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Journal cover: Metallomics


Global approaches to metals in the biosciences
Impact Factor 3.978 12 Issues per Year Indexed in MEDLINE
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D. B. Zamble
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT90013A, Editorial
From themed collection Nickel in biology
This editorial introduces the Nickel in Biology themed issue for Metallomics, guest edited by Deborah Zamble.
Eun-Ik Koh, Chia S. Hung, Kaveri S. Parker, Jan R. Crowley, Daryl E. Giblin and Jeffrey P. Henderson
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00341A, Paper
Metal–yersiniabactin complexes are transported intact through the outer membrane receptor, FyuA, in a TonB-dependent manner in uropathogenic Escherichia coli.
Sarah Theiner, Christoph Kornauth, Hristo Plamenov Varbanov, Markus Galanski, Sushilla van Schoonhoven, Petra Heffeter, Walter Berger, Alexander E Egger and Bernhard K Keppler
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00028A, Paper
The selection of drug candidates for entering clinical development relies on in vivo testing in (solid) tumor animal models. However, the heterogeneity of tumor tissue (e.g. in terms of drug...
M. J. Ceko, K. Hummitzsch, N. Hatzirodos, R. J. Rodgers and H. H. Harris
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00035A, Paper
Highlights how quantitative XRF can differentiate between biological structures in bovine ovaries on the basis of trace element distribution alone.
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00010F, Paper
To evaluate the anticancer mechanism of the new ruthenium complex-Λ-WH0402 at the cellular level, the in vitro cytotoxicity of Λ-WH0402 was investigated on 10 human tumor cell lines.
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00009B, Paper
The intracellular concentration of Mn-phosphates does not correlate with radioresistance.
David Haschka, Manfred Nairz, Egon Demetz, Sebastian Wienerroither, Thomas Decker and Günter Weiss
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00328D, Paper
Due to its multiple roles for the proliferation and pathogenicity of many microbes on the one hand and via modulation of immune effector functions on the other hand the control...
Celina Støving Dam, Sergio Alejo Perez Henarejos, Theodosia Tsolakou, Christian Alexander Segato, Bente Gammelgaard, Gorakh S. Yellol, José Ruiz, Ian Henry Lambert and Stefan Stürup
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00056D, Paper
Applying a novel protocol for the characterization of metal-based drugs reveals the potential of a new Ru-based compound in overcoming Cisplatin resistance.
Dai Mizuno, Keiko Konoha–Mizuno, Miwako Mori, Yutaka Sadakane, Hironari KOYAMA, Susumu Ohkawara and Masahiro Kawahara
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00049A, Paper
Carnosine (β–alanyl–L–histidine) is a small dipeptide with numerous beneficial effects, including the maintenance of the acid–base balance, antioxidant properties, chelating agent, anti–crosslinking, and anti–glycation activities. High levels of carnosine and...
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C5MT00055F, Paper
The current study aimed to explore how gadolinium (Gd)-based contrast agent (GBCA) Omniscan® enhanced cell viability of murine fibroblasts. The results showed that Omniscan® can precipitate in cell culture media...
Maria Joanna Niemiec, Björn De Samber, Jan Garrevoet, Eva Vergucht, Bart Vekemans, Riet De Rycke, Erik Björn, Linda Sandblad, Gerd Wellenreuther, Gerald Falkenberg, Peter Cloetens, Laszlo Vincze and Constantin Felix Urban
Metallomics, 2015, Accepted Manuscript
DOI: 10.1039/C4MT00346B, Paper
Every infection is a battle for trace elements. Neutrophils migrate first to the infection site and accumulate quickly to high numbers. They fight pathogens by phagocytosis and intracellular toxication. Additionally,...
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00005J, Paper
New members of the synechobactin siderophore suite with variable hydroxamate chain length were discovered using an LCMS based pipeline for the sensitive characterization of iron complexes.
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00309H, Paper
From themed collection Nickel in biology
Novel Ni-coordination in a [NiFe]-hydrogenase mutant and possible coexistence of hydride and sulfenic acid in the WT Ni-SIb state.
David G. Workman, Andrew Tsatsanis, Frank W. Lewis, John P. Boyle, Maryam Mousadoust, Nishani T. Hettiarachchi, Michael Hunter, Chris S. Peers, David Tétard and James A. Duce
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00326H, Paper
We report that novel 1-hydroxypyridin-2-ones show comparable neuroprotective results to deferiprone in a cell culture model of Parkinson's disease.
Yosuke Tabei, Akinari Sonoda, Yoshihiro Nakajima, Vasudevanpillai Biju, Yoji Makita, Yasukazu Yoshida and Masanori Horie
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00031A, Paper
Indium tin oxide (ITO) nanoparticles are taken up by human lung adenocarcinoma cells and the nanoparticles induce oxidative stress and DNA damage.
Chandana Pandey, Badmi Raghuram, Alok Krishna Sinha and Meetu Gupta
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00013K, Paper
We report that miRNA plays an important role in the selenium mediated antagonistic effect on arsenic stress in rice seedlings.
Sudipta Chakraborty, Pan Chen, Julia Bornhorst, Tanja Schwerdtle, Fabian Schumacher, Burkhard Kleuser, Aaron B. Bowman and Michael Aschner
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00052A, Paper
This study provides further support that altered metal homeostasis is a critical component of PD pathophysiology.
Rebekka Hueting, Veerle Kersemans, Matthew Tredwell, Bart Cornelissen, Martin Christlieb, Antony D. Gee, Jan Passchier, Sean C. Smart, Véronique Gouverneur, Ruth J. Muschel and Jonathan R. Dilworth
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00330F, Paper
A pair of [123I]/[64Cu]-copper bis(thiosemicarbazonates), radiolabelled at either the metal or at the ligand, was used to examine the roles of the copper metal and the ligand in the in vitro and in vivo behaviour of this class of hypoxia PET imaging agent.
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00024F, Paper
Proteomic responses to zinc and cadmium in O. maius suggest an increase in polyamine biosynthesis through a novel pathway in fungi.
Victoria I. Holden and Michael A. Bachman
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00333K, Critical Review
Specialization of siderophore function during infection: Salmochelin (Sal) evades Lipocalin 2 (Lcn2) to scavenge iron, Enterobactin (Ent) promotes lung invasion, and Yersiniabactin (Ybt) binds copper for detoxification and zinc for nutrition.
Fatai Adigun Aborode, Andrea Raab, Simon Foster, Enzo Lombi, William Maher, Eva M. Krupp and Joerg Feldmann
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00025D, Paper
T. alata plants were exposed to 10 μM selenite to determine biotransformation of selenium in their roots using HPLC-ICPMS/ESIMS and EXAFS.
Melania D'Orazio, Maria Chiara Mastropasqua, Mauro Cerasi, Francesca Pacello, Ada Consalvo, Barbara Chirullo, Brittany Mortensen, Eric P. Skaar, Domenico Ciavardelli, Paolo Pasquali and Andrea Battistoni
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00017C, Paper
Zn acquisition in Pseudomonas aeruginosa.
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00012B, Minireview
We review how iron–sulfur cluster-containing regulators contribute to bacterial pathogenesis through control of gene expression in response to environmental cues.
Michael D. L. Johnson, Thomas E. Kehl-Fie and Jason W. Rosch
Metallomics, 2015, Advance Article
DOI: 10.1039/C5MT00011D, Paper
Graphical model of copper export and toxicity in S. pneumoniae.
Martin Herzberg, Marcel Schüttau, Matthias Reimers, Cornelia Große, Hans-Günther-Schlegel and Dietrich H. Nies
Metallomics, 2015, Advance Article
DOI: 10.1039/C4MT00297K, Paper
From themed collection Nickel in biology
In Cupriavidus metallidurans disturbed metal homeostasis silences catabolic metabolic genomic islands (CMGIs) containing genes for nickel-dependent hydrogenases. This situation is reverted in a ΔzupT mutant.

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