Journal cover: Metallomics


Global approaches to metals in the biosciences
Impact Factor 3.978 12 Issues per Year Indexed in MEDLINE
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Marek Luczkowski, Riccardo De Ricco, Monika Stachura, Slawomir Potocki, Lars Hemmingsen and Daniela Valensin
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00274A, Paper
Soft metal ion binding enforces critical rearrangement of the structure of Bri2-23, a natural inhibitor of Aβ aggregation, thus shifting its solution behavior to a self aggregating system.
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00312H, Paper
A series of ruthenium(II) benzimidazole complexes has been synthesized and identified as antiangiogenic agents with distinct structure-based action mechanisms.
Franziska Schwabe, Simon Tanner, Rainer Schulin, Aline Rotzetter, Wendelin Stark, Albrecht von Quadt and Bernd Nowack
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00343H, Paper
Cerium uptake into plants in the presence of CeO2 nanoparticles occurs not only in nanoparticulate form, but also as dissolved ions.
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00001G, Paper
CueO from Escherichia coli is a multicopper oxidase (MCO) involved in copper tolerance under aerobic conditions. It features the four typical copper atoms that act as electron transfer (T1) and...
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00339J, Minireview
Parkinson’s disease (PD) is the most frequent neurodegenerative movement disorder with severe consequences for patients and caregivers. In the last twenty years of research, alpha-synuclein (αSyn) emerged as a main...
Jing Wang, Ru Bai, Ru Yang, Jing Liu, Jinglong Tang, Jiayang Li, Ying Liu, Zhifang Chai and Chunying Chen
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00340C, Paper
Engineered gold nanoparticles (AuNPs) have recently drawn an increased interest in disease diagnostics and therapies. However, reports on detailed studies of AuNPs regarding pharmacodynamics, pharmacokinetics, biodistribution, metabolism and toxicity potential...
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00315B, Paper
The kidney plays an important role in iron homeostasis and actively reabsorbs citrate. The bifunctional iron-regulatory protein IRP-1 potentially regulates iron trafficking and participates in citrate metabolism as a cytosolic...
Alexander E Egger, Christoph Kornauth, Werner Haslik, Stephan Hann, Sarah Theiner, Guenther Bayer, Christian Hartinger, Bernhard K Keppler, Ursula Pluschnig and Robert M Mader
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00308J, Paper
Platinum-based drugs (cisplatin, carboplatin and oxaliplatin) are widely used in cancer treatment. Although administered intravenously, accidental extravasations of infusions can occur. This may cause severe complications for the patient as...
Patrícia Pereira, Joana Raimundo, Marisa Barata, Olinda Araújo, Pedro Pousão Ferreira, João Canário, Armando Almeida and Mário Pacheco
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00291A, Paper
There are several aspects of inorganic mercury (iHg) toxicokinetics in fish that remain undeveloped despite its environmental ubiquity, bioaccumulation capacity and toxicity. Thus, this study presents the uptake, distribution and...
Marta Albareda, Agnès Rodrigue, Belén Brito, Tomás Ruiz-Argüeso, Juan Imperial, Marie-Andrée Mandrand-Berthelot and Jose Palacios
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00298A, Paper
From themed collection Nickel in biology
Bacteria require nickel transporters for the synthesis of Ni-containing metalloenzymes in natural, low nickel habitats. In this work we carry out a functional and topological characterization of Rhizobium leguminosarum HupE,...
Antoine P. Maillard, Sandra Künnemann, Cornelia Große, Anne Volbeda, Grit Schleuder, Isabelle Petit-Härtlein, Eve de Rosny, Dietrich H. Nies and Jacques Covès
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00293H, Paper
From themed collection Nickel in biology
Atomic-resolution structures illustrate how Ni(II) sensing by CnrXs proceeds by conformational selection to prime signal propagation.
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00310A, Minireview
From themed collection Nickel in biology
Nickel recognition for microbial import exhibits coordination features distinct from other cellular functions.
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00331D, Perspective
The mammalian immune system has evolved sophisticated mechanisms to withhold essential micronutrients from invading pathogens. These processes, collectively known as nutritional immunity serve to limit microbial proliferation and bolster killing...
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00019J, Paper
From themed collection Nickel in biology
The metallochaperone SlyD is essential for nickel delivery to hydrogenase in stationary phase E. coli cells.
Erik Ladomersky and Michael Petris
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00327F, Minireview
Copper (Cu) is an essential trace element for all aerobic organisms. It functions as a cofactor in enzymes that catalyze a wide variety of redox reactions due to its ability...
Marta Costas-Rodriguez, Yulia Anoshkina, Sara Lauwens, Hans Van Vlierberghe, Joris Delanghe and Frank Vanhaecke
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00319E, Paper
The isotopic composition of blood serum Cu has been investigated as a potential parameter for diagnosis and prognosis of liver cirrhosis. Serum samples from supposedly healthy women (reference population) and...
Xiaoshan Shi and K. Heran Darwin
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00305E, Minireview
Copper resistance mechanisms in Mtb during infection and sources of host-provided copper are discussed.
Magdalena Golasik, Wojciech Jawień, Agnieszka Przybyłowicz, Witold Szyfter, Małgorzata Herman, Wojciech Golusiński, Ewa Florek and Wojciech Piekoszewski
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00285G, Paper
Several larynx cancer prediction models were built and each was weighted according to their performance.
Annika Gross, Hamed Alborzinia, Stefania Piantavigna, Lisandra L. Martin, Stefan Wölfl and Nils Metzler-Nolte
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00255E, Paper
Targeting of lysosomes is an interesting, novel pathway for cancer therapy. in this work, novel metallocene derivatives (of ferrocene and ruthenocene) of a cell penetrating polyarginine peptide are presented as lysosomal membrane permeabilization (LMP) agents and their localization and biological activity is investigated in detail.
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00295D, Paper
From themed collection Nickel in biology
Staphylococcus aureus possesses two canonical ABC-importers dedicated to nickel acquisition: the NikABCDE and the CntABCDF systems, active under different growth conditions.
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00306C, Paper
From themed collection Nickel in biology
HypA structural Zn site mutants affect acid survival of Helicobacter pylori.
Zhong Guo, Junlong Han, Xiao-Yan Yang, Kun Cao, Ke He, Gaofei Du, Guandi Zeng, Liang Zhang, Guangchuang Yu, Zhenghua Sun, Qing-Yu He and Xuesong Sun
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00276H, Paper
S. pneumoniae mainly increases cell wall biosynthesis and improves metabolic ability of many biological pathways to combat copper toxicity.
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00304G, Critical Review
Biological functions of vanadium are based on both the vanadate–phosphate analogy and interactions of the oxidovanadium moiety with proteins.
Kevin K. Kumar, Cody R. Goodwin, Michael A. Uhouse, Julia Bornhorst, Tanja Schwerdtle, Michael Aschner, John A. McLean and Aaron B. Bowman
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00223G, Paper
This study uses an untargeted metabolomics approach to identify changes in energetic processes underlying Huntington's disease pathogenesis and Mn neurotoxicity.
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00242C, Paper
The neuronal damage was identified in the basal ganglia despite the absence of copper accumulation in the region.

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