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Metallomics

Global approaches to metals in the biosciences
Impact Factor 3.978 12 Issues per Year Indexed in MEDLINE
 
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Martin Herzberg, Marcel Schüttau, Matthias Reimers, Cornelia Große, Hans-Günther-Schlegel and Dietrich H. Nies
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00297K, Paper
From themed collection Nickel in biology
In Cupriavidus metallidurans disturbed metal homeostasis silences catabolic metabolic genomic islands (CMGIs) containing genes for nickel-dependent hydrogenases. This situation is reverted in a ΔzupT mutant.
 
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00012B, Minireview
Abstract Iron-sulfur clusters act as important cofactors for a number of transcriptional regulators in bacteria, including many mammalian pathogens. The sensitivity of iron-sulfur clusters to iron availability, oxygen tension, and...
 
Fatai Adigun Aborode, Andrea Raab, Simon Foster, Enzo Lombi, William Maher, Eva Krupp and Jorg Feldmann
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00025D, Paper
Three months old Thunbergia alata were exposed for 13 days to 10 μM selenite to determine the biotransformation of selenite in their roots. Selenium in formic acid extracts (80 ±...
 
Melania D'Orazio, Maria Chiara Mastropasqua, Mauro Cerasi, Francesca Pacello, Ada Consalvo, Barbara Chirullo, Brittany L. Mortensen, Eric Skaar, Domenico Ciavardelli, Paolo Pasquali and Andrea Battistoni
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00017C, Paper
The ability of a large number of bacterial pathogens to multiply in the infected host and cause disease is dependent on their ability to express high affinity zinc importers. In...
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00037H, Paper
The studied Ru polypyridyl complexes are ca. ten times more cytotoxic against breast cancer (4T1) and human lung adenocarcinoma epithelial cells (A549) than cisplatin and have a distinct impact on cell adhesion, migration and endothelial cell vasculature.
 
Tessa R. Young, Chathuri J. K. Wijekoon, Benjamin Spyrou, Paul S. Donnelly, Anthony G. Wedd and Zhiguang Xiao
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00301B, Paper
A set of four fluorescent probes were developed and demonstrated to be capable of quantifying Cu(II) binding affinities in the micromolar to femtomolar range and exploring Cu(II) binding ligands in peptides and proteins.
 
S. A. Kozin, A. A. Kulikova, A. N. Istrate, P. O. Tsvetkov, S. S. Zhokhov, Y. V. Mezentsev, O. I. Kechko, A. S. Ivanov, V. I. Polshakov and A. A. Makarov
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00259H, Communication
The English familial mutation causes the exclusion of His6 from the zinc chelation pattern and triggers the assembly of Aβ1–16 dimers.
 
Xiaoxue Wang, Xiaoli Mu, Jie Zhang, Qingyu Huang, Ambreen Alamdar, Meiping Tian, Liangpo Liu and Heqing Shen
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00002E, Paper
Chronic arsenic exposure induces metabolome disruption in rat.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00318G, Paper
From themed collection Nickel in biology
In nickel-tolerant Streptomyces coelicolor, a highly nickel-sensitive regulator (Nur) for nickel uptake systems and an extremely insensitive regulator (NmtR) for a nickel efflux pump constitute the nickel homeostasis system.
 
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00011D, Paper
Copper is universally toxic in excess, a feature exploited by the human immune system to facilitate bacterial clearance. The mechanism of copper intoxication remains unknown for many bacterial species. Here,...
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00023H, Paper
A combined approach of FluoroGold™ retrograde tracer injection and XRF imaging to perform in situ measurement of manganese content and distribution in dopaminergic cells of the rodent substantia nigra compacta.
 
Timothy M. Ryan, Nigel Kirby, Haydyn D. T. Mertens, Blaine Roberts, Kevin J. Barnham, Roberto Cappai, Chi Le Lan Pham, Colin L. Masters and Cyril C. Curtain
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00323C, Paper
Research into causes of Alzheimer's disease and its treatment has produced a tantalising array of hypotheses about the role of transition metal dyshomeostasis, many of them on the interaction of these metals with the neurotoxic amyloid-β peptide (Aβ).
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00329B, Minireview
Uropathogenic Escherichia coli (UPEC) may produce upto four siderophores during urinary tract infection (UTI). Host cells produce lipocalin, calprotectin and ceruloplasmin during UTI. Arrows indicate the direction of metal transport in UPEC during UTI.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00001G, Paper
The methionine-rich insert in the multicopper oxidase CueO from E. coli accommodates three copper sites that play distinct but related roles in Cu(I) extraction and oxidation and that induce robust cuprous oxidase activity under physiologically relevant conditions.
 
Patrícia Pereira, Joana Raimundo, Marisa Barata, Olinda Araújo, Pedro Pousão-Ferreira, João Canário, Armando Almeida and Mário Pacheco
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00291A, Paper
Time-related accumulation/distribution of inorganic Hg upon exposure and post-exposure periods. Body compartments selected: gills, eye wall, lens, blood, liver, brain and bile.
 
Melanie J. Ceko, Katja Hummitzsch, Nicholas Hatzirodos, Wendy Bonner, Simon A. James, Jason K. Kirby, Raymond J. Rodgers and Hugh H. Harris
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00338A, Paper
The first study of bromine speciation and distribution in mammalian tissues using X-rays shows bromine present predominantly as bromide.
 
Jing Wang, Ru Bai, Ru Yang, Jing Liu, Jinglong Tang, Ying Liu, Jiayang Li, Zhifang Chai and Chunying Chen
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00340C, Paper
It is important and essential to study the pharmacokinetics and biodistribution of gold nanoparticles for safer and more efficient therapeutic purposes.
 
Eszter Emri, Edit Miko, Péter Bai, Gábor Boros, Georgina Nagy, Dávid Rózsa, Tamás Juhász, Csaba Hegedűs, Irén Horkay, Éva Remenyik and Gabriella Emri
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00287C, Paper
The exposure of human keratinocytes to non-toxic concentrations of ZnCl2 impacts gene expression, cell proliferation and the response to UVB.
 
Alexander E. Egger, Christoph Kornauth, Werner Haslik, Stephan Hann, Sarah Theiner, Günther Bayer, Christian G. Hartinger, Bernhard K. Keppler, Ursula Pluschnig and Robert M. Mader
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00308J, Paper
Spatially resolved quantification of platinum distribution in patients that exhibited extravasation was feasible up to 4 weeks upon drug application.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00315B, Paper
Iron decreases IRP-1 protein levels in renal cells in a ROS-independent manner, while increasing both aconitase activity and glutamate levels.
 
Marta Albareda, Agnès Rodrigue, Belén Brito, Tomás Ruiz-Argüeso, Juan Imperial, Marie-Andrée Mandrand-Berthelot and Jose Palacios
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00298A, Paper
From themed collection Nickel in biology
Functional and topological analysis of Rhizobium leguminosarum HupE, the founding member of the HupE/UreJ family of nickel permeases, provides new hints on how bacteria manage nickel provision for metalloenzyme synthesis.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00331D, Perspective
A link between environmental pH and fungal zinc uptake strategies? Soil acidity and endemic mycoses in the USA.
 
Erik Ladomersky and Michael J. Petris
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00327F, Minireview
Copper (Cu) is an essential trace element for all aerobic organisms.
 
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00339J, Minireview
The interaction of different metals with the Parkinson's disease-associated protein alpha-synuclein results in oxidative stress, protein aggregation and pathology progression.
 
Marta Costas-Rodríguez, Yulia Anoshkina, Sara Lauwens, Hans Van Vlierberghe, Joris Delanghe and Frank Vanhaecke
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00319E, Paper
The isotopic composition of blood serum Cu has been investigated as a potential parameter for the diagnosis and prognosis of liver cirrhosis.
 

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