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Journal cover: Metallomics

Metallomics

Global approaches to metals in the biosciences
Impact Factor 3.54 12 Issues per Year Indexed in Medline
 
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Francis Albarede, Philippe Telouk, Vincent Balter, Victor Paky Bondanese, Emmanuelle Albalat, Philippe Oger, Paola Bonaventura, Pierre Miossec and Toshiyuki Fujii
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C5MT00316D, Critical Review
This review examines recent applications of stable copper, zinc and sulfur isotopes to medical cases and notably cancer. The distribution of the natural stable isotopes of a particular element among...
 
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C6MT00117C, Paper
Alzheimer’s disease (AD) is characterized by the production of large amounts of beta-amyloid (Aβ) and the accumulation of extracellular senile plaques, which have been considered to be potential targets in...
 
José Argüello, Sarju J Patel and Julia Quintana Gonzalez
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C6MT00089D, Critical Review
From themed collection Mammalian Copper Transport and Related Disorders
The early discovery of the human Cu+-ATPases and their link to Menkes and Wilson’s diseases brought attention to the unique role of these transporters in copper homeostasis. The characterization of...
 
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C6MT00111D, Perspective
From themed collection Mammalian Copper Transport and Related Disorders
The nineties have witnessed the discovery of the copper ATPases, enzymes which transport copper across the cytoplasmic membranes of bacteria and eukaryotes. In the same decade, several other key components...
 
Gemma Kate Gransbury, Peter kappen, Chris J Glover, James N Hughes, Aviva Levina, Peter A Lay, Ian Musgrave and Hugh Harris
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C6MT00145A, Paper
NAMI-A and KP1019 are RuIII-based anti-metastatic and cytotoxic anti-cancer drugs, respectively, and have been proposed to be activated by reduction to RuII. The potential reduction of NAMI-A and KP1019 in...
 
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C6MT00049E, Paper
Microalgae use various cellular mechanisms to detoxify both non-essential and excess essential metals or metalloids. There exists however, a threshold in intracellular metal/metalloid concentrations beyond which detoxification mechanisms are no...
 
Mathilde L. Bonnemaison, Megan E. Duffy, Richard E. Mains, Stefan Vogt, Betty A. Eipper and Martina Ralle
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00079G, Paper
From themed collection Mammalian Copper Transport and Related Disorders
Rodent pituitaries were subjected to subcellular fractionation. Secretory granule Cu, Zn and Ca levels were compared to levels of peptide amidating monooxygenase, a peptide processing enzyme requiring all three metals.
 
David Freestone, Delphine Denoyer, Matthew Jakab, M. Leigh Ackland, Michael A. Cater and Agnes Michalczyk
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00086J, Paper
From themed collection Mammalian Copper Transport and Related Disorders
PMC42-LA three-dimensional organoids reminiscent of mammary gland alveoli secrete copper-bound ceruloplasmin (sCP) in both lactating and suckled models.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00103C, Critical Review
From themed collection Mammalian Copper Transport and Related Disorders
We know that blood plasma contains many proteins and also other components that bind copper.
 
Joseph R. Prohaska
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT90026G, Editorial
From themed collection Mammalian Copper Transport and Related Disorders
Joseph Prohaska reflects on a career in copper research.
 
Julian F. B. Mercer and James Camakaris
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT90022D, Editorial
From themed collection Mammalian Copper Transport and Related Disorders
Julian Mercer and Jim Camakaris discuss the history and impact at the international level of copper research in Australia and particularly Melbourne.
 
M. A. Greenough, A. Ramírez Munoz, A. I. Bush and C. M. Opazo
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00095A, Minireview
From themed collection Mammalian Copper Transport and Related Disorders
Copper is an essential metal ion that provides catalytic function to numerous enzymes and also regulates protein trafficking, neurotransmission and intracellular signaling.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00099A, Paper
From themed collection Mammalian Copper Transport and Related Disorders
It is unclear why ubiquitous expression of mutant SOD1 selectively affects the central nervous system in amyotrophic lateral sclerosis. Here we hypothesise that the central nervous system is primarily affected because, unlike other tissues, it has relatively limited capacity to satiate an increased requirement for Cu.
 
N. S. Ghatpande, P. P. Apte, S. S. Naik, B. N. Joshi, M. K. Gokhale and P. P. Kulkarni
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00129G, Communication
Under anemic conditions, B12 deficiency leads to higher tumor necrosis factor (TNF-α) levels among adolescent girls.
 
Elena V. Polishchuk and Roman S. Polishchuk
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00058D, Minireview
From themed collection Mammalian Copper Transport and Related Disorders
The lysosomal system operates as a focal point where a number of important physiological processes such as endocytosis, autophagy and nutrient sensing converge.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00093B, Paper
From themed collection Mammalian Copper Transport and Related Disorders
The ATP7A protein is a ubiquitous copper-transporting P-type ATPase that is mutated in the lethal pediatric disorder of copper metabolism, Menkes disease.
 
Kyung Chan Park, Leyla Fouani, Patric J. Jansson, Danson Wooi, Sumit Sahni, Darius J. R. Lane, Duraippandi Palanimuthu, Hiu Chuen Lok, Zaklina Kovačević, Michael L. H. Huang, Danuta S. Kalinowski and Des R. Richardson
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00105J, Critical Review
From themed collection Mammalian Copper Transport and Related Disorders
Copper is an essential trace metal required by organisms to perform a number of important biological processes.
 
Irina Naletova, Vincenzo G. Nicoletti, Danilo Milardi, Adriana Pietropaolo and Giuseppe Grasso
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00067C, Paper
The conformation and oligomerization state of BK are strongly affected by copper but not zinc and this in turn affects the activity of BK in cells.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00021E, Paper
Copper containing fungicides are used to protect vineyards from fungal infections.
 
Gonzalo Perez-Siles, Adrienne Grant, Melina Ellis, Carolyn Ly, Aditi Kidambi, Mamdouh Khalil, Roxana M. Llanos, Sharon La Fontaine, Alleene V. Strickland, Stephan Züchner, Sandra Bermeo, Elysia Neist, Tara C. Brennan-Speranza, Reinaldo I. Takata, Carlos E. Speck-Martins, Julian F. B. Mercer, Garth A. Nicholson and Marina L. Kennerson
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00082G, Paper
From themed collection Mammalian Copper Transport and Related Disorders
We have generated an Atp7a conditional knock in mouse model of dHMNX expressing Atp7aT985I, the orthologue of the human ATP7AT994I identified in dHMNX patients.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00051G, Paper
A new selenium supplementation regimen was applied to probe the response of the urinary selenium species and improve the understanding of selenium metabolism.
 
Chelsey D. Kline, Benjamin F. Gambill, Mary Mayfield, Svetlana Lutsenko and Ninian J. Blackburn
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00062B, Communication
Cuproproteins such as PHM and DBM mature in late endosomal vesicles of the mammalian secretory pathway where changes in vesicle pH are employed for sorting and post-translational processing.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00037A, Paper
From themed collection Mammalian Copper Transport and Related Disorders
In response to ischemic conditions, Cu redistribution takes place although Cu concentration was decreased, leading to depressed Cu-dependent CCO activity but increased Cu-dependent LOX activity in the ischemic myocardium along with enhanced collagen deposition.
 
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00045B, Paper
Vanadium complexes were studied during recent years and considered as a representative of a new class of non-platinum metal antitumor agents in combination with their low toxicity.
 
Kristin M. Bompiani, Cheng-Yu Tsai, Felix P. Achatz, Janika K. Liebig and Stephen B. Howell
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00076B, Paper
From themed collection Mammalian Copper Transport and Related Disorders
We used CRISPR-Cas9 technology to address whether copper transporters or chaperones CTR1, CTR2, ATOX1, and CCS mediate cisplatin sensitivity in human cells.
 

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20 citations
Toxic metal(loid) contamination of soil and sediment poses long term risk to soil and human health through plant–human or plant–animal–human food chain pathways.
DOI: 10.1039/C4MT00111G
Published: 13 Jun 2014
1 citations
The molecular mechanism of CeONPs in protecting against neuronal cytotoxicity from amyloid peptides and copper ions was investigated systematically by photoluminescence of [Ru(phen)2dppz]2+, morphology of TEM, mass spectroscopy, cell viability assay, ROS fluorescence assay, and EPR.
DOI: 10.1039/C5MT00242G
Published: 25 Nov 2015
13 citations
Mercury hepatotoxicity was investigated in wild fish (Liza aurata) through assessment of metabolomic shifts, antioxidant system and Hg bioaccumulation.
DOI: 10.1039/C5MT00090D
Published: 04 Jun 2015

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