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Journal cover: Toxicology Research

Toxicology Research

A multidisciplinary journal covering high impact research in fundamental, translational and applied areas of toxicology; the official journal of The British Toxicology Society and The Chinese Society of Toxicology
Impact Factor 3.983 6 Issues per Year
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Eugenie Nepovimova, Jan Korabecny, Rafael Dolezal, Thuy Duong Nguyen, Daniel Jun, Ondrej Soukup, Marketa Pasdiorova, Petr Jost, Lubica Muckova, David Malinak, Lukas Gorecki, Kamil Musilek and Kamil Kuca
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00130K, Communication
Chemical warfare agents constitute an increasing threat to both military and civilian population. Therefore, effective prophylactic approach is urgently needed. Herein, we present novel hybrid compound able not only to...
Zhengbao Zhang, Liping Chen, Xiumei Xing, Daochuan Li, Chen Gao, Zhini He, Jie Li, Xiaonian Zhu, Xinhua Xiao, Shan Wang, Fangping Wang, Zefang Ren, Yongmei Xiao, Shyamali Chandrika Dharmage, Guang-Hui Dong, Yuxin Zheng and Wen Chen
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00112B, Paper
To investigate whether polycyclic aromatic hydrocarbons (PAHs) exposure is associated with specific histone modifications and whether DNA damage triggers epigenetic alterations, we recruited 190 male workers with occupational exposure to...
Shanting Liao, Pei Li, Junsong Wang, Qian Zhang, Dingqiao Xu, Minghua Yang and Lingyi Kong
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00082G, Paper
LPS disturbed the metabolomic profiles in the serum, livers and kidneys of mice, and baicalin ameliorated these disturbances.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00024J, Paper
The effect of mixtures of PAHs and heavy metal/loid(s) on the Nrf2 antioxidant pathway in HepG2-ARE cells was determined as an indicator of the oxidative stress response.
Xiaolin Lu, Yang Liu, Fei Luo, Aihua Zhang, Xinlu Liu, Lu Lu, Le Shi, Jun Li, Junchao Xue, Hui Xu, Weimin Fan and Qizhan Liu
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00041J, Paper
MicroRNAs are involved in the epithelial–mesenchymal transition (EMT) and malignant transformation of cells.
Pinpin Lin, Yi-Rong Chen, Chao-Yu Chen, Ya-Ting Chang , Jhih-Sheng Chen , Ming-Hsien Tsai , Cheng-Chin Kuo and Hui-Ling Lee
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00010J, Paper
Studies suggest that gene mutation and carcinogens exposure contribute to lung tumorigenesis including mutation of epidermal growth factor receptor (EGFR) and exposure to benzo[a]pyrene (BaP). However, the interaction between EGFR...
Marco Pelin, Chiara Florio, Cristina Ponti, Marianna Lucafò, Davide Gibellini, A. Tubaro and Silvio Sosa
Toxicol. Res., 2016, Accepted Manuscript
DOI: 10.1039/C6TX00084C, Paper
Palytoxin (PLTX) is one of the most harmful marine toxins known so far. Although the ingestion of contaminated seafood is the most dangerous exposure route for humans, cutaneous and inhalational...
Qian Sun, Ming Ying, Quan Ma, Zhijun Huang, Liangyu Zou, Jianjun Liu, Zhixiong Zhuang and Xifei Yang
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00456J, Paper
Recent studies suggest that copper exposure, even at very low levels, can produce significant toxic effects on the brains of mice.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00056H, Review Article
We summarize recent progress on the biological effects, translocation, and metabolism of QDs in the in vivo assay system of C. elegans.
Xingyu Liu, Jie Zhang, Chen Zhang, Bicheng Yang, Limeng Wang and Jun Zhou
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00016A, Paper
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is considered to be the most carcinogenic of the four tobacco-specific nitrosamines (TSNAs) and it needs to be metabolically activated to exert its carcinogenic effect on humans.
Yangsheng Lin, Xi Li, Li Zhang, Yongqiang Zhang, Huili Zhu, Ying Zhang, Zhuge Xi and Danfeng Yang
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00015K, Paper
Concern has been growing over the potential hazard of nanoparticles to human health because of increasing ambient particulate air pollution.
Valeria Bellisario, Giulio Mengozzi, Elena Grignani, Massimiliano Bugiani, Anna Sapino, Gianni Bussolati and Roberto Bono
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00068A, Paper
Nurses are exposed to formaldehyde when managing surgical samples that are to be later transferred to histopathology.
Gözde Kiliç, Carla Costa, Natalia Fernández-Bertólez, Eduardo Pásaro, João Paulo Teixeira, Blanca Laffon and Vanessa Valdiglesias
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX90013E, Correction
Harriet Gaskell, Parveen Sharma, Helen E. Colley, Craig Murdoch, Dominic P. Williams and Steven D. Webb
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00101G, Paper
We have developed a method for creating C3A liver spheroids and demonstrated cellular polarisation, zonation as well as increased liver-specific functionality and more predictive toxicological response compared to standard 2D liver models.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00071A, Paper
In silico structural descriptors for both cation and anion counterparts of ILs allow the prediction of Vibrio fischeri toxicity by means of a simple three parameter equation.
Ruilong Yang, Qi Rui, Ling Kong, Nan Zhang, Yu Li, Xinyu Wang, Jing Tao, Peiyao Tian, Yan Ma, Jianrong Wei, Guojun Li and Dayong Wang
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00022C, Paper
mtl-1 and mtl-2 encoded metallothioneins act downstream of insulin signaling to regulate toxicity of outdoor PM2.5 during Spring Festival in Beijing.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00054A, Paper
Novel gold–zinc telluride (Au–ZnTe) core–shell nanoparticles were synthesized to support surface modifications for enhanced drug delivery in cancer therapeutics.
Ming-Hui Li, Hua-Dong Xu, Yan Liu, Ting Chen, Lei Jiang, Yong-Hong Fu and Jun-Song Wang
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00011H, Paper
Glyphosate disturbed the metabolomic profiles of goldfish, with regard to metabolic pathways that were related with its toxicity.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00026F, Paper
UVB exposure enhances the internalization of ZnO-NPs and caused changes in surface morphology of SKH-1 mouse skin.
Sandhra M. Carvalho, Herman S. Mansur, Fábio P. Ramanery, Alexandra A. P. Mansur, Zelia I. P. Lobato and Maria F. Leite
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00039H, Communication
Carboxymethyl chitosan-Bi2S3 quantum dots nanoconjugates : from polysaccharides to cytocompatible fluorescent biohybrids.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C6TX00083E, Paper
The figure shows the prediction performance of (a) DTF-QSAR and (b) DTB-QSAR models for pLOAEL (rat) in training and test data.
Toxicol. Res., 2016, Advance Article
DOI: 10.1039/C5TX00424A, Review Article
Recent updates on various molecular and pathophysiological aspects of the zinc transporter ZIP8 (SLC39A8).

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