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Journal cover: Metallomics


Global approaches to metals in the biosciences
Impact Factor 3.585 12 Issues per Year Indexed in Medline
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Elena V. Polishchuk and Roman S. Polishchuk
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00058D, Minireview
The lysosomal system operates as a focal point where a number of important physiological processes such as endocytosis, autophagy and nutrient sensing converge.
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00093B, Paper
The ATP7A protein is a ubiquitous copper-transporting P-type ATPase that is mutated in the lethal pediatric disorder of copper metabolism, Menkes disease.
Kyung Chan Park, Leyla Fouani, Patric J. Jansson, Danson Wooi, Sumit Sahni, Darius J. R. Lane, Duraippandi Palanimuthu, Hiu Chuen Lok, Zaklina Kovačević, Michael L. H. Huang, Danuta S. Kalinowski and Des R. Richardson
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00105J, Critical Review
Copper is an essential trace metal required by organisms to perform a number of important biological processes.
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C6MT00099A, Paper
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease, a fatal degenerative disorder in which motor neurons in the central nervous system (CNS) progressively deteriorate. Most...
Niraj S. Ghatpande, Priti P. Apte, Sadanand S. Naik, Bimba N. Joshi, Medha K. Gokhale and Prasad Padmakar Kulkarni
Metallomics, 2016, Accepted Manuscript
DOI: 10.1039/C6MT00129G, Communication
We investigated the association between iron status, B12, and inflammatory markers among 101 adolescent girls. We found that B12 showed significant negative association with tumor necrosis factor-alpha (TNF-α) (rs=-0.232, P=0.020)...
Irina Naletova, Vincenzo G. Nicoletti, Danilo Milardi, Adriana Pietropaolo and Giuseppe Grasso
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00067C, Paper
The conformation and oligomerization state of BK are strongly affected by copper but not zinc and this in turn affects the activity of BK in cells.
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00021E, Paper
Copper containing fungicides are used to protect vineyards from fungal infections.
Gonzalo Perez-Siles, Adrienne Grant, Melina Ellis, Carolyn Ly, Aditi Kidambi, Mamdouh Khalil, Roxana M. Llanos, Sharon La Fontaine, Alleene V. Strickland, Stephan Züchner, Sandra Bermeo, Elysia Neist, Tara C. Brennan-Speranza, Reinaldo I. Takata, Carlos E. Speck-Martins, Julian F. B. Mercer, Garth A. Nicholson and Marina L. Kennerson
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00082G, Paper
We have generated an Atp7a conditional knock in mouse model of dHMNX expressing Atp7aT985I, the orthologue of the human ATP7AT994I identified in dHMNX patients.
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00051G, Paper
A new selenium supplementation regimen was applied to probe the response of the urinary selenium species and improve the understanding of selenium metabolism.
Chelsey D. Kline, Benjamin F. Gambill, Mary Mayfield, Svetlana Lutsenko and Ninian J. Blackburn
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00062B, Communication
Cuproproteins such as PHM and DBM mature in late endosomal vesicles of the mammalian secretory pathway where changes in vesicle pH are employed for sorting and post-translational processing.
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00037A, Paper
In response to ischemic conditions, Cu redistribution takes place although Cu concentration was decreased, leading to depressed Cu-dependent CCO activity but increased Cu-dependent LOX activity in the ischemic myocardium along with enhanced collagen deposition.
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00036C, Paper
Mass spectrometry reveals a high resolution overview of species formed by CopZ and Cu(I), and the effects of the physiological low molecular weight thiol bacillithiol.
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00070C, Paper
Yeast cells accumulate large quantities of ferric ions in their cell walls as they become metabolically inactive. This Fe can be reduced and mobilized as cells become metabolically active.
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00045B, Paper
Vanadium complexes were studied during recent years and considered as a representative of a new class of non-platinum metal antitumor agents in combination with their low toxicity.
Crysten E. Blaby-Haas, Madeli Castruita, Sorel T. Fitz-Gibbon, Janette Kropat and Sabeeha S. Merchant
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00063K, Paper
From themed collection Nickel in biology
Combinatorial genome-wide analyses of transcriptome changes in response to genetic mutation and environmental perturbations give insight into a network of oxygen, copper and nickel signaling.
Kristin M. Bompiani, Cheng-Yu Tsai, Felix P. Achatz, Janika K. Liebig and Stephen B. Howell
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00076B, Paper
We used CRISPR-Cas9 technology to address whether copper transporters or chaperones CTR1, CTR2, ATOX1, and CCS mediate cisplatin sensitivity in human cells.
Qinqin Cheng, Hongdong Shi, Hongxia Wang, Jun Wang and Yangzhong Liu
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00066E, Paper
From themed collection Fifth International Symposium on Metallomics, Beijing, China
Asplatin, the conjugate of aspirin and cisplatin, promotes cell apoptosis by highly efficient activation of the BCL-2 associated mitochondrial pathway.
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00289C, Paper
Gene expression and bioinformatics studies provide new insight into copper homeostasis in the methanotroph Methylosinus trichosporium OB3b.
Oliver Hachmöller, Ana Guilherme Buzanich, Michaela Aichler, Martin Radtke, Dörthe Dietrich, Kristina Schwamborn, Lisa Lutz, Martin Werner, Michael Sperling, Axel Walch and Uwe Karst
Metallomics, 2016, Advance Article
DOI: 10.1039/C6MT00001K, Paper
From themed collection Fifth International Symposium on Metallomics, Beijing, China
A liver biopsy specimen of a Wilson's disease patient was analyzed by means of micro-X-ray fluorescence (μXRF) and X-ray absorption near edge structure spectroscopy (XANES).
Wenjing Zhang, Xinmei Zhao, Ying Xiao, Jianmin Chen, Pengfei Han, Jingyao Zhang, Haiying Fu and Y. James Kang
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00332F, Paper
From themed collection Hot articles in Metallomics 2016
Copper loss in ischemic myocardium makes a critical contribution to the suppression of HIF-1-regulated angiogenesis.
Yunyun Li, Jiating Zhao, Yu-Feng Li, Xiaohan Xu, Bowen Zhang, Yongjie Liu, Liwei Cui, Bai Li, Yuxi Gao and Zhifang Chai
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00264H, Paper
From themed collection Fifth International Symposium on Metallomics, Beijing, China
The toxicity mechanisms of rice roots under inorganic mercury (IHg) or methylmercury (MeHg) stress were investigated using metalloproteomic approaches.
Metallomics, 2016, Advance Article
DOI: 10.1039/C5MT00242G, Communication
From themed collection Fifth International Symposium on Metallomics, Beijing, China
The molecular mechanism of CeONPs in protecting against neuronal cytotoxicity from amyloid peptides and copper ions was investigated systematically by photoluminescence of [Ru(phen)2dppz]2+, morphology of TEM, mass spectroscopy, cell viability assay, ROS fluorescence assay, and EPR.

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