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Journal cover: Toxicology Research

Toxicology Research

A new, multi-disciplinary journal covering the best research in both fundamental and applied aspects of toxicology
Impact Factor 3.983 6 Issues per Year
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Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00354G, Paper
Methylmercury (MeHg) is still a major threat for human health and the environment due to its extremely high toxicity that mainly affects the nervous system.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00272A, Paper
Non-protein amino acid beta-N-methylamino-L-alanine (L-BMAA) is a neurotoxin that was associated with the high incidence of Amyotrophic Lateral Sclerosis/Parkinson–Dementia Complex (ALS/PDC) in Guam.
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00420A, Paper
Alcoholism and cigarette smoking are pervasive problems that have been implicated in human health. In this study, independent and combinative toxicities of alcohol and benzo(a)pyrene (BaP) were tested for reproductive...
Xu Wang, Panpan yang, juan Li, Ihsan Awais, Qianying Liu, Guyue Cheng, yanfei Tao, Zhenli Liu and Zonghui Yuan
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00341E, Paper
Quinoxalines (QdNOs) possessing the quinoxaline-1,4-dioxide basic structure were are used for their antibacterial action, although their mechanisms of genotoxicity are not clear. After comparing with the sensitivity of V79 cells...
Prachi Verma, Amit Kunwar, Arai Kenta, Michio Iwaoka and Indira Priyadarsini Kavirayani
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00331H, Paper
A series of the amphiphilic conjugates of dihydroxy selenolane (DHS) and monoamine selenolane (MAS), which we previously reported to inhibit the lipid peroxidation and assist the oxidative protein folding reaction...
Ines Ryma Benmessaoud, Anne-Laure Mahul-Mellier, Endre Horvath, Bohumil Maco, Massimo Spina, Hilal Lashuel and Laszlo Forro
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00303B, Paper
Abstract New technologies launch novel materials; beside their performances in products, their health hazard must be tested. This applies to the lead halide perovskite CH3NH3PbI3 as well, which offers fulgurate...
M. Richter, E. A. Fairhall, S. A. Hoffmann, S. Tröbs, F. Knöspel, P. M. E. Probert, F. Oakley, A. Stroux, M. C. Wright and K. Zeilinger
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00187K, Paper
The rat pancreatic progenitor cell line B-13 is of interest for research on drug metabolism and toxicity since the cells trans-differentiate into functional hepatocyte-like cells (B-13/H) when treated with glucocorticoids.
Tik Shing Cheung, Pui-Man Lau, Haifei Lu, Ho-Pui Ho, Pauline Po Yee Lui and Siu-Kai Kong
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00349K, Paper
Tendon injuries occur commonly in sports and workplace. Tendon-derived stem cells (TDSCs) have great potential for tendon healing because they can differentiate into functional tenocytes. To grow TDSCs properly in...
Yuqing Zhu, Jinquan Li, Zhuo Wu, Yu Lu, Huihui You, Rui Li, Baizhan Li, Xu Yang and Liju Duan
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00259A, Paper
Ozone (O3) in the lower atmosphere is generally derived from various sources of human activity.
Wenchao Xu, Fei Luo, Baofei Sun, Hua Ye, Jun Li, Le Shi, Yi Liu, Xiaolin Lu, Bairu Wang, Qingling Wang, Qizhan Liu and Aihua Zhang
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00225G, Paper
Arsenic is a well established human carcinogen that causes diseases of the lung.
Yubo Li, Haoyue Deng, Liang Ju, Xiuxiu Zhang, Zhenzhu Zhang, Zhen Yang, Lei Wang, Zhiguo Hou and Yanjun Zhang
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00171D, Paper
Currently, drug-induced nephrotoxicity is widespread and seriously affects human health.
Qian Ba, Chao Huang, Yijing Fu, Junyang Li, Jingquan Li, Ruiai Chu, Xudong Jia and Hui Wang
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00378D, Paper
Benzo(a)pyrene (B[a]P) is a common environmental and foodborne pollutant which has been identified as the Group I carcinogen. Although the carcinogenicity of B[a]P has been illustrated, its comprehensive influences on...
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00292C, Paper
Superparamagnetic iron oxide nanoparticles (SPIONs) have been approved for clinical use due to their salient super-paramagnetic properties and low toxicity. Zn2+ doped SPIONs possess significantly higher magnetic susceptibility than that...
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00343A, Paper
Genotoxic carcinogens are present in the human diet, and two important examples are benzo(a)pyrene (BaP) and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). BaP is a polycyclic aromatic hydrocarbon generated by incomplete combustion of organic...
Chieh-Wei Chen, Jing-Hong Huang, Tsung-Ching Lai, Yi-Hua Jan, Michael Hsiao, Chung-Hsuan Chen, Yeukuang Hwu and Ru-shi Liu
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00312A, Paper
Titanium dioxide (TiO2) nanomaterials (NMs) have been widely used to develop commercial products such as sunscreen cosmetics because of their unique optical property to provide complete protection from ultraviolet (UV)...
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C5TX00237K, Paper
In the present study the potential effect of 2-allyl amino 4-methyl sulfanyl butyric acid (AMSB) on glucose metabolism and glycoprotein components in streptozotocin (STZ) induced experimental diabetic rats was carried...
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00211G, Paper
Multi-walled carbon nanotubes (MWCNTs) are beneficial in a wide range of applications in fields such as electronics, optics and nano-medicine, so knowledge concerning their effect on human health is important.
Gözde Kiliç, Carla Costa, Natalia Fernández-Bertólez, Eduardo Pásaro, João Paulo Teixeira, Blanca Laffon and Vanessa Valdiglesias
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00206K, Paper
Iron oxide nanoparticles (ION) have been widely used in biomedical applications, for both diagnosis and therapy, due to their unique magnetic properties.
Wenwen Liu, Changshui Xu, Xi Sun, Haibin Kuang, Xiaodong Kuang, Weiying Zou, Bei Yang, Lei Wu, Fangming Liu, Ting Zou and Dalei Zhang
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C5TX00260E, Paper
Grape seed proanthocyanidin extract (GSPE) is a rich source of proanthocyanidins with multiple biological activities and potential health benefits.
Yu-Sang Li, Chang-Long Leng, Man-Tang Chen, Wei Kevin Zhang, Xiao-Jun Li, He-Bin Tang, Hong-Cai Shang and Li-Hua Zhu
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00317B, Paper
It has been reported that massive levels or/and high frequency exposure of diethylnitrosamine could induce hepatic neoplasm.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00302D, Paper
Sequence-dependent conformational preferences of DNA damaged by aristolochic acid-I.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00164A, Paper
Kavain, an extract from the shrub Piper methysticum, was recently reported to modulate TNF-α expression in both human and mouse cells via regulation of LPS-Induced TNF-Alpha Factor (LITAF).
O. Gladkovskaya, A. Loudon, M. Nosov, Y. K. Gun'ko, G. M. O'Connor and Y. Rochev
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00153F, Paper
Encapsulation of Quantum Dots (QDs) has become an essential factor which regulates particles cytotoxicity and physico-chemical stability.
Rafael Fracasso, Marília Baierle, Gabriela Goëthel, Anelise Barth, Fernando Freitas, Sabrina Nascimento, Louise Altknecht, Virgilio Olsen, Karina Paese, Vinicius Duval da Silva, Iran Castro, Michael Andrades, Nadine Clausell, Adriana Pohlmann, Silvia Guterres and Solange Cristina Garcia
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00207A, Paper
Nanotoxicology aims to study the safety of nanomaterials.
Liye Zhu, Tao Yu, Xiaozhe Qi, Bo Yang, Lei Shi, Haoshu Luo, Xiaoyun He, Kunlun Huang and Wentao Xu
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00104H, Paper
We compared OTA hepatotoxicity in vivo and in vitro. miR-122 regulated the CCNG1/p53 pathway in OTA-induced hepatocyte apoptosis. miR-122 also regulated the Bcl-w/caspase-3 pathway in OTA-induced hepatocyte apoptosis.

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