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Journal cover: Toxicology Research

Toxicology Research

A multidisciplinary journal covering high impact research in fundamental, translational and applied areas of toxicology; the official journal of The British Toxicology Society and The Chinese Society of Toxicology
Impact Factor 3.983 6 Issues per Year
 
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Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00056H, Review Article
Quantum dots (QDs), a semiconductor nanomaterials with tiny light-emitting particles, act as important alternatives of conventional fluorescent dyes for biomedical imaging. With the increased tendency of QDs applications, concerns about...
 
Qian Sun, Ming Ying, Quan Ma, Zhijun Huang, Liangyu Zou, Jianjun Liu, Zhixiong ZHuang and Xifei Yang
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C5TX00456J, Paper
This is an Accepted Manuscript, which has been through the RSC Publishing peer review process and has been accepted for publication. Accepted manuscripts are published online shortly after acceptance. This version of the article will be replaced by the fully edited, formatted and proof read Advance Article as soon as this is available.
 
Xingyu Liu, Jie Zhang, Chen Zhang, Bicheng Yang, Limeng Wang and Jun Zhou
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00016A, Paper
NNK is considered to be the most carcinogenic compounds of the four TSNAs and necessary to be metabolically activated to exert its carcinogenic effect to human. For the simultaneous intake...
 
Ming-Hui Li, Hua-Dong Xu, Yan Liu, Ting Chen, Lei Jiang, Yong-Hong Fu and Jun-Song Wang
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00011H, Paper
Glyphosate disturbed the metabolomic profiles of goldfish, with regard to metabolic pathways that were related with its toxicity.
 
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00026F, Paper
UVB exposure enhances the internalization of ZnO-NPs and caused changes in surface morphology of SKH-1 mouse skin.
 
Harriet Gaskell, Parveen Sharma, Helen E Colley, Craig Murdoch, Dominic P Williams and Steven D Webb
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00101G, Paper
More predictive in vitro liver models are a critical requirement for preclinical screening of compounds demonstrating hepatotoxic liability. 3D liver spheroids have been shown to have an enhanced functional lifespan...
 
Sandhra M. Carvalho, Herman S. Mansur, Fábio P. Ramanery, Alexandra A. P. Mansur, Zelia I. P. Lobato and Maria F. Leite
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00039H, Communication
Carboxymethyl chitosan-Bi2S3 quantum dots nanoconjugates : from polysaccharides to cytocompatible fluorescent biohybrids.
 
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00083E, Paper
The figure shows the prediction performance of (a) DTF-QSAR and (b) DTB-QSAR models for pLOAEL (rat) in training and test data.
 
Yangsheng Lin, Xi Li, Li Zhang, Yongqiang Zhang, Huili Zhu, Ying Zhang, Zhuge Xi and Danfeng Yang
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00015K, Paper
Concern has been growing over the potential hazard of nanoparticles to human health because of increasing ambient particulate air pollution. Much research has been performed on the toxicology of nanoparticles...
 
Valeria Bellisario, Giulio Mengozzi, Elena Grignani, Massimiliano Bugiani, Anna Sapino, Gianni Bussolati and Roberto Bono
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00068A, Paper
Purpose: Nurses are exposed to Formaldehyde when managing surgical samples to be later transferred to Histopathology. We evaluated conditions favouring the risk of exposure to this toxic reagent and the...
 
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00071A, Paper
Recently derived in silico structural descriptors for both ILs cations and anions allowed the development of a QSPR model correlating ionic liquids structures to Vibrio fischeri toxicity using the partial...
 
Tian-Guang Zhang, Yi-Mei Wang, Jun Zhao, Ming-Yu Xia, Shuang-Qing Peng and Takashi Ikejima
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00470E, Paper
Isoniazid (INH) activated autophagy and the p38 signaling pathway against apoptosis in human hepatocarcinoma HepG2 cells.
 
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00440C, Paper
Diallyl trisulfide (DATS) has been verified to ameliorate hepatotoxicity induced by many drugs, but the protective actions of isoniazid (INH) and rifampicin (RFP) have not been reported.
 
Ruilong Yang, Qi Rui, Ling Kong, Nanjing Zhang, Yu Li, Xinyu Wang, Jing Tao, Peiyao Tian, Yan Ma, Jianrong Wei, Guojun Li and Dayong Wang
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00022C, Paper
Beijing, capital of China, is frequently facing upon heavy air pollution. In this study, we performed the toxicological assessment of outdoor PM2.5 collected from Beijing during Spring Festival using in...
 
Hejing Hu, Jing Wu, Qiuling Li, Collins Asweto, Lin Feng, Xiaozhe Yang, Fengkui Duan, Junchao Duan and Zhiwei Sun
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00351B, Paper
Fine particulate matter induces vascular endothelial activation via IL-6 dependent JAK1/STAT3 signaling pathway.
 
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00496A, Paper
In recent years, pancreatic pathologies have become common problems and their etiology and pathogenesis are generally unknown.
 
Yan Wang, Di Liang, Zhonghui Zhu, Xiaoli Li, Guoliang An, Piye Niu, Li Chen and Lin Tian
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00471C, Paper
Silica induced EMT and decreased the expression of BMP-7 in vivo and in vitro, while exogenous BMP-7 promoted MET and inhibited silica-induced EMT associated with inhibition of the p38 MAPK/transcription factor (TF) signaling pathway in RLE-6TN cells.
 
Fei Zhao, Jing Wang, Yanjun Fang, Jia Ding, Honglian Yang, Li Li, Zhuge Xi and Haixuan Qiao
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00374A, Paper
This study focused on the effects of TDCIPP on thyroid function and hormone homeostasis in mammals. Our results certified that TDCIPP induces slight thyroid follicular hyperplasia, disturbs the normal bioprocess on TH synthesis, biotransformation and hepatic detoxification of pubertal female SD rats, causing thyroid function disorder.
 
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00004E, Paper
Our data represent the first demonstration that oxy-PAHs can be potent inhibitors of CYP1 expression and function.
 
Katarzyna Wojdyla, Krzysztof Wrzesinski, James Williamson, Stephen J. Fey and Adelina Rogowska-Wrzesinska
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00469A, Paper
Acetaminophen (APAP) is possibly the most widely used medication globally and yet little is known of its molecular effects at therapeutic doses.
 
Tapan Dey, Prachurjya Dutta, Prasenjit Manna, Jatin Kalita, Hari Prasanna Deka Boruah, Alak Kumar Buragohain, Balagopalan Unni, Dibyajyoti Ozah, Mihir Kumar Goswami and Ratan Kumar Kotokey
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00477B, Paper
Cigarette smoke has always been considered as a risk factor for chronic obstructive pulmonary diseases (COPD).
 
Chad H. G. Allen, Alexios Koutsoukas, Isidro Cortés-Ciriano, Daniel S. Murrell, Thérèse E. Malliavin, Robert C. Glen and Andreas Bender
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00406C, Paper
Using three descriptor domains – encoding complementary bioactivity data – enhances the predictive power, applicability, and interpretability of rat acute-toxicity classifiers.
 
Roberto Bono, Armelle Munnia, Valeria Romanazzi, Valeria Bellisario, Filippo Cellai and Marco E. M. Peluso
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00478K, Paper
The generation of M1dG adducts can constitute an additional molecular mechanism for formaldehyde-induced nasal carcinogenesis.
 
Yongbo Yu, Junchao Duan, Yang Yu, Yang Li, Yang Zou, Yumei Yang, Lizhen Jiang, Qiuling Li and Zhiwei Sun
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00465A, Paper
The present study investigated both autophagy and apoptosis in ICR mice and Human hepatocellular carcinoma cells (HepG2), and then explored the interactive mechanism between these two distinct cell death modalities in HepG2 cells.
 
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00424A, Review Article
Recent updates on various molecular and pathophysiological aspects of the zinc transporter ZIP8 (SLC39A8).
 

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