RSC Advances
Molecular biology articles published in the last
6 months
Selection, characterization, and biosensing applications of DNA aptamers targeting cyanotoxin BMAA
Scientists have established a connection between environmental exposure to toxins like β-N-methylamino-L-alanine (BMAA) and a heightened risk of neurodegenerative disorders.
RSC Adv., 2024,14, 13787-13800
https://doi.org/10.1039/D4RA02384F
Serendipitous N,S-difunctionalization of triazoles with trifluoromethyl-β-diketones: access to regioisomeric 1-trifluoroacetyl-3-aryl-5-(2-oxo-2-arylethylthio)-1,2,4-triazoles as DNA-groove binders
An expedient construction of DNA groove binder; CF3-containing triazoles via regioselective reaction of trifluoromethyl-β-diketones with 3-mercapto[1,2,4]triazoles.
RSC Adv., 2024,14, 6738-6751
https://doi.org/10.1039/D4RA00083H
Single molecule technique unveils the role of electrostatic interactions in ssDNA–gp32 molecular complex stability
A single-molecule electrophysiology assay was employed using an α-HL nanopore to test the stability of ssDNA and gp32 SSB–protein, in different salt conditions. Low salt and the presence of Zn2+ increases ssDNA–gp32 complex stability.
RSC Adv., 2024,14, 5449-5460
https://doi.org/10.1039/D3RA07746B
Retraction: Novel fatty chain-modified GLP-1R G-protein biased agonist exerts prolonged anti-diabetic effects through targeting receptor binding sites
RSC Adv., 2024,14, 1625-1625
https://doi.org/10.1039/D3RA90124F
Structural modulation of insulin by hydrophobic and hydrophilic molecules
In the bloodstream, insulin interacts with various kinds of molecules, which can alter its structure and modulate its function.
RSC Adv., 2023,13, 34097-34106
https://doi.org/10.1039/D3RA06647A
Achieving high hybridization density at DNA biosensor surfaces using branched spacer and click chemistry
Surface functionalization of glass involving peptide-based branched spacer and click chemistry allows for efficient covalent conjugation of single-strand DNA to achieve high hybridization density tailored for biosensing applications.
RSC Adv., 2023,13, 34003-34011
https://doi.org/10.1039/D3RA04928K
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