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Journal cover: Metallomics

Metallomics

Global approaches to metals in the biosciences
Impact Factor 3.978 12 Issues per Year Indexed in Medline
 
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Tracy MacDonald, Malgorzata Korbas, ashley k james, nicole j sylvain, Mark Hackett , Susan Nehzati, Patrick H Krone, Graham George and Ingrid Pickering
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00145E, Paper
The compounds of mercury can be more toxic than those of any other non-radioactive heavy element. Despite this, environmental mercury pollution and human exposure to mercury are widespread, and are...
 
Y.J. Kang, Rui Li, Katherine Bourcy, Tao Wang and Miao Sun
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00094G, Paper
Dietary copper supplementation reverses pressure overload-induced cardiac hypertrophy. Activation of vascular endothelial growth factor receptor-1 (VEGFR-1) and cyclic guanosine monophosphate (cGMP)-dependent protein kinase-1 (PKG-1) is required for the regression. The...
 
Elena Vigonsky, Inbar Fish, Nurit Livnat-Levanon, Elena Ovcharenko, Nir Ben-Tal and Oded Lewinson
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00100E, Paper
The Bacillus anthracis virulence determinant MntA is a high-affinity manganese system.
 
Francesco Musiani, Barbara Zambelli, Micaela Bazzani, Luca Mazzei and Stefano Ciurli
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00072F, Minireview
From themed collection Nickel in biology
The structural features, metal coordination modes and metal binding thermodynamics of known Ni(II)-dependent transcriptional regulators are highlighted and discussed.
 
Magdalena Matczuk, Karolina Anecka, Federica Scaletti, Luigi Messori, Bernhard K. Keppler, Andrei R. Timerbaev and Maciej Jarosz
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00109A, Paper
A high-resolution CE-ICP-MS method is presented for monitoring and comprehensive understanding of the protein-mediated transformations of gold nanoparticles in human serum.
 
Fátima Brandão, Tiziana Cappello, Joana Raimundo, Maria Ana Santos, Maria Maisano, Angela Mauceri, Mário Pacheco and Patrícia Pereira
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00090D, Paper
Mercury hepatotoxicity was investigated in wild fish (Liza aurata) through assessment of metabolomic shifts, antioxidant system and Hg bioaccumulation.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00116A, Paper
The close connection of the reduction rate of PtIV complexes and their biological activity was studied in ovarian carcinoma cell lines.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00097A, Paper
Under physiological condition, CTR1 predominantly transports copper across cell membrane; when extracellular copper concentrations increase, CTR1 decreases and DMT1 compensates for the loss of CTR1 to transport copper into HUVECs.
 
Iris Koch, Jing Zhang, Mark Button, Laura A. Gibson, Guilhem Caumette, Valerie S. Langlois, Kenneth J. Reimer and William R. Cullen
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00078E, Paper
Silurana tropicalis tadpoles and frogs exposed to arsenate exhibit changes in levels of methylating enzymes DNMT1 and AS3MT, and methylate arsenic to trimethylarsine oxide and tetramethylarsonium.
 
Mojca Mattiazzi Ušaj, Metod Prelec, Mojca Brložnik, Cecilia Primo, Tomaž Curk, Janez Ščančar, Lynne Yenush and Uroš Petrovič
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00095E, Paper
Izh2 acts as an integrator of intra- and extracellular signals. It dispatches a single input signal – a change in extracellular Zn concentration – into regulatory networks of several cellular processes, whereby it acts as the second line of cellular adaptation to perturbations to zinc homeostasis.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00070J, Paper
QM/MM calculations on thiolate disulfide exchange reveal that a polar, 4-centered, cyclic transition state is formed when Zn(II) is present, helping to explain faster exchange rates in higher dielectric solvents for metal-assisted exchange.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00054H, Paper
Quantitative analysis of metal selectivity of overexpressed metalloproteins in cells by GE-ICP-MS.
 
Barbara Crone, Michael Aschner, Tanja Schwerdtle, Uwe Karst and Julia Bornhorst
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00096C, Paper
Laser ablation-inductively coupled plasma mass spectrometry imaging reveals the Cisplatin distribution in C. elegans.
 
Bárbara Rita Cardoso, Blaine R. Roberts, Ashley I. Bush and Dominic J. Hare
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00075K, Critical Review
A review of selenium's essential role in normal brain function and its potential involvement in neurodegenerative diseases.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00086F, Paper
Organotins, such as tributyltin (TBT) and triphenyltin (TPT), may disrupt endocrine activity in mammals arising from their ability to act as ligands for the retinoid X receptor (RXR) and the peroxisome proliferator-activated receptor γ (PPARγ).
 
Edgar Augusto Ortiz-Benitez, Mariana Carrillo-Morales, Norma Velázquez-Guadarrama, Jesús Fandiño-Armas and José de Jesús Olivares-Trejo
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00044K, Paper
In this work, we study the antibacterial effect of AuNPs in S. pneumoniae.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00076A, Minireview
Metal ions, i.e., Zn2+ and Cu2+, are released from neuron terminals in the hippocampus, which plays important roles in spatial and declarative memory, and may serve as a signal factor. Aβ is bound to Zn2+ and Cu2+ in the extracellular compartment and forms oligomers, potentially followed by transiently cognitive decline.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00053J, Paper
Methionine and lysine residues are important for preserving the structure of the CusB N-terminal domain and for the interaction with CusF.
 
Łukasz Szyrwiel, Mari Shimura, Junko Shirataki, Satoshi Matsuyama, Akihiro Matsunaga, Bartosz Setner, Łukasz Szczukowski, Zbigniew Szewczuk, Kazuto Yamauchi, Wiesław Malinka, Laurent Chavatte and Ryszard Łobinski
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00021A, Paper
A novel branched TAT47–57 peptide transported Ni2+ into the human cell nucleus efficiently.
 
E. Atrián-Blasco, E. Cerrada, A. Conte-Daban, D. Testemale, P. Faller, M. Laguna and C. Hureau
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00077G, Communication
The use of a Cu(I) stabilizing ligand to target copper ions is a very promising approach against Alzheimer's disease.
 
Shohei Segawa, Nao Tatsumi, Akihiro Ohishi, Kentaro Nishida and Kazuki Nagasawa
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00085H, Paper
Astrocytes uptake zinc as a clearance system to maintain the extracellular zinc level, while microglia take it up as a signal transmitter.
 
Marco Roverso, Chiara Berté, Valerio Di Marco, Annunziata Lapolla, Denis Badocco, Paolo Pastore, Silvia Visentin and Erich Cosmi
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00050E, Paper
The metallome of gestational diabetes mellitus (GDM) was reviewed, and a metallomics study was performed in human placenta. GDM placentas contain less cadmium and more selenium than healthy placentas.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00033E, Paper
Organotin compounds, such as tributyltin (TBT), are well-known endocrine disruptors.
 
Qi-Pin Qin, Yan-Cheng Liu, Hai-Lu Wang, Jiao-Lan Qin, Feng-Jie Cheng, Shang-Feng Tang and Hong Liang
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00027K, Paper
A copper(II) complex of anthracene-9-imidazoline hydrazone induced cell apoptosis by suppressing mutant p53 expression and activating caspase cascade pathway.
 
Mauricio Latorre, Marcela Low, Esteban Gárate, Angélica Reyes-Jara, Barbara E. Murray, Verónica Cambiazo and Mauricio González
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00043B, Paper
By integrating the microarray expression data and a global E. faecalis transcriptional network we identified a sub-network activated by zinc and copper.
 

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