Journal cover: Metallomics

Metallomics

Global approaches to metals in the biosciences
Impact Factor 3.978 12 Issues per Year Indexed in MEDLINE
 
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Metallomics, 2014, Accepted Manuscript
DOI: 10.1039/C4MT00299G, Paper
From themed collection Nickel in biology
Metabolically produced methylglyoxal is a cytotoxic compound that can lead to covalent modification of cellular DNA, RNA and protein. One pathway to detoxify this compound is via the glyoxalase enzyme...
 
Hani Atamna, Marmik Brahmbhatt, Wafa Atamna, Gregory A. Shanower and Joseph M. Dhahbi
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00246F, Paper
Apo-peroxidase requires heme to properly fold into the holoperoxidase. ‘Free’ (or uncommitted) heme is transferred quickly to apo-peroxidase to form the active enzyme; heme from heme-proteins that binds heme with low affinity (or exchangeable) is very slow to transfer; while heme from stable heme-proteins does not transfer.
 
Sónia S Leal, Joana S Cristóvão, Antje Biesemeier, Isabel Cardoso and Cláudio M Gomes
Metallomics, 2014, Accepted Manuscript
DOI: 10.1039/C4MT00278D, Paper
Superoxide dismutase 1 (SOD1) is a Cu/Zn metalloenzyme that aggregates in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder. Correct metal insertion during SOD1 biosynthesis is critical to prevent misfolding;...
 
M. D. Jones, I. Ademi, X. Yin, Y. Gong and D. B. Zamble
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00210E, Paper
From themed collection Nickel in biology
The Helicobacter pylori transcription factor NikR represses two novel gene targets in a nickel-dependent manner.
 
Metallomics, 2014, Accepted Manuscript
DOI: 10.1039/C4MT00275J, Paper
The mechanisms of zinc to protect the cells against acetic acid toxicity and how zinc acts as an antioxidant are still not clear. Here we present results of metabolic profiling...
 
Pan Chen, Margaret R DeWitt, Julia Bornhorst, FAA Soares, Somshuvra Mukhopadhyay, Aaron B Bowman and Michael Aschner
Metallomics, 2014, Accepted Manuscript
DOI: 10.1039/C4MT00292J, Paper
Parkinson’s Disease (PD) is the second most common neurodegenerative disease, yet its etiology and pathogenesis are poorly understood. PD is characterized by selective dopaminergic (DAergic) degeneration and progressive hypokinetic motor...
 
Robert C. Hider and Wolfgang Maret
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT90051K, Editorial
This editorial introduces a collection of papers presented at a symposium at King’s College London in December 2013. The Iron Metabolism Research Group organized this meeting that focused on “zinc and iron sensing in cells and tissues.
 
Philippe Telouk, Alain Puisieux, Vincent Balter, Victor Bondanese, Toshiyuki Fujii, Anne Pierre Morel, Gille Clapisson, Aline Lamboux and Francis Albarede
Metallomics, 2014, Accepted Manuscript
DOI: 10.1039/C4MT00269E, Paper
The isotope effect describes mass-dependent variations of natural isotope abundances for a particular element. In this pilot study, we measured the 65Cu/63Cu ratios in the serums of 20 breast and...
 
Metallomics, 2014, Accepted Manuscript
DOI: 10.1039/C4MT00253A, Paper
Industrial wastewaters often contain high levels of metal mixtures, in which metal mixtures may have synergistic or antagonistic effects on aquatic organisms. A combination of metallomics and nuclear magnetic resonance...
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT90050B, Editorial
Welcome to issue 1 of 2015, with which we enter our seventh year. We wish you a very Happy New Year from the Metallomics team!
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT90048K, Editorial
Metallomics introduces our Editorial Board members for 2015.
 
Fiona Larner, Laura N. Woodley, Sami Shousha, Ashley Moyes, Emma Humphreys-Williams, Stanislav Strekopytov, Alex N. Halliday, Mark Rehkämper and R. Charles Coombes
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00260A, Paper
Zinc isotope compositions of breast cancer tissue are significantly different compared to healthy breast tissue.
 
Deepika Sharma, Manish Tiwari, Deepika Lakhwani, Rudra Deo Tripathi and Prabodh Kumar Trivedi
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00264D, Paper
Study suggests that arsenic species- and rice cultivar-specific miRNA-dependent regulatory mechanisms play an important role in arsenic stress adaptation and detoxification.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00180J, Perspective
Convergent evidence has emerged over the past decade to highlight the role of manganese as a key player in the defenses that many organisms are building to fight oxidative stress.
 
M. J. Ceko, K. Hummitzsch, N. Hatzirodos, W. M. Bonner, J. B. Aitken, D. L. Russell, M. Lane, R. J. Rodgers and H. H. Harris
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT90049A, Correction
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00288A, Critical Review
Here we review the development and application of fluorescent sensors for studying copper in the brain.
 
Blaine R. Roberts, Dominic J. Hare, Catriona A. McLean, Alison Conquest, Monica Lind, Qiao-Xin Li, Ashley I. Bush, Colin L. Masters, Maria-Christina Morganti-Kossmann and Tony Frugier
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00258J, Communication
Following acute brain injury (<3 hours post-event), cobalt levels in the brain are significantly elevated. This elevation may have important implications for positron emission tomography neuroimaging for assessing brain injury severity.
 
Amanda K. Chaplin, Benedict G. Tan, Erik Vijgenboom and Jonathan A. R. Worrall
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00250D, Paper
In Streptomyces lividans four copZ genes are present encoding CopZ copper chaperones. Under Cu stress CopZ can traffic Cu(I) to CsoR leading to the up-regulation of the CsoR regulon.
 
Yan Fang Zhang, Min Zhang, Xu Lei Huang, Yu Jie Fu, Yu Han Jiang, Ling Ling Bao, Yasen Maimaitiyiming, Guang Ji Zhang, Qian Qian Wang and Hua Naranmandura
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00263F, Paper
Arsenic trioxide has been successfully used for the treatment of patients with acute promyelocytic leukemia (APL) worldwide.
 
Pik Mun Foong, Roghayeh Abedi Karjiban, Yahaya M. Normi, Abu Bakar Salleh and Mohd Basyaruddin Abdul Rahman
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00163J, Paper
The psychrophilic metallome of Glaciozyma antarctica PI12 predicted by bioinformatic approaches.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00265B, Paper
Comparative in situ EPR measurements of four organisms shows that Mn(II) speciation in D. radiodurans favors proteins.
 
Michael R. Jones, Changhua Mu, Michael C. P. Wang, Michael I. Webb, Charles J. Walsby and Tim Storr
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00252K, Paper
The Ru(III) complex KP1019 modulates the aggregation profile of the Alzheimer's Aβ peptide and limits Aβ toxicity in the SH-SY5Y cell line.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00225C, Minireview
Iron and oxygen metabolism are intimately linked with one another.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00230J, Minireview
Chelation-induced fluorescence changes in low molecular weight molecules (probes) and genetically encoded proteins (sensors) allow for measuring fluctuations of cellular zinc(II) ion concentrations.
 
M. J. Ceko, K. Hummitzsch, N. Hatzirodos, W. M. Bonner, J. B. Aitken, D. L. Russell, M. Lane, R. J. Rodgers and H. H. Harris
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00228H, Paper
Using XRF imaging as a path-finding experiment, we mapped the distribution of trace elements in sections of bovine ovaries; the first study of its kind in mammalian ovaries.
 

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