Journal cover: Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry

The international home of synthetic, physical and biomolecular organic chemistry.
Impact Factor 3.487 48 Issues per Year Indexed in MEDLINE
  • All Recent Articles
  • |
  • Advance Articles
  • |
  • Accepted Manuscripts
arrow_left Prev Pg 1 of 7 Next arrow_right
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01474J, Paper
We used a microflow system to study the nucleophilic cyclopropanation of hexa-1,5-diene-3,4-diones with bis(iodozincio)methane. This reaction afforded the zinc alkoxides of cis-dialkenylcylopropane-1,2-diols stereoselectively. The subsequent oxy-Cope rearrangement of cis-dialkenylcylopropane-1,2-diols afforded...
Fengtian Wu, Jie Zhang, Qianbing Wei, Ping Liu, Jianwei Xie, Haojie Jiang and Bin Dai
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02068E, Paper
A wide range of 2-substituted benzoxazoles could be efficiently synthesized from the N-(2-iodo-/bromo-phenyl)benzamides, even less reactive N-(2-chlorophenyl)benzamides via Cu-catalysed intramolecular coupling cyclization using methyl 2-methoxybenzoate as the ligand under mild...
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02042A, Paper
Maculalactone A (1) constitutes a promising antifouling agent inhibiting the formation of biofilms in marine and freshwater systems. In this study, we developed a new route based on a late-stage...
Juan J. Vaquero, Rosa Suarez, Pedro Bosch, Dr. David Sucunza, Ana M. Cuadro, Alberto Domingo and Francisco Mendicuti
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01465K, Paper
A library of azonia aromatic cations has been studied in order to gain an insight into the role of the size, shape and charge distribution on the fluorescence, DNA interactions...
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01320D, Paper
A catalytic decarboxylative annulation has been developed for the regioselective synthesis of trisubstituted furans by the cycloaddition of ketones with α,β-unsaturated carboxylic acids under ambient air. A library of furan...
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01519C, Paper
A Brønsted acid promoted synthesis of 2-amino-5-aroylmethylthiazoles has been developed via C–C bond cleavage reaction. The products can be easily transformed into PLTP and CETP inhibitor, and are useful precursors to access novel biheterocycles.
jessy aziz, SAMIR MESSAOUDI, Mouad Alami and abdallah hamze
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01727G, Review Article
Sulfinic acids and their salts have recently emerged as versatile coupling partners to efficiently access a wide variety of hetero- and carbocyclic compounds, under relatively mild conditions. Their growing importance...
Lorena Tizón, María Maneiro, Antonio Peon, José Otero, Emilio Lence, Sergio Poza, Mark J. van Raaij, Paul Thompson, Alastair R. Hawkins and Concepcion Gonzalez-Bello
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01782J, Paper
The irreversible inhibition of type I dehydroquinase (DHQ1), the third enzyme of the shikimic acid pathway, has been investigated by structural, biochemical and computational studies. Two epoxides, which are mimetics...
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02023E, Paper
Ergothioneine along with mycothiol, are low molecular mass redox protective thiols present in Actinomycetes, in particular mycobacteria. We report the improved chemical synthesis of ergothioneine (ESH) and biosynthetic pathway intermediates...
Zhicheng Dai, Yongfei Chen, Mao Zhang, Shengkun Li, Tingting Yang, Li Shen, Jianxin Wang, Shao-Song Qian, Hai-Liang Zhu and Yonghao Ye
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01758G, Paper
A series of 1,2,3-triazole phenylhydrazone were designed and synthesized as antifungal agents. Their structures were determined based on 1H-NMR spectroscopy, MS, elemental analysis and X-ray single-crystal diffraction. The antifungal activities...
J C Anderson, Ian B Campbell, Sebastien Campos, Jonathan Shannon and D A Tocher
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01793E, Paper
A conjugate addition nitro-Mannich reaction followed by nitro reduction and intramolecular N-arylation gives diastereomerically pure substituted 1,2-diamine containing indolines. Placing the N-arylation cyclisation handle on the imine precursor derived from...
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01663G, Review Article
Highly functionalized fullerenes can be efficiently constructed by various techniques.
Hong-Hao Zhang, Xiao-Xue Sun, Jing Liang, Yue-Ming Wang, Chang-Chun Zhao and Feng Shi
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01741B, Paper
The first catalytic asymmetric Povarov reaction of isatin-derived 2-azadienes with 3-vinylindoles has been established to construct a spiro[indolin-3,2′-quinoline] framework bearing an indole moiety.
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01580K, Paper
An efficient and practical synthetic approach giving access to 2H-pyrrolo[3,4-c]quinolin-4(5H)-one/2H-pyrrolo[3,4-c]quinoline derivatives via a one pot van Leusen reaction and cyclization under basic conditions.
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01979B, Communication
A palladium-catalyzed cascade reaction that involves π-allylic palladium species generated from carbene migratory insertion leads to the formation of 2H-chromenes.
Yong-Ming Sun, Nana Xin, Zhong-Yuan Xu, Li-Juan Liu, Fan-Jie Meng, He Zhang, Bao-Ci Fu, Qiu-Ju Liang, Hong-Xing Zheng, Li-Jun Sun, Chang-Qiu Zhao and Li-Biao Han
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01574F, Paper
A stability-controlled diastereoselective addition of a chiral P–H species to ketones afforded P,C-stereogenic α-hydroxyphosphinates in excellent yields and dr.
Guohua Chen, Qiang Yin, jian yin, Xiangying Gu, Xiao Liu, Qidong You, Yue-Lei Chen, Bing Xiong and Jingkang Shen
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01807A, Communication
For the first time, we demonstrated that the Tf2O mediated direct dehydrative glycosylation was possible simply with strained olefins, and other typical bases were inhibitors of this reaction. We optimized...
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB02021A, Paper
In a screening program of natural compounds from fungi, the known cyclopentanoid sesquiterpene (–)-cyclonerodiol was identified as a specific inhibitor of the IL-4 induced STAT6 signaling pathway (IC50 = 9.7...
Angel L. Fuentes de Arriba, Ángel Gómez Herrero, Omayra Hernandez Rubio, Laura Marcos Monleon, Luis Simon, Victoria Alcázar, Francisca Sanz and Joaquin Rodriguez Moran
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01954G, Paper
A new chiral benzofuran receptor has been synthesized and its properties in the association of amino acid derivatives have been studied. X-ray structures were obtained and these corroborate the presence...
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01860E, Paper
Ethynyl pyrene and ethynyl nile red as modifications at the 5-position of 2’-deoxuridines self-assemble non-covalently and specifically along oligo-2’-deoxyadenosines as templates. Oligo-2’-deoxyadenosines of the lengths (dA)10 - (dA)20 are able...
Org. Biomol. Chem., 2014, Accepted Manuscript
DOI: 10.1039/C4OB01878H, Paper
A series of aryl-palladium-NHC compounds were prepared according to the reported methods and their catalytic activity in the carbonylation of aryl iodides to synthesize α-keto amides and alkynones were examined....
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01596G, Communication
Rh(III) complexes catalyzed the ortho C–H alkynylation of azomethine imine, which acts as a masked aldehyde group.
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01385A, Paper
The reactivity of aldehydes and ketones in asymmetric organo-SOMO reactions with enol silanes was explored. The best results were obtained with 3-phenylpropanal and tetralone-derived silyl enol ether and silyl ketene thioacetal.
Supravat Samanta, Venkatanarayana Pappula, Milan Dinda and Subbarayappa Adimurthy
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01524J, Paper
Oxidative esterification of benzylic alcohols with catalytic HBr in aqueous medium under mild conditions is reported with a broad substrate scope including selective mono-esterification of ethylene glycol and glycerol.
Tony K. M. Shing, Anthony W. H. Wong, Huiyan Li, Z. F. Liu and Paul K. S. Chan
Org. Biomol. Chem., 2014, Advance Article
DOI: 10.1039/C4OB01763C, Paper
D-Ribose was converted into 3 novel carbobicyclic nucleosides bearing a bicyclo[4.3.0]nonane framework in 16–19 steps with 5–12% overall yields involving a Wittig olefination and an intramolecular Diels–Alder reaction as the key steps.
Organic & Biomolecular Chemistry - Information Point

Search this Journal

Find an Issue

Organic & Biomolecular Chemistry (2003-Present)
Year *

Find an Article


Related News

The Ugi reaction was one of the very first multicomponent reactions exploited to develop chemical libraries, which further extended to combinatorial, ...
During the months April – June 2014, the most downloaded Organic & Biomolecualr Chemistry articles were: Design, synthesis, and application of tar...
The best content for researchers, readers and scientists in academia, industry and beyond. That’s what to expect from our ever-expanding publishing pr...
RSC Publishing Blog 30 Sep 2014
Congratulations to the winners of the poster prizes at the 25th Symposium on Physical Organic Chemistry (Japan), which was held September 7th to Septe...