796-12806
https://doi.org/10.1039/D4RA00610K
Current status of controlled onco-therapies based on metal organic frameworks
Most MOFs for controllable cancer treatment act as drug delivery vehicle and/or anti-cancer agent. Molecules with anti-cancer roles such as chemotherapies, gases, peptides or nucleic acids can be loaded into MOFs that decompose in cancer cells or in the TME to release its cargoes.
RSC Adv., 2024,14, 12817-12828
https://doi.org/10.1039/D4RA00375F
Skin emitted volatiles analysis for noninvasive diagnosis: the current advances in sample preparation techniques for biomedical application
Analytical technique for monitoring skin-emitted metabolites to diagnose diseases.
RSC Adv., 2024,14, 12009-12020
https://doi.org/10.1039/D4RA01579G
pH-responsive niosome-based nanocarriers of antineoplastic agents
Modified niosomes possessing pH-responsive properties were developed for delivery of antineoplastic agents.
RSC Adv., 2024,14, 11124-11140
https://doi.org/10.1039/D4RA01334D
Immunomodulatory zymosan/ι-carrageenan/ agarose hydrogel for targeting M2 to M1 macrophages (antitumoral)
Zymosan/ι-carrageenan/agarose hydrogel (antitumor) as tumor targeting (M2 to M1 genes) and wound healing material.
RSC Adv., 2024,14, 11694-11705
https://doi.org/10.1039/D3RA06978H
Introduction to the RSC Advances themed collection on nano and microscale modifications of biomaterials
Andrzej Zieliński and Beata Majkowska-Marzec introduce the RSC Advances themed collection on nano and microscale modifications of biomaterials.
RSC Adv., 2024,14, 11614-11615
https://doi.org/10.1039/D4RA90035A
Innovative wound management: creating dynamic Alg-Mg/SF hydrogels for controlled Mg2+ release in wound healing
Antibacterial hydrogels have gained considerable attention for soft tissue repair, particularly in preventing infections associated with wound healing.
RSC Adv., 2024,14, 10874-10883
https://doi.org/10.1039/D4RA00793J
Dual-core-component multiphasic bioceramic granules with selective-area porous structures facilitating bone tissue regeneration and repair
Ca-phosphate/-silicate ceramic granules have been widely studied because their abilities of biodegradable, bioactive ion release and material degradation; however, it is difficult to synergise time-dependent ion release and highly efficient osteogenesis in vivo.
RSC Adv., 2024,14, 10526-10537
https://doi.org/10.1039/D4RA00911H
Nanogel-based composites for bacterial antibiofilm activity: advances, challenges, and prospects
Nano-based approaches, particularly nanogels, have recently emerged as a potential strategy for combating biofilm-related infections.
RSC Adv., 2024,14, 10546-10559
https://doi.org/10.1039/D4RA00410H
Cancer cell membrane-coated nanoparticles: a promising anti-tumor bionic platform
This review summarized the function of cancer cell membranes and comprehensively discussed the preparation of cancer cell membrane-coated nanoparticles (CCM-NPs) and their application in anti-tumor therapy. The graphical abstract figure was drawn by Figdraw (https://www.figdraw.com).
RSC Adv., 2024,14, 10608-10637
https://doi.org/10.1039/D4RA01026D
Preparation and properties of a 3D printed nHA/PLA bone tissue engineering scaffold loaded with a β-CD–CHX combined dECM hydrogel
Flow chart of nHA/PLA/dECM/β-CD-CHX preparation.
RSC Adv., 2024,14, 9848-9859
https://doi.org/10.1039/D4RA00261J
Integration of O2-economised tumour-targeted photosensitive magnetic nanomaterials in the diagnosis and therapy of gastric cancer
We constructed a targeted drug platform, ACSN/Fe3O4@MSNs-iRGD, that integrates excellent PDT and MRI.
RSC Adv., 2024,14, 9920-9932
https://doi.org/10.1039/D4RA00497C
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