Journal cover: Toxicology Research

Toxicology Research

A new, multi-disciplinary journal covering the best research in both fundamental and applied aspects of toxicology
Impact Factor 3.273 (Partial) 6 Issues per Year
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Daniel José Barbosa, João Paulo Capela, Maria de Lourdes Bastos and Flix Dias Carvalho
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00043A, Review Article
The nervous system is a highly complex system, including many cell types with multiple functions, with an intricate anatomy and unique structural and functional characteristics, in which the study of...
Roger Godschalk, Nicole Verhofstad, Marcha Christina Theodora Verheijen, Carole Lyn Yauk, Joost Linschooten, Harry van Steeg, Conny van Oostrom, Jan van Benthem and Frederik Jan van Schooten
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00114A, Paper
Paternal exposure to the environmental contaminant benzo[a]pyrene (B[a]P) may pose a genetic risk to future generations, because B[a]P or its metabolites reach the testis and cause DNA damage and global...
Huanliang Liu, Honglian Yang, Bencheng Lin, Wei Zhang, Lei Tian, Huashan Zhang and Zhuge Xi
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00154K, Paper
Abstract Zinc oxide, titanium dioxide and silver nanoparticles are used as sterilization materials to enhance the performance of disinfectants. Here, the toxicological effects on the liver, spleen, thymus gland, immune...
Isaac A. Adedara, Denis B. Rosemberg, Diogo O. Souza, Jean P. Kamdem, Ebenezer O. Farombi, Michael Aschner and Joao B. T. Rocha
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00231H, Paper
Methylmercury (MeHg) is well-known for its neurodevelopmental effects both in animals and in humans.
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00210E, Paper
Cerium dioxide nanoparticles have many applications including use as a diesel fuel additive. Concerns over the increased use of engineered nanoparticles and the potential risks to the public have led...
Mahsa Karbaschi, Salvador Macip, Mark D Evans, Vilas Mistry, Hussein H K Abbas, Marcus S Cooke, George J Delinassios and Anthony Young
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00197D, Paper
Classically, the nucleotide excision repair (NER) of cyclobutane pyrimidine dimers (CPD) is a lengthy process (t1/2 > 48 h). Using the T4 endonuclease V-modified comet assay, we uniquely found a...
Begum Yurdakok, Ayhan Filazi, Husamettin Ekici, Tolga Hasan Celik and Ufuk Tansel Sireli
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C5TX90004B, Correction
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00141A, Paper
The comprehensive identification and mechanistic analysis of reproductive toxicants constitutes one of the major hurdles in the toxicological assessment of chemicals originating from the large number of chemicals to be...
Abdullah Al-Ali, Neenu Singh, Bella Manshian, Tom Wilkinson, John Wills, Gareth J. S. Jenkins and Shareen H. Doak
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00175C, Paper
Quantum dots (QD) with varying surface chemistry can have an impact on cellular uptake and a range of indicators for cell perturbation.
Katarzyna M. Bloch, Noreen Yaqoob, Sikander Sharma, Andrew Evans, Lydia Aschauer, Robert Radford, Paul Jennings, Michael P. Ryan, Joost H. M. van Delft and Edward A. Lock
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00113C, Paper
Monuron (1,1-dimethyl-3-(4-chlorophenyl)urea) is a widely used herbicide in developing countries although concerns have been raised about its toxicity and carcinogenicity.
Wu Chun-qi, Li Yu-feng, Zheng Zhi-bing, Dong Yan-sheng, Yuan Ben-li, Li Song, Liao Ming-yang and Wang Quan-jun
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00109E, Paper
LPS-induced inflammatory response could be used to establish screening models for ILT and provides a new way to reduce liver toxicity of Z24.
Sílvio Terra Stefanello, Edovando José Flores da Rosa, Fernando Dobrachinski, Guilherme Pires Amaral, Nélson Rodrigues de Carvalho, Sônia Cristina Almeida da Luz, Caroline Raquel Bender, Ricardo S. Schwab, Luciano Dornelles and Félix Alexandre Antunes Soares
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00166D, Paper
Hepatic encephalopathy is a common complication of severe acute hepatic failure and has been associated with high short-term mortality rates.
Igor Pujalté, Isabelle Passagne, Richard Daculsi, Caroline de Portal, Céline Ohayon-Courtès and Béatrice L'Azou
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00184B, Paper
Many uncertainties remain regarding the potential toxic effect of nanoparticles.
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00207E, Paper
Both translocation into targeted neurons and developmental and functional alterations in targeted neurons contribute to CdTe QDs neurotoxicity.
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00147H, Paper
The BCRP (ABCG2) transporter is responsible for the efflux of chemicals from the placenta to the maternal circulation.
Francisco Assis Bezerra da Cunha, Gabriel Luz Wallau, Antonio Ivanildo Pinho, Mauro Eugenio Medina Nunes, Nadghia Figueiredo Leite, Saulo Relison Tintino, Galberto Martins da Costa, Margareth Linde Athayde, Aline Augusti Boligon, Henrique Douglas Melo Coutinho, Antonio Batista Pereira, Thais Posser and Jeferson Luis Franco
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00162A, Paper
Eugenia uniflora L. (Myrtaceae family), also known as “pitanga”, is a tree species widely used in popular medicine.
Ruei-Yue Liang, Hsin-Fang Tu, Xiaotong Tan, Yu-Shan Yeh, Pin Ju Chueh and Show-Mei Chuang
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00181H, Paper
A unique four-gene signature for AuNP exposure was identified using the cDNA microarray and evaluated by qPCR and biological assays in mammalian cell lines.
Massimiliano G. Bianchi, Manfredi Allegri, Anna L. Costa, Magda Blosi, Davide Gardini, Camilla Del Pivo, Adriele Prina-Mello, Luisana Di Cristo, Ovidio Bussolati and Enrico Bergamaschi
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00193A, Paper
TiO2 nanoparticles enhance LPS-dependent NO production and cytokine secretion through a mechanism that involves TLR4-mediated p38-signalling and requires phagocytosis.
A. Daoust, E. L. Barbier, S. Bohic, V. Stupar, S. Maunoir-Regimbal and F. Fauvelle
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00135D, Paper
The HRMAS spectrum revealed an important impact of Mn 500 nmol on the hippocampal metabolism, not observed with Mn 8 nmol.
Na Sun, Liudmila Tekutyeva, Shiping Wang, Qiankun Pu, Cui Zhou, Jing Wang and Huilian Che
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00211C, Paper
Assessment of the allergenic potential of food proteins, including novel proteins, is an important issue. However, the current weight-of-evidence approach cannot provide a direct evaluation of inherent allergenic potential of...
lu sun, Chen Zhang, Yingjie Chen, Xiao Li, Shulin Zhuang, Weihua Li, Guixia Liu, Philip W. Lee and Yun Tang
Toxicol. Res., 2015, Accepted Manuscript
DOI: 10.1039/C4TX00174E, Paper
Aquatic toxicity is an important endpoint in evaluation of chemical adverse effects on ecosystems. In this study, in silico models were developed for prediction of chemical aquatic toxicity on different...
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00156G, Paper
Mitochondrial dysfunction and oxidative damage may be the initial events of copper nanoparticle (CuNP)-induced hepato and nephrotoxicity.
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00131A, Paper
Insulin signaling pathway may act as an important molecular basis for the toxicity of traffic-related PM2.5 in Caenorhabditis elegans, a non-mammalian toxicological model.
Zhi-Hua Liu, Ye Yang, Meng-Meng Ge, Li Xu, Yuqing Tang, Fan Hu, Yi Xu and Hui-Li Wang
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00093E, Paper
Based on Wnt signaling pathway, this study aims to further mechanistically understand memory alteration after BPA exposure.
Mingyu Su, Lei Sheng, Xiaoyang Zhao, Ling Wang, Xiaohong Yu, Jie Hong, Bingqing Xu, Dong Liu, Hao Jiang, Xiao Ze, Yunting Zhu, Yi Long, Junling Zhou, Jingwen Cui, Kai Li, Yuguan Ze and Fashui Hong
Toxicol. Res., 2015, Advance Article
DOI: 10.1039/C4TX00106K, Paper
Titanium dioxide nanoparticles (TiO2 NPs) have been widely used in industry and daily life; their potential neurotoxic effects are of great concern.

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