Publishing: Journals, books and databases
Journal cover: Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry

Rapid publication of organic chemistry research
Impact Factor 3.562 48 Issues per Year Indexed in Medline
  • Advance Articles
  • |
  • Accepted Manuscripts
  • |
  • All Recent Articles
Prev Pg 1 of 6 Next
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02192H, Paper
3-(2-bromoethyl)indole reacts with 2,3-dimethylimidazole-1-sulfonyl azide triflate to give an intermediate: N-(2,3-dimethylimidazole)-1-sulfonyl aza-spirocyclopropanyloxindole. This reactive species is captured by alcohol or amine to afford corresponding aza-spiroxindole sulfonate and sulfonamide.
Ngoc Thang, Frank Janert, Peter Ehlers, Do H Hoang, Tuan T Dang, Alexander Villinger, Stefan Lochbrunner and Peter Langer
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02274F, Paper
A series of new 7- and 4-azaindolo[1,2-f]phenanthridines were synthesized by a domino Pd(0)-catalyzed reaction, which involves three sequential steps: C-N coupling, hydroamination, and intramolecular C-H arylation. The products show promising...
David O'Hagan, Tanya Bykova, Nawaf Al-Maharik and Alexandra Slawin
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02334C, Paper
This paper reports the preparation of methyl substituted all-cis tetrafluorocyclohexanes prepared from a Birch reduction of benzoic acid, worked up with a methyl iodide quench. The resultant methylcyclohexadiene carboxylic acid...
Rama P Tripathi, Kapil Upadhyaya, Hamid Ullah, Kartikey Singh, Ashutosh Arun, Mahendra Shukla, Neetika Srivastav, Raghib Ashraf, Abhisheak Sharma, Rohit Mahar, Sanjeev Kumar Shukla, Jayanta Sarkar, Ravishankar Ramachandran, Jawahar Lal and Rituraj Konwar
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02113H, Paper
A novel class of gallic acid based glycoconjugates were designed and synthesized as potential anticancer agents by economical and eco-friendly method. Among all the compounds screened, compound 2a showed potent...
Eunsun Kim, Abdellah Felouat, Elena Zaborova, Jean-Charles Ribierre, Jeong Weon Wu, Sebastien Senatore, Cedric Matthews, Pierre-François Lenne, Carole Baffert, Artak Karapetyan, Michel Giorgi, Denis Jacquemin, Miguel Ponce-Vargas, Boris Le Guennic, Frederic Fages and Anthony D'Aleo
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02295A, Paper
Hemicurcuminoids are based on half of the π-conjugated backbone of curcuminoids. The synthesis of a series of such systems and their borondifluoride complexes is described. The electrochemical and photophysical properties...
warapong senapak, Rungnapha Saeeng, jaray jaratjaroonphong, Teerapich Kasemsuk and uthaiwan sirion
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB01953B, Paper
A mild, efficient and metal-free method was described for the green synthesis of dipyrromethanes from aldehydes and unsubstituted pyrrole catalyzed by SO3H-functionalized ionic liquids (SO3H-ILs) in water media at room...
Ganesan Vaidyanathan, Darryl McDougald, Jaeyeon Choi, Marek Pruszynski, Eftychia Koumarianou, Zhengyuan Zhou and Michael R. Zalutsky
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02258D, Paper
Residualizing labeling methods for internalizing peptides and proteins are designed to trap the radionuclide inside the cell after intracellular degradation of the biomolecule. The goal of this work was to...
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02216A, Paper
A practical and economical K2S2O8-mediated oxidative cross-dehydrogenative coupling of N-aryl glycine derivatives with olefins has been established, affording structurally diverse quinoline-2-carboxylates in good to high efficiency. The low cost, negligible...
Yoko Yasuno, Makoto Hamada, Masanori Kawasaki, Keiko Shimamoto, Yasushi Shigeri, Toshifumi Akizawa, Motomi Konishi, Yasufumi Ohfune and Tetsuro Shinada
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02301G, Communication
Structure-activity relationship (SAR) study of kaitocephalin known to be a potent naturally occuring NMDA receptor ligand was performed. This study led us to the discovery of (7S)-kaitocephalin as a highly...
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB01915J, Paper
This new microwave-assisted method provides a quick one-pot borylation/Suzuki protocol that does not require additional ligands nor double loading of catalyst.
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB01970B, Communication
A Pd(II)-catalyzed intramolecular oxidative Heck dearomative reaction for the construction of thiazole-fused pyrrolidinones was achieved for the first time.
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02362A, Paper
A formal γ-allylation of deconjugated butenolides is reported based on a two-step sequence consisting of a catalytic diastereo- and enantioselective vinylogous nucleophilic addition to vinyl sulfones and JuliaKocienski olefination. This...
Margaret A Brimble, Luis M De Leon Rodriguez and Harveen Kaur
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02298C, Review Article
Mycobacterium tuberculosis is the causative agent of tuberculosis (TB), an infection that has been declared a global public health emergency by the World Health Organization. Current anti-TB therapeutic measures are...
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB02330K, Communication
An enantioselective palladium-catalyzed arylation of N-tosylarylimines with arylboronic acids was developed by using an axially chiral 2,2′-bipyridine ligand C3-ACBP, affording chiral diarylmethamines with up to 94% ee under exogenous-base-free conditions.
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB02323H, Communication
UbH2A was prepared from recombinant H2A containing azidonorleucine 119 and incorporated into nucleosomes to study DUBs and H3K36 MTases.
Xu-Dong Wang, Sen Li, Yu-Fei Ao, Qi-Qiang Wang, Zhi-Tang Huang and De-Xian Wang
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB02291F, Paper
Heteracalixaromatics are a new generation of macrocyclic hosts showing a unique structure and versatile recognition properties towards various guests.
Hua Zhang, Jia Liu, Li-She Gan, Seema Dalal, Maria B. Cassera and Jian-Min Yue
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB02296G, Paper
Five new diterpenoid dimers of a rare structure class were discovered from Aphanamixis grandifolia. These compounds showed moderate antimalarial activities.
Raghunathreddy Anugu, Prathama S Mainka, Sridhar Balasubramanian and Chandrasekhar Srivari
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02047F, Paper
(±)-Asenapine, sold in the market as Saphris/Sycrest for the treatment of bipolar disorders is synthesized in optically pure form involving Ireland-Claisen rearrangement as the key step. This approach allows access...
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02328A, Paper
Aminooxyl sugar derivatives are versatile building blocks for the generation of various glycoconjugates with interesting bioactivities. We report herein a synthetic method for the preparation of orthogonally protected glycoaminooxy acid...
Alexander S. Bogachenkov, Albina V. Dogadina, Irina A. Boyarskaya, Vadim P. Boyarskiy and Aleksander Vasilyev
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02143J, Paper
1-(Diphenylphosphoryl)alka-1,2-dienes (phosphonoallenes) in Bronsted (super)acids (TfOH, FSO3H, H2SO4) gave corresponding 1,2-oxaphosphol-3-enium ions, that were characterized by means of NMR and DFT calculations. Upon hydrolysis of reaction solution, these cations afforded...
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB02263K, Communication
The synthesis of α-aryl and alkenyl pyrrolidine-, piperidine-, and azepane derivatives by ruthenium-catalyzed, carbonyl-assisted, site-selective sp2 C–H activation of cyclic enamides and concomitant cross-coupling with boronic acids is described.
Ilkay Bora, Sidsel Ammitzbøll Bogh, Martin Rosenberg, Marco Santella, Thomas J. Sørensen and Bo W. Laursen
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02293B, Paper
The azaoxa-triangulenium dyes are characterised by emission in the red and a long fluorescence lifetime (up to 25 ns). These properties have been widely explored for the azadioxatrianguelnium (ADOTA) dye....
Atsushi Kato, Izumi Nakagome, Kasumi Sato, Arisa Yamamoto, Isao Adachi, Robert J. Nash, George W J Fleet, Yoshihiro Natori, Yasuka Watanabe, Tatsushi Imahori , Yuichi Yoshimura, Hiroki Takahata and Shuichi Hirono
Org. Biomol. Chem., 2015, Accepted Manuscript
DOI: 10.1039/C5OB02223A, Paper
We report on the synthesis and biological evaluation of a series of α-1-C-alkylated 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) derivatives as pharmacological chaperones for Gaucher disease. The parent compound, DAB, did not show inhibition...
Socrates B. Munoz, Alexandra N. Aloia, Alexander K. Moore, Attila Papp, Thomas Mathew, Santos Fustero, George A. Olah and G. K. Surya Prakash
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB02187A, Paper
From themed collection 2015 Hot Articles in Organic and Biomolecular Chemistry
Reports the synthesis of 3-methylene-isoindolin-1-ones 4 under aqueous phase-transfer conditions.
C. Guzzi, P. Alfarano, I. Sutkeviciute, S. Sattin, R. Ribeiro-Viana, F. Fieschi, A. Bernardi, J. Weiser, J. Rojo, J. Angulo and P. M. Nieto
Org. Biomol. Chem., 2016, Advance Article
DOI: 10.1039/C5OB02025E, Paper
Multiple binding modes at the same binding site can explain the higher binding affinity of a pseudotrimannotrioside compared to a pseudomannobioside.
Organic & Biomolecular Chemistry - Information Point

Search this journal

Find an issue

Organic & Biomolecular Chemistry (2003-Present)
Year *

Find an article


Related news

Organic & Biomolecular Chemistry is delighted to announce a call for paper for its latest themed issue on: Selective Chemistry with Peptides and P...
Organic & Biomolecular Chemistry , our sister journal, publishes many articles that cover a variety of natural product chemistry. We try to keep y...
Natural Products Blog 19 Nov 2015
The articles below are the most read Organic & Biomolecular Chemistry articles in July, August and September 2015. Linear and star-shaped pyrazine...
The 2016 RSC Prizes and Awards are now open for nomination! Nominations will close on 15 January 2016. For more than 140 years, our Prizes and Awards ...