Close Icon
Scheduled maintenance work on Thursday 19th January 2016 between 00:00 and 06:00 hours (GMT)
One of our internet service providers will be performing maintenance upgrade work on their network which means you may experience an intermittent reduction in performance, with the possibility of our publishing platform services being offline temporarily. If you have any questions, please use the feedback button on this page. We apologise for any inconvenience this might cause and thank you for your patience.
Journal cover: Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry

Rapid publication of high quality organic chemistry research
  • Advance Articles
  • |
  • Accepted Manuscripts
  • |
  • All Recent Articles
Prev Pg 1 of 5 Next
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C7OB00030H, Communication
A convenient metal-free decarbonylative alkylation-aminoxidation of styrene derivatives with aliphatic aldehydes and N-hydroxyphthalimide (NHPI) to yield phthalimide protected alkoxyamines is developed. With DTBP as an oxidant and radical-initiator, this reaction...
Mar Ríos-Gutiérrez, Andrea Daru, Tomas Tejero, Luis R. Domingo and Pedro Merino
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C6OB02768G, Paper
The [3+2] cycloaddition (32CA) reaction between nitrones and ketenes has been studied within the Molecular Electron Density Theory (MEDT) at the Density Functional Theory (DFT) MPWB1K/6-311G(d,p) computational level. Analysis of...
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02652D, Paper
A high-yielding, cost-effective, modular and environmentally benign approach to [5,5]- or [6,5]-2-azabicyclic architectures bearing vicinal stereocenters, by Fe-catalyzed dehydrative coupling of readily affordable alcohol-bearing allylic lactams is presented.
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02729F, Paper
Novel benzoselenophene analogs of duocarmycin were prepared. The anticancer activity of the butyramide analog of benzoselenophene was 120 times more potent than the corresponding indole analog.
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02533A, Communication
Alkyl-substituted isoquinoline-1,3(2H,4H)-diones were prepared by coupling of N-alkyl-N-methacryloylbenzamides and aliphatic aldehydes through subsequent decarbonylation, radical addition and cyclization processes.
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02109C, Paper
The structures, interaction energies and thermodynamics of the complex formation between mianserin (MIA) and β-cyclodextrin (β-CD) are investigated using computational methods and calorimetric measurements.
Xing Zhang, Yongmei Xu, Po-Hung Hsieh, Jian Liu, Lei Lin, Eric P. Schmidt and Robert J. Linhardt
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02603F, Paper
A heparin oligosaccharide having a completely natural structure was successfully synthesized through a chemoenzymatic approach using an unnatural glycosyl acceptor, p-nitrophenyl glucuronide (GlcA-pNP).
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02627C, Communication
A Cu-catalyzed protocol is described for the transformation of oximes to the corresponding carbonate derivatives.
Thomas Hanauer, Richard J. Hopkinson, Kamal Patel, Yu Li, Danilo Correddu, Akane Kawamura, Vijayalekshmi Sarojini, Ivanhoe K. H. Leung and Tobias Gruber
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02616H, Communication
We report a simple carboxycalixarene that selectively binds molecules containing di/trimethylammonium moieties in isolation, in cell lysates and when incorporated in histone peptides.
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C6OB02655A, Communication
An efficient access to optically active sulfahydantoins, 4-aryl-1,2,5-thiadiazolidin-3-one 1,1-dioxides, was developed through palladium-catalyzed asymmetric hydrogenation of the corresponding cyclic N-sulfonylketimines with up to 98% ee.
Takashi Kanamori, Akihiro Takamura, Nobuhiro Tago, Yoshiaki Masaki, Akihiro Ohkubo, Mitsuo Sekine and Kohji Seio
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB01278G, Paper
Green fluorescent protein (GFP)-based molecular-rotor chromophores were attached to the deoxyuridines and incorporated into the oligodeoxynucleotides.
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02427K, Paper
Electronic and steric effects each play important roles in determining the base strength in piperidines.
C. Fraschetti, M. Montagna, M. E. Crestoni, A. Calcaterra, F. Aiello, L. Santi and A. Filippi
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02734B, Paper
Protonated basket resorcin[4]arenes are suitable for enantiodiscrimination of alanine di- and tripeptides in the gas phase.
Kunfeng Li, Jiali Deng, Hongwei Jin, Xiantao Yang, Xinmeng Fan, Liyu Li, Yi Zhao, Zhu Guan, Yun Wu, Lihe Zhang and Zhenjun Yang
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02577C, Paper
The aptamer GBI-10 has been modified with D-/L-isoNA or 2′-dI, and its tumor targeting ability in vivo is obviously improved by 4AL/26TL/32TL substitutions.
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C6OB02782B, Communication
A palladium-catalyzed carbonylative intramolecular synthesis of benzofuran-2(3H)-ones from 2-hydroxybenzyl alcohols has been developed. In this procedure, formic acid has been utilized as the CO source, and various desired benzofuran-2(3H)-one derivatives...
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C6OB02671K, Paper
Here we report a microwave assisted Ru(III)/TBHP-mediated reaction of indoles with tetramethylurea (TMU) synthesizing symmetrical as well as unsymmetrical bis(indolyl)methanes, where TMU acts as a methylenating agent. This is the...
Mathieu Esgulian, Vincent Belot, Régis Guillot, Sandrine Deloisy and David J Aitken
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C6OB02759H, Paper
A number of cyclic derivatives of 3-amino-2,4-dihydroxybutanoic acid are known in the literature but they are often prepared from other cyclic substrates. This study showed that the title compound too...
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C6OB02670B, Paper
Bacterial rare amino deoxy sugars are found in the cell surface polysaccharides of multiple pathogenic bacterial strains, but are absent in the human metabolism. This helps in the differentiation between...
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C7OB00026J, Paper
A rhodium-catalyzed Weinreb amide directed cross-coupling reaction between electron-deficient alkenes is reported, which provides an efficient route for the synthesis of valuable and versatile Weinreb amide functionalized (Z,E)-butadienes. The catalytic...
Man-Yi Han, Fei-Yan Yang, Di Zhou and Zhigang Xu
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C7OB00005G, Paper
A highly efficient [1,2]-Brook rearrangement of silyl glyoxylates has been developed using DBU as the organobase-catalyst. This [1,2]-Brook rearrangement is applicable to a number of thiols and secondary phosphine oxides...
Kazuma Oda, Satoru Hiroto, Ichiro Hisaki and Hiroshi Shinokubo
Org. Biomol. Chem., 2017, Accepted Manuscript
DOI: 10.1039/C6OB02775J, Paper
Introduction of a dicyanomethyl anion group to hexa-peri-hexabenzocoronene (HBC) substantially enhanced the emission property of HBC due to large perturbation of its electronic structure. In addition, dicyanoetheno-bridged HBC dimers obtained...
C. A. Dannenberg, L. Fritze, F. Krauskopf and C. Bolm
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02691E, Communication
Sulfoxides are stereospecifically converted to N-cyanosulfoximines using N-chlorosuccinimide (NCS) as oxidising agent and cyanamide as nucleophilic amine source.
Ivan Yanachkov, Boris Zavizion, Valeri Metelev, Laura J. Stevens, Yekaterina Tabatadze, Milka Yanachkova, George Wright, Anna M. Krichevsky and David R. Tabatadze
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02576E, Paper
There is tremendous potential for oligonucleotide (ON) therapeutics, but low cellular penetration due to their polyanionic nature is a major obstacle.
Loida O. Casalme, Arisa Yamauchi, Akinori Sato, Julie G. Petitbois, Yasuyuki Nogata, Erina Yoshimura, Tatsufumi Okino, Taiki Umezawa and Fuyuhiko Matsuda
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02657E, Paper
The total synthesis of dolastatin 16, a macrocyclic depsipeptide first isolated from the sea hare Dolabella auricularia as a potential antineoplastic metabolite by Pettit et al., was achieved in a convergent manner.
Chengqian Pan, Yutong Shi, Xuegang Chen, Chen-Tung Arthur Chen, Xinyi Tao and Bin Wu
Org. Biomol. Chem., 2017, Advance Article
DOI: 10.1039/C6OB02374F, Paper
Three new quinazoline derivatives (1–3), one new oxepin-containing natural product (4) and four new cyclopenin derivatives (5–7 and 9) have been isolated from an EtOAc extract of the Taiwan Kueishantao hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4.
Organic & Biomolecular Chemistry - Information Point

Search this journal

Find an issue

Organic & Biomolecular Chemistry (2003-Present)
Year *

Find an article


Citation velocity

Articles from this journal that are regularly and recently being cited by others. We are trialling this feature to see if it makes it quicker and easier for you to find articles for your research. Read more about how we have created this filtering system.

21 citations
A unified strategy for the palladium-catalyzed Suzuki–Miyaura cross-coupling of amides with boronic acids for the synthesis of ketones by N–C bond activation is reported.
DOI: 10.1039/C6OB00084C
Published: 11 Feb 2016
54 citations
The recent advances in the copper-catalysed azide–alkyne cycloaddition (CuAAC) reactions are reviewed.
DOI: 10.1039/C5OB01457C
Published: 31 Jul 2015
46 citations
This review article covers the main types of gold(i) complexes used as precatalysts under homogeneous conditions in organic synthesis and discusses the different ways of catalyst activation as well as ligand, silver, and anion effects.
DOI: 10.1039/C5OB00736D
Published: 19 May 2015

Related news