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Journal cover: Metallomics

Metallomics

Global approaches to metals in the biosciences
Impact Factor 3.585 12 Issues per Year Indexed in Medline
 
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Ekaterina Schreiber-Brynzak, Verena Pichler, Petra Heffeter, Buck Hanson, Sarah Theiner, Irene Lichtscheidl-Schultz, Christoph Kornauth, Luca Bamonti, Vineet Dhery, Diana Groza, David Berry, Walter Berger, Markus Galanski, Michael A. Jakupec and Bernhard K. Keppler
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00312A, Paper
Bioreductive platinum(IV) prodrugs target tumor hypoxia.
 
Wenjing Zhang, Xinmei Zhao, Ying Xiao, Jianmin Chen, Pengfei Han, Jingyao Zhang, Haiying Fu and Y. James Kang
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00332F, Paper
Copper loss in ischemic myocardium makes a critical contribution to the suppression of HIF-1-regulated angiogenesis.
 
Melchior Cini, Huw Williams, Mike W. Fay, Mark S. Searle, Simon Woodward and Tracey D. Bradshaw
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT90005D, Correction
 
Hendrik Küpper and Elisa Andresen
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00244C, Critical Review
Metal toxicity in plants is still a global problem for the environment, agriculture and ultimately human health.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00295H, Paper
The metal transportome of Cupriavidus metallidurans. Seven secondary metal uptake systems (top) provide transition metal cations to the cell. The number of metal atoms per cell are shown in the middle of the cell. Below, the metal efflux systems for the transition metal cations are indicated.
 
Gaopeng Li, Liying Liu, Ping Li, Luonan Chen, Haiyun Song and Yan Zhang
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00134J, Paper
Transcriptome analysis of SPS2 knockdown suggests a new relationship between selenium utilization and fundamental cellular processes as well as diseases.
 
Stéphanie Guigues, Matthieu N. Bravin, Cédric Garnier, Armand Masion, Claire Chevassus-Rosset, Patrick Cazevieille and Emmanuel Doelsch
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00298B, Paper
A dual local environment of Cu in root apoplasts was identified.
 
J. E. J. Hardyman, J. Tyson, K. A. Jackson, C. Aldridge, S. J. Cockell, L. A. Wakeling, R. A. Valentine and D. Ford
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00305A, Paper
Without MTF1, zinc buffering by metallothioneins is reduced; hence, the sensitivity of the non-MTF1-controlled zinc-responsive transcriptome is augmented.
 
Melchior Cini, Huw Williams, Mike W. Fay, Mark S. Searle, Simon Woodward and Tracey D. Bradshaw
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00297D, Paper
Enantiopure titanocene complexes exert selective antitumour activity evoking paraptosis. HPLC, MS and NMR revealed CpR2Ti(OH)(OH2)+ as the likely trigger.
 
Sarah Theiner, Ekaterina Schreiber-Brynzak, Michael A. Jakupec, Markus Galanski, Gunda Koellensperger and Bernhard K. Keppler
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00276A, Communication
A novel application of advanced elemental imaging offers cutting edge in vitro assays with more predictive power on the efficacy of anticancer drugs in preclinical development compared to two dimensional cell culture models.
 
Tanara V. Peres, Lin K. Ong, Ana Paula Costa, Helena Eyng, Débora K. R. Venske, Dirleise Colle, Filipe M. Gonçalves, Mark W. Lopes, Marcelo Farina, Michael Aschner, Phillip W. Dickson, Peter R. Dunkley and Rodrigo B. Leal
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00265F, Paper
Mn induces short- and long-term alterations on striatal tyrosine hydroxylase levels and phosphorylation in rats.
 
N. V. Dolgova, M. J. Hackett, T. C. MacDonald, S. Nehzati, A. K. James, P. H. Krone, G. N. George and I. J. Pickering
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00279F, Paper
Selenium is found to be highly concentrated in zebrafish pigment (melanin) containing tissues especially for the organic selenium treatments, with lower concentrations in eye lens, yolk sac and heart.
 
Shikha Verma, Pankaj Kumar Verma, Alok Kumar Meher, Sanjay Dwivedi, Amit Kumar Bansiwal, Veena Pande, Pankaj Kumar Srivastava, Praveen Chandra Verma, Rudra Deo Tripathi and Debasis Chakrabarty
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00277J, Paper
The study explores new insights into the arsenic metabolism by WaarsM and provides a potential approach for the bioremediation process.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00267B, Paper
Embryonic exposure to Pb at levels as low as 10 μg L−1 disturb global gene expression patterns in a sex-specific manner.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00291E, Paper
Structural-functional platform unravels new roles for ZinT in cobalt, mercury and cadmium resistance, providing clues into the metal binding mechanism.
 
M. C. Carpenter, A. Shami Shah, S. DeSilva, A. Gleaton, A. Su, B. Goundie, M. L. Croteau, M. J. Stevenson, D. E. Wilcox and R. N. Austin
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00209E, Paper
The first quantification of Pb(II) binding to MT-3 using ITC shows that lead binds more tightly than zinc to this brain-specific metallothionein.
 
Mariana S. de Camargo, Monize M. da Silva, Rodrigo S. Correa, Sara D. Vieira, Silvia Castelli, Ilda D'Anessa, Rone De Grandis, Eliana Varanda, Victor M. Deflon, Alessandro Desideri and Alzir A. Batista
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00227C, Paper
New cytotoxic ruthenium(II) compounds with mercaptopyridine derivatives inhibit human DNA topoisomerase IB and interact moderately with DNA and BSA macromolecules.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00300H, Critical Review
This critical review focuses on one possible link between the cellular biology of lead and its neurotoxic effects: the link between Pb2+ substitution for Zn2+ in zinc-finger proteins and mental illness in adulthood.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00257E, Paper
Unexpectedly, monitoring cytosolic and ER Zn2+ using FRET sensor proteins does not support EGF–ionomycin-triggered Zn2+ waves in breast cancer cells.
 
Mai Thanh Quynh Tran, Stefan Stürup, Ian Henry Lambert, Bente Gammelgaard, Evelyne Furger and Roger Alberto
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00272A, Paper
Cellular uptake of vitamin B12-cisplatin conjugates was estimated via detection of their metal constituents (Co, Pt, and Re) by inductively coupled plasma mass spectrometry (ICP-MS).
 
M.-J. Hosseini, I. Jafarian, S. Farahani, R. Khodadadi, S. H. Tagavi, P. Naserzadeh, A. Mohammadi-Bardbori and N. Arghavanifard
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00249D, Paper
Scheme of proposed mechanisms for Pd2+ -induced mitochondrial toxicity.
 
Yunyun Li, Jiating Zhao, Yu-Feng Li, Xiaohan Xu, Bowen Zhang, Yongjie Liu, Liwei Cui, Bai Li, Yuxi Gao and Zhifang Chai
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00264H, Paper
The toxicity mechanisms of rice roots under inorganic mercury (IHg) or methylmercury (MeHg) stress were investigated using metalloproteomic approaches.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00251F, Critical Review
Platelets are known to be activated by exogenous zinc. Herein we discuss the potential routes for zinc entry and the role of zinc–protein interactions in platelet activation.
 
Stuart D. Portbury, Dominic J. Hare, Charlotte Sgambelloni, David I. Finkelstein and Paul A. Adlard
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00234F, Paper
A LA-ICP-MS time course study of changing metal concentrations following traumatic brain injury in mice.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00167F, Paper
Comparison of titration of the fluorescent metal ion sensor Newport Green acid with Zn2+ in the absence (red) and presence (blue) of cell proteome. The proteome strongly competes with Newport Green for Zn2+.
 

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